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Abstract

RNA interference (RNAi) is a conserved eukaryotic gene regulatory mechanism that uses small noncoding RNAs to mediate posttranscriptional/transcriptional gene silencing. The fission yeast and the filamentous fungus have served as important model systems for RNAi research. Studies on these two organisms and other fungi have contributed significantly to our understanding of the mechanisms and functions of RNAi in eukaryotes. In addition, surprisingly diverse RNAi-mediated processes and small RNA biogenesis pathways have been discovered in fungi. In this review, we give an overview of different fungal RNAi pathways with a focus on their mechanisms and functions.

[Erratum, Closure]

An erratum has been published for this article:
RNA Interference Pathways in Fungi: Mechanisms and Functions
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/content/journals/10.1146/annurev-micro-092611-150138
2012-10-13
2024-06-17
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  • Article Type: Review Article
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