Introduction to the Theme “Ion Channels and Neuropharmacology: From the Past to the Future”

Literature Cited

1. 1. 

   Brown DA. 2020. Neurons, receptors, and channels. Annu. Rev. Pharmacol. Toxicol. 60:9–30
   [Google Scholar]
2. 2. 

   Brown DA, Adams PR. 1980. Muscarinic suppression of a novel voltage-sensitive K⁺ current in a vertebrate neurone. Nature 283:673–76
   [Google Scholar]
3. 3. 

   Duncan AL, Song W, Sansom MSP 2020. Lipid-dependent regulation of ion channels and G protein–coupled receptors: insights from structures and simulations. Annu. Rev. Pharmacol. Toxicol. 60:31–50
   [Google Scholar]
4. 4. 

   Miyazawa A, Fujiyoshi Y, Unwin N 2003. Structure and gating mechanism of the acetylcholine receptor pore. Nature 423:949–55
   [Google Scholar]
5. 5. 

   García-Nafría J, Tate CG. 2020. Cryo-electron microscopy: moving beyond X-ray crystal structures for drug receptors and drug development. Annu. Rev. Pharmacol. Toxicol. 60:51–71
   [Google Scholar]
6. 6. 

   Masiulis S, Desai R, Uchanski T, Serna Martin I, Laverty D et al. 2019. GABA_A receptor signalling mechanisms revealed by structural pharmacology. Nature 565:454–59
   [Google Scholar]
7. 7. 

   Rasmussen SGF, Choi H-J, Rosenbaum DM, Kobilka TS, Thian FS et al. 2007. Crystal structure of the human β₂ adrenergic G-protein-coupled receptor. Nature 450:383–87
   [Google Scholar]
8. 8. 

   Shaik MM, Peng H, Lu J, Rits-Volloch S, Xu C et al. 2019. Structural basis of coreceptor recognition by HIV-1 envelope spike. Nature 565:318–23
   [Google Scholar]
9. 9. 

   Calebiro D, Grimes J. 2020. G protein–coupled receptor pharmacology at the single-molecule level. Annu. Rev. Pharmacol. Toxicol. 60:73–87
   [Google Scholar]
10. 10. 

    Wootten D, Miller LJ. 2020. Structural basis for allosteric modulation of class B G protein–coupled receptors. Annu. Rev. Pharmacol. Toxicol. 60:89–107
    [Google Scholar]
11. 11. 

    Santoro B, Shah MM. 2020. Hyperpolarization-activated cyclic nucleotide-gated channels as drug targets for neurological disorders. Annu. Rev. Pharmacol. Toxicol. 60:109–31
    [Google Scholar]
12. 12. 

    Catterall WA, Lenaeus MJ, Gamal El-Din TM 2020. Structure and pharmacology of voltage-gated sodium and calcium channels. Annu. Rev. Pharmacol. Toxicol. 60:133–54
    [Google Scholar]
13. 13. 

    Payandeh J, Scheuer T, Zheng N, Catterall WA 2011. The crystal structure of a voltage-gated sodium channel. Nature 475:353–58
    [Google Scholar]
14. 14. 

    Tang L, Gamal El-Din TM, Swanson TM, Pryde DC, Scheuer T et al. 2016. Structural basis for inhibition of a voltage-gated Ca²⁺ channel by Ca²⁺ antagonist drugs. Nature 537:117–21
    [Google Scholar]
15. 15. 

    Zhao Y, Huang G, Wu J, Wu Q, Gao S et al. 2019. Molecular basis for ligand modulation of a mammalian voltage-gated Ca²⁺ channel. Cell 177:1495–506.e12
    [Google Scholar]
16. 16. 

    Shen H, Liu D, Wu K, Lei J, Yan N 2019. Structures of human Na_v1.7 channel in complex with auxiliary subunits and animal toxins. Science 363:1303–8
    [Google Scholar]
17. 17. 

    Clairfeuille T, Cloake A, Infield DT, Llongueras JP, Arthur CP et al. 2019. Structural basis of α-scorpion toxin action on Na_v channels. Science 363:6433eaav8573
    [Google Scholar]
18. 18. 

    Wisedchaisri G, Tonggu L, McCord E, Gamal El-Din TM, Wang L et al. 2019. Resting-state structure and gating mechanism of a voltage-gated sodium channel. Cell 178:993–1003.e12
    [Google Scholar]
19. 19. 

    Man KNM, Navedo MF, Horne MC, Hell JW 2020. β₂ adrenergic receptor complexes with the L-type Ca²⁺ channel Ca_V1.2 and AMPA-type glutamate receptors: paradigms for pharmacological targeting of protein interactions. Annu. Rev. Pharmacol. Toxicol. 60:155–74
    [Google Scholar]
20. 20. 

    Cheung PW, Bouley R, Brown D 2020. Targeting the trafficking of kidney water channels for therapeutic benefit. Annu. Rev. Pharmacol. Toxicol. 60:175–94
    [Google Scholar]
21. 21. 

    Ge J, Li W, Zhao Q, Li N, Chen M et al. 2015. Architecture of the mammalian mechanosensitive Piezo1 channel. Nature 527:64–9
    [Google Scholar]
22. 22. 

    Xiao B. 2020. Levering mechanically activated Piezo channels for potential pharmacological intervention. Annu. Rev. Pharmacol. Toxicol. 60:195–218
    [Google Scholar]
23. 23. 

    Brown BM, Shim H, Christophersen P, Wulff H 2020. Pharmacology of small- and intermediate-conductance calcium-activated potassium channels. Annu. Rev. Pharmacol. Toxicol. 60:219–40
    [Google Scholar]
24. 24. 

    Lee CH, MacKinnon R. 2018. Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures. Science 360:508–13
    [Google Scholar]
25. 25. 

    Matsuda K, Ihara M, Sattelle DB 2020. Neonicotinoid insecticides: molecular targets, resistance, and toxicity. Annu. Rev. Pharmacol. Toxicol. 60:241–55
    [Google Scholar]
26. 26. 

    Bannister K, Sachau J, Baron R, Dickenson AH 2020. Neuropathic pain: mechanism-based therapeutics. Annu. Rev. Pharmacol. Toxicol. 60:257–74
    [Google Scholar]