Translation of Near-Infrared Fluorescence Imaging Technologies: Emerging Clinical Applications: Supplemental Video 3

A supplemental video from the 2012 review by E.M. Sevick-Muraca, "Translation of Near-Infrared Fluorescence Imaging Technologies: Emerging Clinical Applications," from the Annual Review of Medicine. 

Investigational NIRF images of the lymphatics in the anteriolateral territory of the right upper arm and left hand in a 67-year-old male with grade I lymphedema presenting approximately six months after carpal tunnel syndrome surgery. Imaging was performed 11 months after onset of symptoms. Lymphatics are contrasted by IGC and show active lymphatic propulsion to the axilla. Analysis of the video demonstrates that the tortuous lymphatic vasculature drains from the edematous regions of the anterior upper arm into the medial lymph bundle. Because the lymphatics cannot be conventionally imaged with the temporal and spatial resolution shown herein, it is not known whether tortuous lymphatic vessels are the result or the cause of edema.