Single-Cell Studies of Phage λ: Hidden Treasures Under Occam's Rug: Video 2

A video from the 2016 review by Ido Golding, "Single-Cell Studies of Phage λ: Hidden Treasures Under Occam’s Rug," from the Annual Review of Virology.

Shown: Tracking the postinfection decision (see also Figure 2d ). Phage capsids were labeled using gpD-YFP. At t = 0, two cells are each infected by a single phage (green), and one cell is infected by three phages. The two cells infected by single phages go into the lytic pathway, as indicated by the intracellular production of new phage capsids (green). The cell infected by three phages goes into the lysogenic pathway, as indicated by the activity of a P_RE-mCherry reporter (red). Eventually, the lytic pathway results in cell lysis, whereas the lysogenic cell continues to grow and divide. Video reproduced from Zeng et al. 2010, Cell 141:682–91, with permission from Elsevier.