1932

Abstract

Platelet aggregation is one of the best understood examples of adhesive cell-cell interactions. The platelet glycoprotein IIb/IIIa membrane receptor plays a pivotal role in platelet aggregation through its binding of fibrinogen. It is intimately involved in the pathogenesis of platelet-rich arterial thromboses. The IIb/IIIa receptor is an important target for recently described novel antiplatelet therapeutics. The development and clinical evaluation of this class of antiplatelet therapeutics are reviewed in this article.

Loading

Article metrics loading...

/content/journals/10.1146/annurev.med.46.1.257
1995-02-01
2024-12-10
Loading full text...

Full text loading...

/content/journals/10.1146/annurev.med.46.1.257
Loading
/content/journals/10.1146/annurev.med.46.1.257
Loading

Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error