1932

Abstract

can change its mating type as often as every generation by a highly choreographed, site-specific recombination event that replaces one allele with different DNA sequences encoding the opposite allele. The study of this process has yielded important insights into the control of cell lineage, the silencing of gene expression, and the formation of heterochromatin, as well as the molecular events of double-strand break-induced recombination. In addition, switching provides a remarkable example of a small locus control region—the Recombination Enhancer—that controls recombination along an entire chromosome arm.

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/content/journals/10.1146/annurev.genet.32.1.561
1998-12-01
2024-06-23
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  • Article Type: Review Article
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