Translation of Near-Infrared Fluorescence Imaging Technologies: Emerging Clinical Applications: Supplemental Video 2

A supplemental video from the 2012 review by E.M. Sevick-Muraca, "Translation of Near-Infrared Fluorescence Imaging Technologies: Emerging Clinical Applications," from the Annual Review of Medicine.

Stimulation of lymphatic propulsion in the foot and calf of a normal healthy volunteer before and during manual lymphatic drainage. The fluorescence from the indocyanine green (ICG) becomes scattered by tissues as the lymphatic vasculature drains into deeper vessels. The shadow on the ankle arises from black plastic that covers the injection site so that the ICCD (intensified charged coupled device) camera is not oversaturated. Reproduced with permission from Reference 25.