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Abstract
The chapter provides a personal and anecdotal account of the author's attempts to keep the horizons of advancing science in sight. It sketches his background to entering science and chronicles various episodes across fifty years in research. Milestones are noted on the author's journey from his structural studies on colchicine, griseofulvin, and gibberellic acid to the isolation, analysis, biosynthesis, and molecular biology of plant gibberellins. The author discusses his personal and professional interactions with plant physiologists and plant biochemists over the years. Philosophical observations are offered on some of the attributes important to conducting research and on changing attitudes toward research.