Single-Cell Studies of Phage λ: Hidden Treasures Under Occam's Rug: Video 8

A video from the 2016 review by Ido Golding, "Single-Cell Studies of Phage λ: Hidden Treasures Under Occam’s Rug," from the Annual Review of Virology.

Shown: Spatiotemporal dynamics of the phage genome inside the cell during the lytic pathway. At t = 0 min, the cell is infected by a gpD-YFP-labeled phage (green). At t = 5 min, a SeqA-ECFP focus corresponding to the injected phage DNA appears. Later, this focus is converted to two foci, corresponding to two hemimethylated phage DNAs. The cell eventually lyses (not shown). Video reproduced from Shao et al. 2015, Biophys. J. 108:2048–60, with permission from Elsevier.