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Annual Review of Medicine

Volume 66, 2015

Treatment of Recurrent and Severe Infection

Abstract

infection (CDI) is a serious complication of hospitalization and antibiotic use with a high mortality and very high costs. Despite appropriate treatment, a subset of patients develop chronic recurrent CDI. Some other patients develop severe and life-threatening colitis. The risk factors, pathogenesis, and treatment of recurrent CDI and severe CDI are discussed in this review. In particular, fecal microbiota transplantation (FMT) as a treatment strategy is outlined and a treatment algorithm incorporating FMT is described.

Keyword(s): donor feces, fidaxomicin, microbiota, transplantation
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2015-01-14
2024-04-19
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Treatment of Recurrent and Severe Clostridium Difficile Infection
Annual Review of Medicine 66, 373 (2015); https://doi.org/10.1146/annurev-med-070813-114317
/content/journals/10.1146/annurev-med-070813-114317
/content/journals/10.1146/annurev-med-070813-114317
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