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Annual Review of Microbiology

Volume 78, 2024

Unpacking Alternative Features of the Bacterial Chemotaxis System

Abstract

The bacterial chemotaxis system is one of the best-understood cellular pathways and serves as the model for signal transduction systems. Most chemotaxis research has been conducted with transmembrane chemotaxis systems from and has established paradigms of the system that were thought to be universal. However, emerging research has revealed that many bacteria possess alternative features of their chemotaxis system, demonstrating that these systems are likely more complex than previously assumed. Here, we compare the canonical chemotaxis system of with systems that diverge in supramolecular architecture, sensory mechanisms, and protein composition. The alternative features have likely evolved to accommodate chemical specificities of natural niches and cell morphologies. Collectively, these studies demonstrate that bacterial chemotaxis systems are a rapidly expanding field that offers many new opportunities to explore this exceedingly diverse system.

Keyword(s): chemoreceptor, chemotaxis, histidine kinase, signal transduction
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2024-11-20
2025-04-25
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/content/journals/10.1146/annurev-micro-032421-110850
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Unpacking Alternative Features of the Bacterial Chemotaxis System
Annual Review of Microbiology 78, 169 (2024); https://doi.org/10.1146/annurev-micro-032421-110850
/content/journals/10.1146/annurev-micro-032421-110850
/content/journals/10.1146/annurev-micro-032421-110850
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