1932

Abstract

is a member of the family that lives in a mutualistic association with a nematode worm. The nematode worm burrows into insect prey and regurgitates , which goes on to kill the insect. The nematode feeds off the growing bacteria until the insect tissues are exhausted, whereupon they reassociate and leave the cadaver in search of new prey. This highly efficient partnership has been used for many years as a biological crop protection agent. The dual nature of as a pathogen and mutualist makes it a superb model for understanding these apparently exclusive activities. Furthermore, recently identified clinical isolates of are helping us to understand how human pathogens can emerge from the enormous reservoir of invertebrate pathogens in the environment. As has never been found outside a host animal, its niche represents an entirely biotic landscape. In this review we discuss what molecular adaptations allow this bacterium to complete this fascinating and complex life cycle.

Keyword(s): immunityinsectsymbiosistoxinsvirulence
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/content/journals/10.1146/annurev.micro.091208.073507
2009-10-13
2024-04-13
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  • Article Type: Review Article
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