1932

Abstract

▪ Abstract 

Microtubules are dynamic polymers required for many aspects of eukaryotic cell function. The interphase microtubule network is essential for intracellular transport, organization, and cell polarization, whereas the mitotic spindle is required for chromosome segregation and cell division. Studies in different areas such as cell migration, mitosis, and asymmetric cell division have shown that Ran, Rho, and heterotrimeric G proteins regulate many aspects of microtubule functions. This review surveys how G protein–signaling coordinates microtubule polymerization and organization with specific cellular activities.

Loading

Article metrics loading...

/content/journals/10.1146/annurev.cellbio.20.012103.094648
2005-02-10
2024-04-16
Loading full text...

Full text loading...

/content/journals/10.1146/annurev.cellbio.20.012103.094648
Loading
/content/journals/10.1146/annurev.cellbio.20.012103.094648
Loading

Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error