1932

Abstract

After half a century of success in combating infectious diseases with vaccination and antibiotics, emerging and reemerging epidemics present a new threat to human health. Meanwhile, the rapid pace of viral and microbial genomics research, largely based on the success of genomics technologies, offers new data-generating platforms and a revolutionary knowledge base for better understanding the diseases and the associated pathogens. Systematic molecular biology studies using genomics information and technologies have helped to elucidate mechanisms of virulence and pathogenicity, whereas genomics-based medical genetic studies have been used to better understand pathogen susceptibility. This progress may lead to the development of effective and safe vaccines in the future. Here we highlight the ongoing historical transition in the field of infectious disease research and clinical practice in the new era of genomics.

Keyword(s): bacteriapathogenvirus
Loading

Article metrics loading...

/content/journals/10.1146/annurev.genom.9.081307.164428
2008-09-22
2024-06-13
Loading full text...

Full text loading...

/content/journals/10.1146/annurev.genom.9.081307.164428
Loading
/content/journals/10.1146/annurev.genom.9.081307.164428
Loading

Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error