1932

Abstract

Adrenergic receptors are key targets within the autonomic nervous system, regulating a wide variety of physiological processes. The ability to modify adrenergic receptor expression patterns in vivo has added a powerful new tool to the functional analysis of these receptors. Modification of adrenergic receptor gene expression by overexpression, genetic ablation, or site-specific mutation has added new insight to models of receptor coupling behavior, pharmacology, and subtype-specific physiological function. This review highlights some of the recent advances resulting from such genetic approaches to the study of adrenergic receptors.

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/content/journals/10.1146/annurev.pharmtox.38.1.351
1998-04-01
2024-06-21
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/content/journals/10.1146/annurev.pharmtox.38.1.351
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  • Article Type: Review Article
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