1932

Abstract

Despite long-standing observations on diverse cytokinin actions, the discovery path to cytokinin signaling mechanisms was tortuous. Unyielding to conventional genetic screens, experimental innovations were paramount in unraveling the core cytokinin signaling circuitry, which employs a large repertoire of genes with overlapping and specific functions. The canonical two-component transcription circuitry involves His kinases that perceive cytokinin and initiate signaling, as well as His-to-Asp phosphorelay proteins that transfer phosphoryl groups to response regulators, transcriptional activators, or repressors. Recent advances have revealed the complex physiological functions of cytokinins, including interactions with auxin and other signal transduction pathways. This review begins by outlining the historical path to cytokinin discovery and then elucidates the diverse cytokinin functions and key signaling components. Highlights focus on the integration of cytokinin signaling components into regulatory networks in specific contexts, ranging from molecular, cellular, and developmental regulations in the embryo, root apical meristem, shoot apical meristem, stem and root vasculature, and nodule organogenesis to organismal responses underlying immunity, stress tolerance, and senescence.

Associated Article

There are media items related to this article:
A Lecture in Plant Biology: Cytokinin Signaling Networks
Loading

Article metrics loading...

/content/journals/10.1146/annurev-arplant-042811-105503
2012-06-02
2024-03-29
Loading full text...

Full text loading...

/content/journals/10.1146/annurev-arplant-042811-105503
Loading
/content/journals/10.1146/annurev-arplant-042811-105503
Loading

Data & Media loading...

Supplemental Material

Author Jen Sheen talks about cytokinin signaling networks in a related lecture.

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error