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Annual Review of Medicine

Volume 67, 2016

Oral Immunotherapy for Peanut Allergy

Abstract

Peanut allergy is a common disease and the cause of severe, life-threatening allergic reactions and death. It is rarely outgrown; most pediatric patients carry the disease into adulthood. Peanut allergy poses a significant burden on the quality of life of sufferers and their families, which results mainly from the fear of accidental peanut ingestion but is also due to dietary and social restrictions. Current standard management involves avoidance advice, patient education, and provision of emergency rescue medication. Immunotherapy, commonly used to treat other allergic diseases, has shown promise as a disease-modifying therapy for peanut allergy. Results from studies of oral immunotherapy show high efficacy rates, improvement in quality of life, and a good safety profile. Treatment may result in sustained unresponsiveness in a proportion of patients, whereas others require ongoing treatment.

Keyword(s): anaphylaxis, challenge, desensitization, immunomodulators, immunotherapy, tolerance
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/content/journals/10.1146/annurev-med-061014-094943
2016-01-14
2024-04-26
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/content/journals/10.1146/annurev-med-061014-094943
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Oral Immunotherapy for Peanut Allergy
Annual Review of Medicine 67, 375 (2016); https://doi.org/10.1146/annurev-med-061014-094943
/content/journals/10.1146/annurev-med-061014-094943
/content/journals/10.1146/annurev-med-061014-094943
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  • Article Type: Review Article

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