Tuberculosis (TB) has afflicted humankind throughout history. Approximately one third of the world's population is currently infected with and nearly two million people die of TB annually. Although much has been learned about the structure of the tubercle bacillus, the epidemiology of TB, the physiological and immunological responses of the host to infection, and the physiology of in laboratory broth cultures, much of the basic biology of in its natural setting (the infected human) remains to be elucidated. Within the past decade, there have been remarkable advances in the development of genetic and molecular biological tools with which to study . This review discusses the approaches that have been employed and the progress that has been made in discovering how has achieved its prowess as a successful pathogen.


Article metrics loading...

Loading full text...

Full text loading...


Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error