High-Speed AFM and Applications to Biomolecular Systems: Supplemental Video 3

A supplemental video from the 2013 review by Toshio Ando, Takayuki Uchihashi, and Noriyuki Kodera, "High-Speed AFM and Applications to Biomolecular Systems," from the Annual Review of Biophysics.

Hand-over-hand movement of myosin V (M5-HMM) including foot stomp of the leading head. The dynamic process in 1 µM ATP was captured at 7 fps. Scan range, 150 × 75 nm2 with 80 × 40 pixel. Five frames are selected and shown in Figure 4c. Foot stomp events occurred at the leading head are marked with light-blue triangles.