
Full text loading...
Transcriptome analysis has been a key area of biological inquiry for decades. Over the years, research in the field has progressed from candidate gene-based detection of RNAs using Northern blotting to high-throughput expression profiling driven by the advent of microarrays. Next-generation sequencing technologies have revolutionized transcriptomics by providing opportunities for multidimensional examinations of cellular transcriptomes in which high-throughput expression data are obtained at a single-base resolution.
Article metrics loading...
Full text loading...
Data & Media loading...
Supplemental Figure 1. Decreasing error and increasing read lengths of the Illumina Genome Analyzer platform over the preceding 19 months. Average per base errors of 609 phiX174 control lanes are plotted in red. Error models were calculated by enumeration of miss-matches between sequence reads and the phiX174 reference genome. Read lengths of the corresponding runs are plotted in blue.
Download Supplemental Figure 1 as a PDF.