Tuberculosis (TB) remains one of the top 10 causes of death worldwide. TB is a preventable and curable disease, yet 10.4 million contracted TB and 1.7 million died in 2016 according to the World Health Organization. Multi-drug resistant TB has infected 490,000. The UN challenges researchers, public health practitioners, and medical professionals to end the epidemic by 2030.
Our experts review the research that is making a positive impact in the fight against TB. 53 million lives were saved between 2000 and 2016 with diagnosis and treatment. Can we #EndTB in the next 12 years?
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Last updated 06/2021
Genetic Diversity in Mycobacterium tuberculosis Clinical Isolates and Resulting Outcomes of Tuberculosis Infection and Disease
Julian S. Peters, Nabila Ismail, Anzaan Dippenaar, Shuyi Ma, David R. Sherman, Robin M. Warren, and Bavesh D. Kana, Annual Review of Genetics
Development of New Tuberculosis Drugs: Translation to Regimen Composition for Drug-Sensitive and Multidrug-Resistant Tuberculosis
Jacqueline P. Ernest, Natasha Strydom, Qianwen Wang, Nan Zhang, Eric Nuermberger, Véronique Dartois, and Rada M. Savic, Annual Review of Pharmacology and Toxicology
The Global Landscape of Tuberculosis Therapeutics
Jeffrey A. Tornheim and Kelly E. Dooley, Annual Review of Medicine
The Innate Immune Response to Mycobacterium tuberculosis Infection
Mariëtta M. Ravesloot-Chávez, Erik Van Dis, and Sarah A. Stanley, Annual Review of Immunology
Perspectives and Advances in the Understanding of Tuberculosis
Rachel L. Kinsella, Dennis X. Zhu, Gregory A. Harrison, Anne E. Mayer Bridwell, Jerome Prusa, Sthefany M. Chavez, and Christina L. Stallings, Annual Review of Pathology: Mechanisms of Disease
Molecular Diagnostics for Mycobacterium tuberculosis Infection
Kristen V. Dicks and Jason E. Stout, Annual Review of Medicine
The Magic Bullets and Tuberculosis Drug Targets
Ying Zhang, Annual Review of Pharmacology and Toxicology
Aspects of Genetic Susceptibility to Human Infectious Diseases
Adrian V.S. Hill, Annual Review of Genetics
Host Genetics of Mycobacterial Diseases in Mice and Men: Forward Genetic Studies of BCG-osis and Tuberculosis
A. Fortin, J.L. Casanova, and P. Gros, Annual Review of Genomics and Human Genetics
Host-Pathogen Interactions in Emerging and Re-emerging Infectious Diseases: A Genomic Perspective of Tuberculosis, Malaria, Human Immunodeficiency Virus Infection, Hepatitis B, and Cholera
Janet M. McNicholl, Marie V. Downer, Venkatachalam Udhayakumar, Chester A. Alper, and David L. Swerdlow, Annual Review of Public Health
The Immune Response in Tuberculosis
Anne O'Garra, Paul S. Redford, Finlay W. McNab, Chloe I. Bloom, Robert J. Wilkinson, and Matthew P.R. Berry, Annual Review of Immunology
Tuberculosis Pathogenesis and Immunity
Jennifer A. Philips and Joel D. Ernst, Annual Review of Pathology: Mechanisms of Disease
Letting Sleeping dos Lie: Does Dormancy Play a Role in Tuberculosis?
Michael C. Chao and Eric J. Rubin, Annual Review of Microbiology
Mycobacterial Subversion of Chemotherapeutic Reagents and Host Defense Tactics: Challenges in Tuberculosis Drug Development
Liem Nguyen and Jean Pieters, Annual Review of Pharmacology and Toxicology
Extensively Drug-Resistant Tuberculosis: A New Face to an Old Pathogen
Sheela Shenoi and Gerald Friedland, Annual Review of Medicine
Prospects for Tuberculosis Elimination
Christopher Dye, Philippe Glaziou, Katherine Floyd, and Mario Raviglione, Annual Review of Public Health
Tuberculosis
Parvathi Tiruviluamala and Lee B. Reichman, Annual Review of Public Health
Bovine Tuberculosis in Cattle: Vaccines, DIVA Tests, and Host Biomarker Discovery
H. Martin Vordermeier, Gareth J. Jones, Bryce M. Buddle, R. Glyn Hewinson, and Bernardo Villarreal-Ramos, Annual Review of Animal Biosciences
Archaeological Evidence of Epidemics Can Inform Future Epidemics
Sharon N. DeWitte, Annual Review of Anthropology
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