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Abstract

Mindfulness meditation is increasingly incorporated into mental health interventions, and theoretical concepts associated with it have influenced basic research on psychopathology. Here, we review the current understanding of mindfulness meditation through the lens of clinical neuroscience, outlining the core capacities targeted by mindfulness meditation and mapping them onto cognitive and affective constructs of the Research Domain Criteria matrix proposed by the National Institute of Mental Health. We review efficacious applications of mindfulness meditation to specific domains of psychopathology including depression, anxiety, chronic pain, and substance abuse, as well as emerging efforts related to attention disorders, traumatic stress, dysregulated eating, and serious mental illness. Priorities for future research include pinpointing mechanisms, refining methodology, and improving implementation. Mindfulness meditation is a promising basis for interventions, with particular potential relevance to psychiatric comorbidity. The successes and challenges of mindfulness meditation research are instructive for broader interactions between contemplative traditions and clinical psychological science.

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2019-05-07
2024-06-22
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Literature Cited

  1. Alberts HJ, Thewissen R, Raes L 2012. Dealing with problematic eating behaviour: the effects of a mindfulness-based intervention on eating behaviour, food cravings, dichotomous thinking and body image concern. Appetite 58:3847–51
    [Google Scholar]
  2. Alsubaie M, Abbott R, Dunn B, Dickens C, Keil TF et al. 2017. Mechanisms of action in mindfulness-based cognitive therapy (MBCT) and mindfulness-based stress reduction (MBSR) in people with physical and/or psychological conditions: a systematic review. Clin. Psychol. Rev. 55:74–91Evaluates the evidence base for mechanisms of action in mindfulness meditation–based interventions using rigorous methodological criteria.
    [Google Scholar]
  3. Baer RA 2003. Mindfulness training as a clinical intervention: a conceptual and empirical review. Clin. Psychol. Sci. Pract. 10:2125–43
    [Google Scholar]
  4. Baer RA, Smith GT, Hopkins J, Krietemeyer J, Toney L 2006. Using self-report assessment methods to explore facets of mindfulness. Assessment 13:127–45
    [Google Scholar]
  5. Baldwin SA, Imel ZE 2013. Therapist effects: findings and methods. Bergin and Garfield's Handbook of Psychotherapy and Behavior Change MJ Lambert, AE Bergin 258–97 New York: Wiley
    [Google Scholar]
  6. Begley CG, Ellis LM 2012. Drug development: raise standards for preclinical cancer research. Nature 483:7391531–33
    [Google Scholar]
  7. Benish SG, Quintana S, Wampold BE 2011. Culturally adapted psychotherapy and the legitimacy of myth: a direct-comparison meta-analysis. J. Couns. Psychol. 58:3279–89
    [Google Scholar]
  8. Bernstein A, Hadash Y, Lichtash Y, Tanay G, Shepherd K, Fresco DM 2015. Decentering and related constructs: a critical review and metacognitive processes model. Perspect. Psychol. Sci. 10:5599–617
    [Google Scholar]
  9. Betancourt JR, Green AR, Carrillo JE, Ananeh-Firempong O 2003. Defining cultural competence: a practical framework for addressing racial/ethnic disparities in health and health care. Public Health Rep 118:4293–302
    [Google Scholar]
  10. Bowen S, Kurz AS 2012. Between-session practice and therapeutic alliance as predictors of mindfulness after mindfulness-based relapse prevention. J. Clin. Psychol. 68:3236–45
    [Google Scholar]
  11. Bowen S, Witkiewitz K, Clifasefi SL, Grow J, Chawla N et al. 2014. Relative efficacy of mindfulness-based relapse prevention, standard relapse prevention, and treatment as usual for substance use disorders: a randomized clinical trial. JAMA Psychiatry 71:5547–56
    [Google Scholar]
  12. Brewer JA, Elwafi HM, Davis JH 2013. Craving to quit: psychological models and neurobiological mechanisms of mindfulness training as treatment for addictions. Psychol. Addict. Behav. 27:2366–79
    [Google Scholar]
  13. Brewer JA, Garrison KA 2014. The posterior cingulate cortex as a plausible mechanistic target of meditation: findings from neuroimaging. Ann. N. Y. Acad. Sci. 1307:119–27
    [Google Scholar]
  14. Brewer JA, Worhunsky PD, Gray JR, Tang Y-Y, Weber J, Kober H 2011. Meditation experience is associated with differences in default mode network activity and connectivity. PNAS 108:5020254–59
    [Google Scholar]
  15. Brown KW, Ryan RM 2003. The benefits of being present: mindfulness and its role in psychological well-being. J. Personal. Soc. Psychol. 84:4822–48
    [Google Scholar]
  16. Bushnell MC, Čeko M, Low LA 2013. Cognitive and emotional control of pain and its disruption in chronic pain. Nat. Rev. Neurosci. 14:7502–11
    [Google Scholar]
  17. Cairncross M, Miller CJ 2016. The effectiveness of mindfulness-based therapies for ADHD: a meta-analytic review. J. Atten. Disord. https://doi.org/10.1177%2F1087054715625301
    [Crossref] [Google Scholar]
  18. Cavanagh K, Strauss C, Forder L, Jones F 2014. Can mindfulness and acceptance be learnt by self-help? A systematic review and meta-analysis of mindfulness and acceptance-based self-help interventions. Clin. Psychol. Rev. 34:2118–29
    [Google Scholar]
  19. Chadwick P, Strauss C, Jones A-M, Kingdon D, Ellett L et al. 2016. Group mindfulness-based intervention for distressing voices: a pragmatic randomised controlled trial. Schizophr. Res. 175:1168–73
    [Google Scholar]
  20. Chambers R, Gullone E, Allen NB 2009. Mindful emotion regulation: an integrative review. Clin. Psychol. Rev. 29:6560–72
    [Google Scholar]
  21. Chawla N, Collins S, Bowen S, Hsu S, Grow J et al. 2010. The Mindfulness-Based Relapse Prevention Adherence and Competence Scale: development, interrater reliability, and validity. Psychother. Res. 20:4388–97
    [Google Scholar]
  22. Cherkin DC, Anderson ML, Sherman KJ, Balderson BH, Cook AJ et al. 2017. Two-year follow-up of a randomized clinical trial of mindfulness-based stress reduction versus cognitive behavioral therapy or usual care for chronic low back pain. JAMA 317:6642–44
    [Google Scholar]
  23. Chiesa A, Calati R, Serretti A 2011. Does mindfulness training improve cognitive abilities? A systematic review of neuropsychological findings. Clin. Psychol. Rev. 31:3449–64
    [Google Scholar]
  24. Chu C-S, Stubbs B, Chen T-Y, Tang C-H, Li D-J et al. 2018. The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: a systematic review and meta-analysis. J. Affect. Disord. 225:2018234–45
    [Google Scholar]
  25. Coronado-Montoya S, Levis AW, Kwakkenbos L, Steele RJ, Turner EH, Thombs BD 2016. Reporting of positive results in randomized controlled trials of mindfulness-based mental health interventions. PLOS ONE 11:4e0153220
    [Google Scholar]
  26. Crane RS, Brewer J, Feldman C, Kabat-Zinn J, Santorelli S et al. 2017. What defines mindfulness-based programs? The warp and the weft. Psychol. Med. 47:6990–99Establishes concrete guidelines for consistency in the design and implementation of and training for MMBIs.
    [Google Scholar]
  27. Crane RS, Eames C, Kuyken W, Hastings RP, Williams JMG et al. 2013. Development and validation of the mindfulness-based interventions–Teaching Assessment Criteria (MBI:TAC). Assessment 20:6681–88
    [Google Scholar]
  28. Crane RS, Kuyken W 2013. The implementation of mindfulness-based cognitive therapy: learning from the UK health service experience. Mindfulness 4:3246–54
    [Google Scholar]
  29. Creswell JD 2017. Mindfulness interventions. Annu. Rev. Psychol. 68:491–516
    [Google Scholar]
  30. Creswell JD, Lindsay EK 2014. How does mindfulness training affect health? A mindfulness stress buffering account. Curr. Dir. Psychol. Sci. 23:6401–7
    [Google Scholar]
  31. Dahl CJ, Lutz A, Davidson RJ 2015. Reconstructing and deconstructing the self: cognitive mechanisms in meditation practice. Trends Cogn. Sci. 19:9515–23Surveys broader context of contemplative practice surrounding MM and relevance to cognitive psychology.
    [Google Scholar]
  32. Davidson RJ 2003. Alterations in brain and immune function produced by mindfulness meditation. Psychosom. Med. 65:4564–570
    [Google Scholar]
  33. Davidson RJ, Dahl CJ 2017. Outstanding challenges in scientific research on mindfulness and meditation. Perspect. Psychol. Sci. 13:162–65
    [Google Scholar]
  34. Davidson RJ, Kaszniak AW 2015. Conceptual and methodological issues in research on mindfulness and meditation. Am. Psychol. 70:7581–92In-depth discussion of theoretical challenges facing the field of MM research.
    [Google Scholar]
  35. Davidson RJ, McEwen BS 2012. Social influences on neuroplasticity: stress and interventions to promote well-being. Nat. Neurosci. 15:5689–95
    [Google Scholar]
  36. Davis JM, Manley AR, Goldberg SB, Smith SS, Jorenby DE 2014. Randomized trial comparing mindfulness training for smokers to a matched control. J. Subst. Abuse Treat. 47:3213–21
    [Google Scholar]
  37. DeCoster J, Sparks EA, Sparks JC, Sparks GG, Sparks CW 2015. Opportunistic biases: their origins, effects, and an integrated solution. Am. Psychol. 70:6499–514
    [Google Scholar]
  38. Dimidjian S, Arch JJ, Schneider RL, Desormeau P, Felder JN, Segal ZV 2016. Considering meta-analysis, meaning, and metaphor: a systematic review and critical examination of “third wave” cognitive and behavioral therapies. Behav. Ther. 47:6886–905
    [Google Scholar]
  39. Dimidjian S, Beck A, Felder JN, Boggs JM, Gallop R, Segal ZV 2014. Web-based mindfulness-based cognitive therapy for reducing residual depressive symptoms: an open trial and quasi-experimental comparison to propensity score matched controls. Behav. Res. Ther. 63:83–89
    [Google Scholar]
  40. Dimidjian S, Segal ZV 2015. Prospects for a clinical science of mindfulness-based intervention. Am. Psychol. 70:7593–620Outlines steps needed to fully establish MMBIs in mental health care, especially via implementation research.
    [Google Scholar]
  41. Dunne JD 2015. Buddhist styles of mindfulness: a heuristic approach. Handbook of Mindfulness and Self-Regulation BD Ostafin, MD Robinson, BP Meier 251–70 New York: Springer
    [Google Scholar]
  42. Farb NAS, Anderson AK, Segal ZV 2012. The mindful brain and emotion regulation in mood disorders. Can. J. Psychiatry 57:270–77
    [Google Scholar]
  43. Farb NAS, Daubenmier J, Price CJ, Gard T, Kerr C et al. 2015. Interoception, contemplative practice, and health. Front. Psychol. 6:763
    [Google Scholar]
  44. Farb NAS, Segal ZV, Mayberg H, Bean J, McKeon D et al. 2007. Attending to the present: mindfulness meditation reveals distinct neural modes of self-reference. Soc. Cogn. Affect. Neurosci. 2:4313–22
    [Google Scholar]
  45. Flückiger C, Del Re AC, Wampold BE, Horvath AO 2018. The alliance in adult psychotherapy: a meta-analytic synthesis. Psychotherapy 55:4316–40
    [Google Scholar]
  46. Fox KCR, Dixon ML, Nijeboer S, Girn M, Floman JL et al. 2016. Functional neuroanatomy of meditation: a review and meta-analysis of 78 functional neuroimaging investigations. Neurosci. Biobehav. Rev. 65:208–28
    [Google Scholar]
  47. Fox KCR, Nijeboer S, Dixon ML, Floman JL, Ellamil M et al. 2014. Is meditation associated with altered brain structure? A systematic review and meta-analysis of morphometric neuroimaging in meditation practitioners. Neurosci. Biobehav. Rev. 43:48–73
    [Google Scholar]
  48. Fuchs C, Lee JK, Roemer L, Orsillo SM 2013. Using mindfulness- and acceptance-based treatments with clients from nondominant cultural and/or marginalized backgrounds: clinical considerations, meta-analysis findings, and introduction to the special series. Cogn. Behav. Pract. 20:11–12
    [Google Scholar]
  49. Gallant SN 2016. Mindfulness meditation practice and executive functioning: breaking down the benefit. Conscious. Cogn. 40:116–30
    [Google Scholar]
  50. Garland EL, Froeliger B, Howard MO 2014a. Mindfulness training targets neurocognitive mechanisms of addiction at the attention-appraisal-emotion interface. Front. Psychiatry 4:173
    [Google Scholar]
  51. Garland EL, Froeliger B, Howard MO 2014b. Effects of mindfulness-oriented recovery enhancement on reward responsiveness and opioid cue-reactivity. Psychopharmacology 231:163229–38
    [Google Scholar]
  52. Garland EL, Gaylord SA, Fredrickson BL 2011. Positive reappraisal mediates the stress-reductive effects of mindfulness: an upward spiral process. Mindfulness 2:159–67
    [Google Scholar]
  53. Garland EL, Hanley AW, Baker AK, Howard MO 2017. Biobehavioral mechanisms of mindfulness as a treatment for chronic stress: an RDoC perspective. Chronic Stress 1:2470547017711912
    [Google Scholar]
  54. Garland EL, Howard MO 2018. Mindfulness-based treatment of addiction: current state of the field and envisioning the next wave of research. Addict. Sci. Clin. Pract. 13:14
    [Google Scholar]
  55. Garland EL, Thomas E, Howard MO 2014c. Mindfulness-oriented recovery enhancement ameliorates the impact of pain on self-reported psychological and physical function among opioid-using chronic pain patients. J. Pain Symptom Manag. 48:61091–99
    [Google Scholar]
  56. Gethin R 2015. Buddhist conceptualizations of mindfulness. Handbook of Mindfulness: Theory, Research, and Practice KW Brown, JD Creswell, RM Ryan 9–41 New York: Guilford Press
    [Google Scholar]
  57. Goldberg SB, Davis JM, Hoyt WT 2013. The role of therapeutic alliance in mindfulness interventions: therapeutic alliance in mindfulness training for smokers. J. Clin. Psychol. 69:9936–50
    [Google Scholar]
  58. Goldberg SB, Hoyt WT, Nissen-Lie HA, Nielsen SL, Wampold BE 2018a. Unpacking the therapist effect: impact of treatment length differs for high- and low-performing therapists. Psychother. Res. 28:4532–44
    [Google Scholar]
  59. Goldberg SB, Tucker RP, Greene PA, Davidson RJ, Kearney DJ, Simpson TL 2019. Mindfulness-based cognitive therapy for patients with current depression: a meta-analysis. Cogn.Behav.Ther In press.
    [Google Scholar]
  60. Goldberg SB, Tucker RP, Greene PA, Davidson RJ, Wampold BE et al. 2018b. Mindfulness-based interventions for psychiatric disorders: a systematic review and meta-analysis. Clin. Psychol. Rev. 59:52–60Quantifies effectiveness of mindfulness meditation–based interventions on disorder-specific symptoms across psychiatric conditions.
    [Google Scholar]
  61. Goldberg SB, Tucker RP, Greene PA, Simpson TL, Kearney DJ, Davidson RJ 2017. Is mindfulness research methodology improving over time? A systematic review. PLOS ONE 12:10e0187298
    [Google Scholar]
  62. Goldberg SB, Wielgosz J, Dahl C, Schuyler B, MacCoon DS et al. 2015. Does the Five Facet Mindfulness Questionnaire measure what we think it does? Construct validity evidence from an active controlled randomized clinical trial. Psychol. Assess. 28:81009–14
    [Google Scholar]
  63. Goldin PR, Morrison A, Jazaieri H, Brozovich F, Heimberg R, Gross JJ 2016. Group CBT versus MBSR for social anxiety disorder: a randomized controlled trial. J. Consult. Clin. Psychol. 84:5427–37
    [Google Scholar]
  64. Goldin P, Ziv M, Jazaieri H, Gross JJ 2012. Randomized controlled trial of mindfulness-based stress reduction versus aerobic exercise: effects on the self-referential brain network in social anxiety disorder. Front. Hum. Neurosci. 6:295
    [Google Scholar]
  65. Gotink RA, Meijboom R, Vernooij MW, Smits M, Hunink MGM 2016. 8-week mindfulness based stress reduction induces brain changes similar to traditional long-term meditation practice—a systematic review. Brain Cogn 108:32–41
    [Google Scholar]
  66. Goyal M, Singh S, Sibinga EMS, Gould NF, Rowland-Seymour A et al. 2014. Meditation programs for psychological stress and well-being: a systematic review and meta-analysis. JAMA Intern. Med. 174:3357–68
    [Google Scholar]
  67. Greenberg J, Shapero BG, Mischoulon D, Lazar SW 2017. Mindfulness-based cognitive therapy for depressed individuals improves suppression of irrelevant mental-sets. Eur. Arch. Psychiatry Clin. Neurosci. 267:3277–82
    [Google Scholar]
  68. Grossman P 2008. On measuring mindfulness in psychosomatic and psychological research. J. Psychosom. Res. 64:4405–8
    [Google Scholar]
  69. Grossman P, Van Dam NT 2011. Mindfulness, by any other name…: trials and tribulations of sati in western psychology and science. Contemp. Buddhism 12:1219–39
    [Google Scholar]
  70. Gu J, Strauss C, Bond R, Cavanagh K 2015. How do mindfulness-based cognitive therapy and mindfulness-based stress reduction improve mental health and wellbeing? A systematic review and meta-analysis of mediation studies. Clin. Psychol. Rev. 37:1–12
    [Google Scholar]
  71. Gustafson DH, McTavish FM, Chih M-Y, Atwood AK, Johnson RA et al. 2014. A smartphone application to support recovery from alcoholism: a randomized clinical trial. JAMA Psychiatry 71:5566–72
    [Google Scholar]
  72. Haase L, Thom NJ, Shukla A, Davenport PW, Simmons AN et al. 2016. Mindfulness-based training attenuates insula response to an aversive interoceptive challenge. Soc. Cogn. Affect. Neurosci. 11:1182–90
    [Google Scholar]
  73. Harrington A, Dunne JD 2015. When mindfulness is therapy: ethical qualms, historical perspectives. Am. Psychol. 70:7621–31Reviews historical developments that led to the integration of mindfulness practices into mental health treatment.
    [Google Scholar]
  74. Hayes SC, Luoma JB, Bond FW, Masuda A, Lillis J 2006. Acceptance and Commitment Therapy: model, processes and outcomes. Behav. Res. Ther. 44:11–25
    [Google Scholar]
  75. Hedman-Lagerlöf M, Hedman-Lagerlöf E, Öst L-G 2018. The empirical support for mindfulness-based interventions for common psychiatric disorders: a systematic review and meta-analysis. Psychol. Med. 48:132116–29
    [Google Scholar]
  76. Hepark S, Janssen L, de Vries A, Schoenberg PLA, Donders R et al. 2019. The efficacy of adapted MBCT on core symptoms and executive functioning in adults with ADHD: a preliminary randomized controlled trial. J. Atten. Disord 23:4351–62
    [Google Scholar]
  77. Hilton L, Hempel S, Ewing BA, Apaydin E, Xenakis L et al. 2017. Mindfulness meditation for chronic pain: systematic review and meta-analysis. Ann. Behav. Med. 51:2199–213
    [Google Scholar]
  78. Hofmann SG, Grossman P, Hinton DE 2011. Loving-kindness and compassion meditation: potential for psychological interventions. Clin. Psychol. Rev. 31:71126–32
    [Google Scholar]
  79. Hoge EA, Bui E, Goetter E, Robinaugh DJ, Ojserkis RA et al. 2015. Change in decentering mediates improvement in anxiety in Mindfulness-Based Stress Reduction for generalized anxiety disorder. Cogn. Ther. Res. 39:2228–35
    [Google Scholar]
  80. Hoge EA, Bui E, Marques L, Metcalf CA, Morris LK et al. 2013. Randomized controlled trial of mindfulness meditation for generalized anxiety disorder: effects on anxiety and stress reactivity. J. Clin. Psychiatry 74:8786–92
    [Google Scholar]
  81. Hölzel BK, Hoge EA, Greve DN, Gard T, Creswell JD et al. 2013. Neural mechanisms of symptom improvements in generalized anxiety disorder following mindfulness training. NeuroImage Clin 2:448–58
    [Google Scholar]
  82. Hölzel BK, Lazar SW, Gard T, Schuman-Olivier Z, Vago DR, Ott U 2011. How does mindfulness meditation work? Proposing mechanisms of action from a conceptual and neural perspective. Perspect. Psychol. Sci. 6:6537–59
    [Google Scholar]
  83. Hopwood TL, Schutte NS 2017. A meta-analytic investigation of the impact of mindfulness-based interventions on post traumatic stress. Clin. Psychol. Rev. 57:12–20
    [Google Scholar]
  84. Imel ZE, Laska K, Jakupcak M, Simpson TL 2013. Meta-analysis of dropout in treatments for posttraumatic stress disorder. J. Consult. Clin. Psychol. 81:3394–404
    [Google Scholar]
  85. Insel TR, Cuthbert B, Garvey M, Heinssen R, Pine DS et al. 2010. Research Domain Criteria (RDoC): toward a new classification framework for research on mental disorders. Am. J. Psychiatry 167:7748–51
    [Google Scholar]
  86. Jha AP, Morrison AB, Dainer-Best J, Parker S, Rostrup N, Stanley EA 2015. Minds “at attention”: mindfulness training curbs attentional lapses in military cohorts. PLOS ONE 10:2e0116889
    [Google Scholar]
  87. Jha AP, Stanley EA, Kiyonaga A, Wong L, Gelfand L 2010. Examining the protective effects of mindfulness training on working memory capacity and affective experience. Emotion 10:154–64
    [Google Scholar]
  88. Kabat-Zinn J 1990. Full Catastrophe Living New York: Delacorte Press
    [Google Scholar]
  89. Kabat-Zinn J 2011. Some reflections on the origins of MBSR, skillful means, and the trouble with maps. Contemp. Buddhism 12:1281–306
    [Google Scholar]
  90. Kabat-Zinn J, Lipworth L, Burney R 1985. The clinical use of mindfulness meditation for the self-regulation of chronic pain. J. Behav. Med. 8:2163–90
    [Google Scholar]
  91. Kabat-Zinn J, Massion AO, Kristeller J, Peterson LG, Fletcher KE et al. 1992. Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders. Am. J. Psychiatry 149:7936–71
    [Google Scholar]
  92. Khalsa SS, Rudrauf D, Damasio AR, Davidson RJ, Lutz A, Tranel D 2008. Interoceptive awareness in experienced meditators. Psychophysiology 45:4671–77
    [Google Scholar]
  93. Khoury B, Knäuper B, Schlosser M, Carrière K, Chiesa A 2017. Effectiveness of traditional meditation retreats: a systematic review and meta-analysis. J. Psychosom. Res. 92:16–25
    [Google Scholar]
  94. King AP, Block SR, Sripada RK, Rauch SAM, Giardino N et al. 2016a. Altered default mode network (DMN) resting state functional connectivity following a mindfulness-based exposure therapy for posttraumatic stress disorder (PTSD) in combat veterans of Afghanistan and Iraq. Depress. Anxiety 33:4289–99
    [Google Scholar]
  95. King AP, Block SR, Sripada RK, Rauch SAM, Porter KE et al. 2016b. A pilot study of mindfulness-based exposure therapy in OEF/OIF combat veterans with PTSD: altered medial frontal cortex and amygdala responses in social–emotional processing. Front. Psychiatry 7:154
    [Google Scholar]
  96. King AP, Favorite TK 2016. Mindfulness-Based Cognitive Therapy for combat-related posttraumatic stress disorder. Mindfulness-Based Cognitive Therapy: Innovative Applications SJ Eisendrath 163–91 Cham, Switz.: Springer
    [Google Scholar]
  97. Kirby JN 2017. Compassion interventions: the programmes, the evidence, and implications for research and practice. Psychol. Psychother. 90:3432–55
    [Google Scholar]
  98. Kirk U, Brown KW, Downar J 2015. Adaptive neural reward processing during anticipation and receipt of monetary rewards in mindfulness meditators. Soc. Cogn. Affect. Neurosci. 10:5752–59
    [Google Scholar]
  99. Kober H, Brewer JA, Height KL, Sinha R 2017. Neural stress reactivity relates to smoking outcomes and differentiates between mindfulness and cognitive–behavioral treatments. NeuroImage 151:4–13
    [Google Scholar]
  100. Kocovski NL, Fleming JE, Hawley LL, Huta V, Antony MM 2013. Mindfulness and acceptance-based group therapy versus traditional cognitive behavioral group therapy for social anxiety disorder: a randomized controlled trial. Behav. Res. Ther. 51:12889–98
    [Google Scholar]
  101. Koob GF, Volkow ND 2016. Neurobiology of addiction: a neurocircuitry analysis. Lancet Psychiatry 3:8760–73
    [Google Scholar]
  102. Kral TRA, Schuyler BS, Mumford JA, Rosenkranz MA, Lutz A, Davidson RJ 2018. Impact of short- and long-term mindfulness meditation training on amygdala reactivity to emotional stimuli. NeuroImage 181:301–13
    [Google Scholar]
  103. Kristeller JL, Wolever RQ 2010. Mindfulness-based eating awareness training for treating binge eating disorder: the conceptual foundation. Eat. Disord. 19:149–61
    [Google Scholar]
  104. Kristeller JL, Wolever RQ, Sheets V 2014. Mindfulness-based eating awareness training (MB-EAT) for binge eating: a randomized clinical trial. Mindfulness 5:3282–97
    [Google Scholar]
  105. Kross E, Gard D, Deldin P, Clifton J, Ayduk O 2012. “Asking why” from a distance: its cognitive and emotional consequences for people with major depressive disorder. J. Abnorm. Psychol. 121:3559–69
    [Google Scholar]
  106. Kuyken W, Hayes R, Barrett B, Byng R, Dalgleish T et al. 2015. Effectiveness and cost-effectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse or recurrence (PREVENT): a randomised controlled trial. Lancet 386:998863–73
    [Google Scholar]
  107. Kuyken W, Warren FC, Taylor RS, Whalley B, Crane C et al. 2016. Efficacy of mindfulness-based cognitive therapy in prevention of depressive relapse: an individual patient data meta-analysis from randomized trials. JAMA Psychiatry 73:6565–74
    [Google Scholar]
  108. Lao S-A, Kissane D, Meadows G 2016. Cognitive effects of MBSR/MBCT: a systematic review of neuropsychological outcomes. Conscious. Cogn. 45:109–23Reviews effects of mindfulness meditation training on core cognitive functions.
    [Google Scholar]
  109. Lau MA, Bishop SR, Segal ZV, Buis T, Anderson ND et al. 2006. The Toronto Mindfulness Scale: development and validation. J. Clin. Psychol. 62:121445–67
    [Google Scholar]
  110. Li W, Howard MO, Garland EL, McGovern P, Lazar M 2017. Mindfulness treatment for substance misuse: a systematic review and meta-analysis. J. Subst. Abuse Treat. 75:62–96
    [Google Scholar]
  111. Lin Y, Callahan CP, Moser JS 2018. A mind full of self: self-referential processing as a mechanism underlying the therapeutic effects of mindfulness training on internalizing disorders. Neurosci. Biobehav. Rev. 92:172–86
    [Google Scholar]
  112. Lindahl JR, Fisher NE, Cooper DJ, Rosen RK, Britton WB 2017. The varieties of contemplative experience: a mixed-methods study of meditation-related challenges in Western Buddhists. PLOS ONE 12:5e0176239
    [Google Scholar]
  113. Linehan MM 1993. Cognitive–Behavioral Treatment of Borderline Personality Disorder New York: Guilford Press
    [Google Scholar]
  114. Lutz A, Brefczynski-Lewis J, Johnstone T, Davidson RJ 2008a. Regulation of the neural circuitry of emotion by compassion meditation: effects of meditative expertise. PLOS ONE 3:3e1897
    [Google Scholar]
  115. Lutz A, Dunne JD, Davidson RJ 2007. Meditation and the neuroscience of consciousness: an introduction. The Cambridge Handbook of Consciousness PD Zelazo, M Moscovitch, E Thompson 499–551 New York: Cambridge Univ. Press
    [Google Scholar]
  116. Lutz A, Jha AP, Dunne JD, Saron CD 2015. Investigating the phenomenological matrix of mindfulness-related practices from a neurocognitive perspective. Am. Psychol. 70:7632–58Characterizes capacities targeted by MM, their neurobiological basis, and their relation to contemplative sources.
    [Google Scholar]
  117. Lutz A, McFarlin DR, Perlman DM, Salomons TV, Davidson RJ 2013. Altered anterior insula activation during anticipation and experience of painful stimuli in expert meditators. NeuroImage 64:538–46
    [Google Scholar]
  118. Lutz A, Slagter HA, Dunne JD, Davidson RJ 2008b. Attention regulation and monitoring in meditation. Trends Cogn. Sci. 12:4163–69
    [Google Scholar]
  119. Lynch TR, Trost WT, Salsman N, Linehan MM 2007. Dialectical behavior therapy for borderline personality disorder. Annu. Rev. Clin. Psychol. 3:181–205
    [Google Scholar]
  120. Mani M, Kavanagh DJ, Hides L, Stoyanov SR 2015. Review and evaluation of mindfulness-based iPhone apps. JMIR MHealth UHealth 3:3e82
    [Google Scholar]
  121. Mason AE, Epel ES, Aschbacher K, Lustig RH, Acree M et al. 2016. Reduced reward-driven eating accounts for the impact of a mindfulness-based diet and exercise intervention on weight loss: data from the SHINE randomized controlled trial. Appetite 100:86–93
    [Google Scholar]
  122. McNally RJ 2007. Mechanisms of exposure therapy: how neuroscience can improve psychological treatments for anxiety disorders. Clin. Psychol. Rev. 27:6750–59
    [Google Scholar]
  123. Miloyan B, Pachana NA, Suddendorf T 2014. The future is here: a review of foresight systems in anxiety and depression. Cogn. Emot. 28:5795–810
    [Google Scholar]
  124. Mitchell JT, McIntyre EM, English JS, Dennis MF, Beckham JC, Kollins SH 2017. A pilot trial of mindfulness meditation training for ADHD in adulthood: impact on core symptoms, executive functioning, and emotion dysregulation. J. Atten. Disord. 21:131105–20
    [Google Scholar]
  125. Mrazek MD, Mooneyham BW, Schooler JW 2014. Insights from quiet minds: the converging fields of mindfulness and mind-wandering. Meditation—Neuroscientific Approaches and Philosophical Implications 2 S Schmidt, H Walach 227–41 Cham, Switz.: Springer
    [Google Scholar]
  126. Munder T, Brütsch O, Leonhart R, Gerger H, Barth J 2013. Researcher allegiance in psychotherapy outcome research: an overview of reviews. Clin. Psychol. Rev. 33:4501–11
    [Google Scholar]
  127. Murray G, Leitan ND, Thomas N, Michalak EE, Johnson SL et al. 2017. Towards recovery-oriented psychosocial interventions for bipolar disorder: quality of life outcomes, stage-sensitive treatments, and mindfulness mechanisms. Clin. Psychol. Rev. 52:148–63
    [Google Scholar]
  128. Nahum-Shani I, Smith SN, Spring BJ, Collins LM, Witkiewitz K et al. 2018. Just-in-time adaptive interventions (JITAIs) in mobile health: key components and design principles for ongoing health behavior support. Ann. Behav. Med. 52:6446–62
    [Google Scholar]
  129. NICE (Natl. Institute Health Care Excell.). 2018. Depression in adults: recognition and management. Clin. Guide. 90, NICE, London, UK. https://www.nice.org.uk/guidance/cg90
  130. Niles BL, Klunk-Gillis J, Ryngala DJ, Silberbogen AK, Paysnick A, Wolf EJ 2012. Comparing mindfulness and psychoeducation treatments for combat-related PTSD using a telehealth approach. Psychol. Trauma 4:538–47
    [Google Scholar]
  131. Parsons CE, Crane C, Parsons LJ, Fjorback LO, Kuyken W 2017. Home practice in mindfulness-based cognitive therapy and mindfulness-based stress reduction: a systematic review and meta-analysis of participants’ mindfulness practice and its association with outcomes. Behav. Res. Ther. 95:29–41
    [Google Scholar]
  132. Perlman DM, Salomons TV, Davidson RJ, Lutz A 2010. Differential effects on pain intensity and unpleasantness of two meditation practices. Emotion 10:165–71
    [Google Scholar]
  133. Phelps EA, Delgado MR, Nearing KI, LeDoux JE 2004. Extinction learning in humans: role of the amygdala and vmPFC. Neuron 43:6897–905
    [Google Scholar]
  134. Quaglia JT, Brown KW, Lindsay EK, Creswell JD, Goodman RJ 2015. From conceptualization to operationalization of mindfulness. Handbook of Mindfulness: Theory, Research, and Practice KW Brown, JD Creswell, RM Ryan 151–170 New York: Guilford Press
    [Google Scholar]
  135. Rogers JM, Ferrari M, Mosely K, Lang CP, Brennan L 2017. Mindfulness-based interventions for adults who are overweight or obese: a meta-analysis of physical and psychological health outcomes. Obes. Rev. 18:151–67
    [Google Scholar]
  136. Rosenkranz MA, Davidson RJ, MacCoon DG, Sheridan JF, Kalin NH, Lutz A 2013. A comparison of mindfulness-based stress reduction and an active control in modulation of neurogenic inflammation. Brain. Behav. Immun. 27:174–84
    [Google Scholar]
  137. Ruffault A, Czernichow S, Hagger MS, Ferrand M, Erichot N et al. 2017. The effects of mindfulness training on weight-loss and health-related behaviours in adults with overweight and obesity: a systematic review and meta-analysis. Obes. Res. Clin. Pract. 11:590–111
    [Google Scholar]
  138. Santorelli SF 2014. Mindfulness-Based Stress Reduction (MBSR): Standards of Practice Worcester, MA: Cent. Mindfulness Med. Health Care Soc. Rev. ed.
    [Google Scholar]
  139. Santorelli SF, Meleo-Meyer F, Koerbel L, Kabat-Zinn J 2017. Mindfulness-Based Stress Reduction (MBSR) Authorized Curriculum Guide Worcester, MA: Cent. Mindfulness Med. Health Care Soc. Rev. ed.
    [Google Scholar]
  140. Schooler JW, Smallwood J, Christoff K, Handy TC, Reichle ED, Sayette MA 2011. Meta-awareness, perceptual decoupling and the wandering mind. Trends Cogn. Sci. 15:7319–26
    [Google Scholar]
  141. Segal ZV, Williams JMG, Teasdale JD 2002. Mindfulness-Based Cognitive Therapy for Depression: A New Approach to Preventing Relapse New York: Guilford Press
    [Google Scholar]
  142. Spijkerman MPJ, Pots WTM, Bohlmeijer ET 2016. Effectiveness of online mindfulness-based interventions in improving mental health: a review and meta-analysis of randomised controlled trials. Clin. Psychol. Rev. 45:102–14
    [Google Scholar]
  143. Suddendorf T, Corballis MC 2007. The evolution of foresight: What is mental time travel, and is it unique to humans?. Behav. Brain Sci. 30:3299–313
    [Google Scholar]
  144. Tang Y-Y, Hölzel BK, Posner MI 2015. The neuroscience of mindfulness meditation. Nat. Rev. Neurosci. 16:4213–25Detailed review of neuroimaging and other neurobiological findings associated with mindfulness meditation.
    [Google Scholar]
  145. Tang Y-Y, Tang R, Posner MI 2016. Mindfulness meditation improves emotion regulation and reduces drug abuse. Drug Alcohol Depend 163:Suppl. 1S13–18
    [Google Scholar]
  146. Tapper K 2018. Mindfulness and craving: effects and mechanisms. Clin. Psychol. Rev. 59:101–17
    [Google Scholar]
  147. Teasdale JD, Chaskalson M 2011a. How does mindfulness transform suffering? I: The nature and origins of dukkha. Contemp. . Buddhism 12:189–102
    [Google Scholar]
  148. Teasdale JD, Chaskalson M 2011b. How does mindfulness transform suffering? II: The transformation of dukkha. Contemp. . Buddhism 12:1103–24
    [Google Scholar]
  149. Thanissaro Bhikkhu, transl 1997. Sallatha sutta: the arrow. Access to Insight https://www.accesstoinsight.org/tipitaka/sn/sn36/sn36.006.than.html
    [Google Scholar]
  150. Tovote KA, Fleer J, Snippe E, Peeters AC, Emmelkamp PM et al. 2014. Individual mindfulness-based cognitive therapy and cognitive behavior therapy for treating depressive symptoms in patients with diabetes: results of a randomized controlled trial. Diabetes Care 37:92427–34
    [Google Scholar]
  151. Vago DR, Silbersweig DA 2012. Self-awareness, self-regulation, and self-transcendence (S-ART): a framework for understanding the neurobiological mechanisms of mindfulness. Front. Hum. Neurosci. 6:296
    [Google Scholar]
  152. Van Dam NT, van Vugt MK, Vago DR, Schmalzl L, Saron CD et al. 2018. Mind the hype: a critical evaluation and prescriptive agenda for research on mindfulness and meditation. Perspect. Psychol. Sci. 13:36–71
    [Google Scholar]
  153. van der Velden AM, Kuyken W, Wattar U, Crane C, Pallesen KJ et al. 2015. A systematic review of mechanisms of change in mindfulness-based cognitive therapy in the treatment of recurrent major depressive disorder. Clin. Psychol. Rev. 37:26–39
    [Google Scholar]
  154. Vettese LC, Toneatto T, Stea JN, Nguyen L, Wang JJ 2009. Do mindfulness meditation participants do their homework? And does it make a difference? A review of the empirical evidence. J. Cogn. Psychother. 23:3198–225
    [Google Scholar]
  155. Waldron EM, Hong S, Moskowitz JT, Burnett-Zeigler I 2018. A systematic review of the demographic characteristics of participants in US-based randomized controlled trials of mindfulness-based interventions. Mindfulness 2018:1–22
    [Google Scholar]
  156. Wampold BE, Imel ZE 2015. The Great Psychotherapy Debate: The Evidence for What Makes Psychotherapy Work New York: Routledge
    [Google Scholar]
  157. Wang L-Q, Chien WT, Yip LK, Karatzias T 2016. A randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up. Neuropsychiatr. Dis. Treat. 12:3097–3110
    [Google Scholar]
  158. Watkins ER 2008. Constructive and unconstructive repetitive thought. Psychol. Bull. 134:2163–206
    [Google Scholar]
  159. Webb CA, DeRubeis RJ, Barber JP 2010. Therapist adherence/competence and treatment outcome: a meta-analytic review. J. Consult. Clin. Psychol. 78:2200–211
    [Google Scholar]
  160. Westbrook C, Creswell JD, Tabibnia G, Julson E, Kober H, Tindle HA 2013. Mindful attention reduces neural and self-reported cue-induced craving in smokers. Soc. Cogn. Affect. Neurosci. 8:173–84
    [Google Scholar]
  161. Williams JMG, Teasdale JD, Segal ZV, Soulsby J 2000. Mindfulness-based cognitive therapy reduces overgeneral autobiographical memory in formerly depressed patients. J. Abnorm. Psychol. 109:1150–55
    [Google Scholar]
  162. Woods-Giscombé CL, Black AR 2010. Mind–body interventions to reduce risk for health disparities related to stress and strength among African American women: the potential of mindfulness-based stress reduction, loving-kindness, and the NTU therapeutic framework. Complement. Health Pract. Rev. 15:3115–31
    [Google Scholar]
  163. Yulish NE, Goldberg SB, Frost ND, Abbas M, Oleen-Junk NA et al. 2017. The importance of problem-focused treatments: a meta-analysis of anxiety treatments. Psychotherapy 54:4321–38
    [Google Scholar]
  164. Zeidan F, Adler-Neal AL, Wells RE, Stagnaro E, May LM et al. 2016. Mindfulness-meditation-based pain relief is not mediated by endogenous opioids. J. Neurosci. 36:113391–97
    [Google Scholar]
  165. Zeidan F, Emerson NM, Farris SR, Ray JN, Jung Y et al. 2015. Mindfulness meditation–based pain relief employs different neural mechanisms than placebo and sham mindfulness meditation–induced analgesia. J. Neurosci. 35:4615307–25
    [Google Scholar]
  166. Zeidan F, Martucci KT, Kraft RA, McHaffie JG, Coghill RC 2014. Neural correlates of mindfulness meditation–related anxiety relief. Soc. Cogn. Affect. Neurosci. 9:6751–59
    [Google Scholar]
  167. Zeidan F, Vago DR 2016. Mindfulness meditation–based pain relief: a mechanistic account. Ann. N. Y. Acad. Sci. 1373:1114–27
    [Google Scholar]
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