1932

Abstract

Evidence suggests that adjunctive psychosocial intervention for the treatment of pediatric bipolar spectrum disorders (BPSDs) is effective, feasible, and highly accepted as both an acute and maintenance treatment for youth with BPSD diagnoses as well as a preventive treatment for high-risk youth who are either asymptomatic or exhibit subsyndromal mood symptoms. Here, we provide a comprehensive review of all known evidence-based interventions, including detailed descriptions of treatment targets and core components, results of clinical trials, and updated research on mediators and moderators of treatment efficacy. Treatments are presented systematically according to level of empirical support (i.e., well established, probably efficacious, possibly efficacious, experimental, or questionable); upcoming and ongoing trials are included when possible. In line with a staging approach, preventive interventions are presented separately. Recommendations for best practices based on age, stage, and additional evidence-based child and family factors shown to affect treatment outcomes are provided.

Loading

Article metrics loading...

/content/journals/10.1146/annurev-clinpsy-072220-021237
2022-05-09
2024-12-12
Loading full text...

Full text loading...

/deliver/fulltext/clinpsy/18/1/annurev-clinpsy-072220-021237.html?itemId=/content/journals/10.1146/annurev-clinpsy-072220-021237&mimeType=html&fmt=ahah

Literature Cited

  1. Axelson DA, Birmaher B, Strober MA, Goldstein BI, Ha W et al. 2011. Course of subthreshold bipolar disorder in youth: diagnostic progression from bipolar disorder not otherwise specified. J. Am. Acad. Child Adolesc. Psychiatry 50:101001–16 https://doi.org/10.1016/j.jaac.2011.07.005
    [Crossref] [Google Scholar]
  2. Baltasar-Tello I, Miguélez-Fernández C, Peñuelas-Calvo I, Carballo JJ. 2018. Ecological momentary assessment and mood disorders in children and adolescents: a systematic review. Curr. Psychiatry Rep. 20:66 https://doi.org/10.1007/s11920-018-0913-z
    [Crossref] [Google Scholar]
  3. Benarous X, Consoli A, Milhiet V, Cohen D. 2016. Early interventions for youths at high risk for bipolar disorder: a developmental approach. Eur. Child Adolesc. Psychiatry 25:3217–33 https://doi.org/10.1007/s00787-015-0773-6
    [Crossref] [Google Scholar]
  4. Berk M, Post R, Ratheesh A, Gliddon E, Singh A et al. 2017. Staging in bipolar disorder: from theoretical framework to clinical utility. World Psychiatry 16:3236–44 https://doi.org/10.1002/wps.20441
    [Crossref] [Google Scholar]
  5. Birmaher B, Axelson D, Monk K, Kalas C, Goldstein B et al. 2009. Lifetime psychiatric disorders in school-aged offspring of parents with bipolar disorder: the Pittsburgh Bipolar Offspring Study. Arch. Gen. Psychiatry 66:3287–96 https://doi.org/10.1001/archgenpsychiatry.2008.546
    [Crossref] [Google Scholar]
  6. Birmaher B, Gill MK, Axelson DA, Goldstein BI, Goldstein TR et al. 2014. Longitudinal trajectories and associated baseline predictors in youths with bipolar spectrum disorders. Am. J. Psychiatry 171:9990–99 https://doi.org/10.1176/appi.ajp.2014.13121577
    [Crossref] [Google Scholar]
  7. Birmaher B, Merranko JA, Goldstein TR, Gill MK, Goldstein BI et al. 2018. A risk calculator to predict the individual risk of conversion from subthreshold bipolar symptoms to bipolar disorder I or II in youth. J. Am. Acad. Child Adolesc. Psychiatry 57:10755–63 https://doi.org/10.1016/j.jaac.2018.05.023
    [Crossref] [Google Scholar]
  8. Boylan K, MacPherson HA, Fristad MA. 2013. Examination of disruptive behavior outcomes and moderation in a randomized psychotherapy trial for mood disorders. J. Am. Acad. Child Adolesc. Psychiatry 52:7699–708 https://doi.org/10.1016/j.jaac.2013.04.014
    [Crossref] [Google Scholar]
  9. Chia MF, Cotton S, Filia K, Phelan M, Conus P et al. 2019. Early intervention for bipolar disorder—do current treatment guidelines provide recommendations for the early stages of the disorder?. J. Affect. Disord. 257:669–77 https://doi.org/10.1016/j.jad.2019.07.062
    [Crossref] [Google Scholar]
  10. Cotton S, Kraemer KM, Sears RW, Strawn JR, Wasson RS et al. 2020. Mindfulness-based cognitive therapy for children and adolescents with anxiety disorders at-risk for bipolar disorder: a psychoeducation waitlist controlled pilot trial. Early Interv. Psychiatry. 14:2211–19 https://doi.org/10.1111/eip.12848
    [Crossref] [Google Scholar]
  11. Cotton S, Luberto CM, Sears RW, Strawn JR, Stahl L et al. 2016. Mindfulness-based cognitive therapy for youth with anxiety disorders at risk for bipolar disorder: a pilot trial. Early Interv. Psychiatry 10:5426–34 https://doi.org/10.1111/eip.12216
    [Crossref] [Google Scholar]
  12. Cotton SM, Berk M, Jackson H, Murray G, Filia K et al. 2019. Improving functional outcomes in early-stage bipolar disorder: the protocol for the REsearch into COgnitive and behavioural VERsatility trial. Early Interv. Psychiatry 13:61470–79 https://doi.org/10.1111/eip.12797
    [Crossref] [Google Scholar]
  13. Cummings CM, Fristad MA. 2012. Anxiety in children with mood disorders: a treatment help or hindrance?. J. Abnorm. Child Psychol. 40:3339–51 https://doi.org/10.1007/s10802-011-9568-5
    [Crossref] [Google Scholar]
  14. Danielson CK, Feeny NC, Findling RL, Youngstrom EA. 2004. Psychosocial treatment of bipolar disorders in adolescents: a proposed cognitive-behavioral intervention. Cogn. Behav. Pract. 11:3283–97 https://doi.org/10.1016/S1077-7229(04)80043-9
    [Crossref] [Google Scholar]
  15. Duffy A, Goodday S, Keown-Stoneman C, Grof P. 2019. The emergent course of bipolar disorder: observations over two decades from the Canadian high-risk offspring cohort. Am. J. Psychiatry 176:9720–29 https://doi.org/10.1176/appi.ajp.2018.18040461
    [Crossref] [Google Scholar]
/content/journals/10.1146/annurev-clinpsy-072220-021237
Loading
/content/journals/10.1146/annurev-clinpsy-072220-021237
Loading

Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error