1932

Abstract

Insulin resistance is an important feature in the pathogenesis of noninsulin-dependent diabetes mellitus. Some rare patients have syndromes associated with a severe form of insulin resistance, usually involving acanthosis nigricans and, in premenopausal females, hyperandrogenism. This review discusses two of the causes of insulin resistance: mutations in the insulin receptor gene and autoantibodies directed against the insulin receptor.

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/content/journals/10.1146/annurev.me.42.020191.002105
1991-02-01
2024-04-15
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/content/journals/10.1146/annurev.me.42.020191.002105
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  • Article Type: Review Article
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