Raising the superconducting transition temperature to a point where applications are practical is one of the most important challenges in science. In this review, we aim at gaining insights on the controlling factors for a particular high-temperature superconductor family—the FeSe-based superconductors. In particular, we discuss the mechanisms by which the Cooper pairing temperature is enhanced from ∼8 K in bulk FeSe to ∼80 K in the interface between an atomic layer of FeSe and SrTiO. This includes the experimental hints and the theoretical simulation of the involved mechanisms. We end by applying these insights to suggest some possible high-temperature superconducting systems.


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