Measuring the Functioning Human Brain

The emergence of functional magnetic resonance imaging (fMRI) marked a significant technological breakthrough in the real-time measurement of the functioning human brain in vivo. In part because of their 4D nature (three spatial dimensions and time), fMRI data have inspired a great deal of statistical development in the past couple of decades to address their unique spatiotemporal properties. This article provides an overview of the current landscape in functional brain measurement, with a particular focus on fMRI, highlighting key developments in the past decade. Furthermore, it looks ahead to the future, discussing unresolved research questions in the community and outlining potential research topics for the future.