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Annual Review of Plant Biology

Volume 76, 2025

Autophagy in Plant Health and Disease

  • Angelina S. Gross1,2, Margot Raffeiner3, Yonglun Zeng4,5, Suayib Üstün3 and Yasin Dagdas1
  • 1Gregor Mendel Institute of Molecular Plant Biology, Vienna, Austria; email: [email protected] 2Current affiliation: Department of Applied Genetics and Cell Biology, Institute of Molecular Plant Biology, BOKU University of Natural Resources and Life Sciences, Vienna, Austria 3Faculty of Biology and Biotechnology, Ruhr University Bochum, Bochum, Germany 4State Key Laboratory of Plant Diversity and Specialty Crops and Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, China 5University of Chinese Academy of Sciences, Beijing, China
  • Vol. 76:197-227 (Volume publication date May 2025)
  • First published as a Review in Advance on January 22, 2025
  • Copyright © 2025 by the author(s).
    This work is licensed under a Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See credit lines of images or other third-party material in this article for license information.

Abstract

Autophagy has emerged as an essential quality control pathway in plants that selectively and rapidly removes damaged or unwanted cellular components to maintain cellular homeostasis. It can recycle a broad range of cargoes, including entire organelles, protein aggregates, and even invading microbes. It involves the de novo biogenesis of a new cellular compartment, making it intimately linked to endomembrane trafficking pathways. Autophagy is induced by a wide range of biotic and abiotic stress factors, and autophagy mutant plants are highly sensitive to stress, making it an attractive target for improving plant stress resilience. Here, we critically discuss recent discoveries related to plant autophagy and highlight open questions and future research areas.

Keyword(s): abiotic stress, biotic stress, cell biology, development, macroautophagy
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2025-05-20
2025-06-19
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Autophagy in Plant Health and Disease
Annual Review of Plant Biology 76, 197 (2025); https://doi.org/10.1146/annurev-arplant-060324-094912
/content/journals/10.1146/annurev-arplant-060324-094912
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