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Annual Review of Biomedical Data Science

Volume 5, 2022

Genome Privacy and Trust

Abstract

Genomics data are important for advancing biomedical research, improving clinical care, and informing other disciplines such as forensics and genealogy. However, privacy concerns arise when genomic data are shared. In particular, the identifying nature of genetic information, its direct relationship to health status, and the potential financial harm and stigmatization posed to individuals and their blood relatives call for a survey of the privacy issues related to sharing genetic and related data and potential solutions to overcome these issues. In this work, we provide an overview of the importance of genomic privacy, the information gleaned from genomics data, the sources of potential private information leakages in genomics, and ways to preserve privacy while utilizing the genetic information in research. We discuss the relationship between trust in the scientific community and protecting privacy, illuminating a future roadmap for data sharing and study participation.

Keyword(s): cryptography, data sharing, genome privacy, information leakage
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/content/journals/10.1146/annurev-biodatasci-122120-021311
2022-08-10
2025-04-28
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Genome Privacy and Trust
Annual Review of Biomedical Data Science 5, 163 (2022); https://doi.org/10.1146/annurev-biodatasci-122120-021311
/content/journals/10.1146/annurev-biodatasci-122120-021311
/content/journals/10.1146/annurev-biodatasci-122120-021311
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