1932

Abstract

Collagenous and lymphocytic colitis are newly recognized causes of choric watery diarrhea that typically affect middle-aged patients. Although endoscopic studies are normal, inflammatory changes and (in the case of collagenous colitis) collagen deposition occur histologically in the colonic mucosa. The pathogenesis of these disorders remains a mystery, but the possible causes are intriguing. Patients may experience spontaneous remissions and relapses, but treatment with sulfasalazine or prednisone is usually effective for patients with distressing symptoms.

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/content/journals/10.1146/annurev.med.45.1.105
1994-02-01
2024-04-21
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  • Article Type: Review Article
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