Spatiotemporal Basis of Innate and Adaptive Immunity in Secondary Lymphoid Tissue: Video 9
Abstract
A video from the 2014 review by Hai Qi, Wolfgang Kastenmüller, and Ronald N. Germain, "Spatiotemporal Basis of Innate and Adaptive Immunity in Secondary Lymphoid Tissue," from the Annual Review of Cell and Developmental Biology.
Shown: T cells exit HEVs in limited locations
A single z slice from an intravital 4D data set showing numerous T cells exiting HEV via lucent areas that appear to be gaps in the FRC sheath ("exit ramps").
Original publication: Bajenoff M, Egen JG, Koo LY, Laugier JP, Brau F, et al. 2006. Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. Immunity 25:989–1001
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