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Abstract

Transcriptome analysis has been a key area of biological inquiry for decades. Over the years, research in the field has progressed from candidate gene-based detection of RNAs using Northern blotting to high-throughput expression profiling driven by the advent of microarrays. Next-generation sequencing technologies have revolutionized transcriptomics by providing opportunities for multidimensional examinations of cellular transcriptomes in which high-throughput expression data are obtained at a single-base resolution.

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/content/journals/10.1146/annurev-genom-082908-145957
2009-09-22
2024-06-18
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Supplementary Data

  • Article Type: Review Article
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