1932
0
  1. Home
  2. A-Z Publications
  3. Annual Review of Plant Biology
  4. Volume 74, 2023
  5. Article

Annual Review of Plant Biology

Volume 74, 2023

BAHD Company: The Ever-Expanding Roles of the BAHD Acyltransferase Gene Family in Plants

Abstract

Plants’ ability to chemically modify core structures of specialized metabolites is the main reason why the plant kingdom contains such a wide and rich array of diverse compounds. One of the most important types of chemical modifications of small molecules is the addition of an acyl moiety to produce esters and amides. Large-scale phylogenomics analyses have shown that the enzymes that perform acyl transfer reactions on the myriad small molecules synthesized by plants belong to only a few gene families. This review is focused on describing the biochemistry, evolutionary origins, and chemical ecology implications of one of these families—the BAHD acyltransferases. The growth of advanced metabolomic studies coupled with next-generation sequencing of diverse plant species has confirmed that the BAHD family plays critical roles in modifying nearly all known classes of specialized metabolites. The current and future outlook for research on BAHDs includes expanding their roles in synthetic biology and metabolic engineering.

Keyword(s): acylsugars, amide, ester, HCT, hydroxycinnamoyltransferase, land plant evolution, phenylpropanoid
Loading

Article metrics loading...

/content/journals/10.1146/annurev-arplant-062922-050122
2023-05-22
2024-04-26
Loading full text...

Full text loading...

/deliver/fulltext/arplant/74/1/annurev-arplant-062922-050122.html?itemId=/content/journals/10.1146/annurev-arplant-062922-050122&mimeType=html&fmt=ahah

Literature Cited

  1. 1.
    Aharoni A, Keizer LCP, Bouwmeester HJ, Sun Z, Alvarez-Huerta M et al. 2000. Identification of the SAAT gene involved in strawberry flavor biogenesis by use of DNA microarrays. Plant Cell 12:647–61
     [Google Scholar]
  2. 2.
    Alexander LE, Okazaki Y, Schelling MA, Davis A, Zheng X et al. 2020. Maize Glossy2 and Glossy2-like genes have overlapping and distinct functions in cuticular lipid deposition. Plant Physiol 183:840–53
     [Google Scholar]
  3. 3.
    Alexander NJ, McCormick SP, Hohn TM. 2002. The identification of the Saccharomyces cerevisiae gene AYT1(ORF-YLL063c) encoding an acetyltransferase. Yeast 19:1425–30
     [Google Scholar]
  4. 4.
    Allmann S, Baldwin IT. 2010. Insects betray themselves in nature to predators by rapid isomerization of green leaf volatiles. Science 329:1075–78
     [Google Scholar]
  5. 5.
    Alseekh S, Perez de Souza L, Benina M, Fernie AR. 2020. The style and substance of plant flavonoid decoration; towards defining both structure and function. Phytochemistry 174:112347
     [Google Scholar]
  6. 6.
    Anders N, Wilkinson MD, Lovegrove A, Freeman J, Tryfona T et al. 2012. Glycosyl transferases in family 61 mediate arabinofuranosyl transfer onto xylan in grasses. PNAS 109:989–93
     [Google Scholar]
  7. 7.
    Andersen OM, Markham KR. 2005. Flavonoids Boca Raton, FL: CRC Press
  8. 8.
    Bai Y, Yang C, Halitschke R, Paetz C, Kessler D et al. 2022. Natural history-guided omics reveals plant defensive chemistry against leafhopper pests. Science 375:eabm2948
     [Google Scholar]
  9. 9.
    Bartley LE, Peck ML, Kim S-R, Ebert B, Manisseri C et al. 2013. Overexpression of a BAHD acyltransferase, OsAt10, alters rice cell wall hydroxycinnamic acid content and saccharification. Plant Physiol 161:1615–33
     [Google Scholar]
  10. 10.
    Berardi AE, Esfeld K, Jäggi L, Mandel T, Cannarozzi GM, Kuhlemeier C. 2021. Complex evolution of novel red floral color in Petunia. Plant Cell 33:2273–95
     [Google Scholar]
  11. 11.
    Berger A, Meinhard J, Petersen M. 2006. Rosmarinic acid synthase is a new member of the superfamily of BAHD acyltransferases. Planta 224:1503–10
     [Google Scholar]
  12. 12.
    Bird CR, Smith TA. 1982. Agmatine coumaroyltransferase, an enzyme involved in the formation of the antifungal hordatines in barley (Hordeum vulgare) seedlings. Biochem. Soc. Trans. 10:400–1
     [Google Scholar]
  13. 13.
    Boatright J, Negre F, Chen XL, Kish CM, Wood B et al. 2004. Understanding in vivo benzenoid metabolism in petunia petal tissue. Plant Physiol 135:1993–2011
     [Google Scholar]
  14. 14.
    Bontpart T, Cheynier V, Ageorges A, Terrier N. 2015. BAHD or SCPL acyltransferase? What a dilemma for acylation in the world of plant phenolic compounds. New Phytol 208:695–707
     [Google Scholar]
  15. 15.
    Bouchez P, Teixeira Benites V, Baidoo EEK, Mortimer JC, Sullivan ML et al. 2019. Production of clovamide and its analogues in Saccharomyces cerevisiae and Lactococcus lactis. Lett. Appl. Microbiol. 69:181–89
     [Google Scholar]
  16. 16.
    Cheng AX, Gou JY, Yu XH, Yang H, Fang X et al. 2013. Characterization and ectopic expression of a Populus hydroxyacid hydroxycinnamoyltransferase. Mol. Plant 6:1889–903
     [Google Scholar]
  17. 17.
    Chiang Y-C, Levsh O, Lam CK, Weng J-K, Wang Y. 2018. Structural and dynamic basis of substrate permissiveness in hydroxycinnamoyltransferase (HCT). PLOS Comput. Biol. 14:e1006511
     [Google Scholar]
  18. 18.
    Chiniquy D, Sharma V, Schultink A, Baidoo EE, Rautengarten C et al. 2012. XAX1 from glycosyltransferase family 61 mediates xylosyltransfer to rice xylan. PNAS 109:17117–22
     [Google Scholar]
  19. 19.
    Christiaens JF, Franco LM, Cools TL, De Meester L, Michiels J et al. 2014. The fungal aroma gene ATF1 promotes dispersal of yeast cells through insect vectors. Cell Rep 9:425–32
     [Google Scholar]
  20. 20.
    Ciarkowska A, Ostrowski M, Starzynska E, Jakubowska A. 2019. Plant SCPL acyltransferases: multiplicity of enzymes with various functions in secondary metabolism. Phytochem. Rev. 18:303–16
     [Google Scholar]
  21. 21.
    D'Auria JC. 2006. Acyltransferases in plants: a good time to be BAHD. Curr. Opin. Plant Biol. 9:331–40
     [Google Scholar]
  22. 22.
    D'Auria JC, Chen F, Pichersky E 2002. Characterization of an acyltransferase capable of synthesizing benzylbenzoate and other volatile esters in flowers and damaged leaves of Clarkia breweri. Plant Physiol 130:466–76
     [Google Scholar]
  23. 23.
    D'Auria JC, Pichersky E, Schaub A, Hansel A, Gershenzon J 2007. Characterization of a BAHD acyltransferase responsible for producing the green leaf volatile (Z)-3-hexen-1-yl acetate in Arabidopsis thaliana. Plant J 49:194–207
     [Google Scholar]
  24. 24.
    D'Auria JC, Reichelt M, Luck K, Svatos A, Gershenzon J. 2007. Identification and characterization of the BAHD acyltransferase malonyl CoA: Anthocyanidin 5-O-glucoside-6′′-O-malonyltransferase (At5MAT) in Arabidopsis thaliana. FEBS Lett 581:872–78
     [Google Scholar]
  25. 25.
    de Oliveira DM, Finger-Teixeira A, Mota TR, Salvador VH, Moreira-Vilar FC et al. 2015. Ferulic acid: a key component in grass lignocellulose recalcitrance to hydrolysis. Plant Biotechnol. J. 13:1224–32
     [Google Scholar]
  26. 26.
    Dexter R, Qualley A, Kish CM, Ma CJ, Koeduka T et al. 2007. Characterization of a petunia acetyltransferase involved in the biosynthesis of the floral volatile isoeugenol. Plant J 49:265–75
     [Google Scholar]
  27. 27.
    Dixon RA, Barros J. 2019. Lignin biosynthesis: old roads revisited and new roads explored. Open Biol 9:190215
     [Google Scholar]
  28. 28.
    Dobritzsch M, Lübken T, Eschen-Lippold L, Gorzolka K, Blum E et al. 2016. MATE transporter-dependent export of hydroxycinnamic acid amides. Plant Cell 28:583–96
     [Google Scholar]
  29. 29.
    Döring AS, Petersen M. 2014. Production of caffeic, chlorogenic and rosmarinic acids in plants and suspension cultures of Glechoma hederacea. Phytochem Lett 10:cxi–cxvii
     [Google Scholar]
  30. 30.
    Dudareva N, D'Auria JC, Nam KH, Raguso RA, Pichersky E 1998. Acetyl-CoA:benzylalcohol acetyltransferase—an enzyme involved in floral scent production in Clarkia breweri. Plant J 14:297–304
     [Google Scholar]
  31. 31.
    Eudes A, Mouille M, Robinson DS, Benites VT, Wang G et al. 2016. Exploiting members of the BAHD acyltransferase family to synthesize multiple hydroxycinnamate and benzoate conjugates in yeast. Microb. Cell Fact. 15:198Groundbreaking study for the field of BAHD metabolic engineering that used BAHD members to manipulate a host of benzenoid- and phenylpropanoid-containing esters and amides that could be used for pharmaceutical purposes.
     [Google Scholar]
  32. 32.
    Fan P, Leong BJ, Last RL. 2019. Tip of the trichome: evolution of acylsugar metabolic diversity in Solanaceae. Curr. Opin. Plant Biol. 49:8–16
     [Google Scholar]
  33. 33.
    Fan P, Miller AM, Liu X, Jones AD, Last RL. 2017. Evolution of a flipped pathway creates metabolic innovation in tomato trichomes through BAHD enzyme promiscuity. Nat. Commun. 8:2080
     [Google Scholar]
  34. 34.
    Fan P, Miller AM, Schilmiller AL, Liu XX, Ofner I et al. 2016. In vitro reconstruction and analysis of evolutionary variation of the tomato acylsucrose metabolic network. PNAS 113:E239–48
     [Google Scholar]
  35. 35.
    Fan P, Moghe GD, Last RL. 2016. Comparative biochemistry and in vitro pathway reconstruction as powerful partners in studies of metabolic diversity. Methods Enzymol 576:1–17
     [Google Scholar]
  36. 36.
    Fan P, Wang P, Lou Y-R, Leong BJ, Moore BM et al. 2020. Evolution of a plant gene cluster in Solanaceae and emergence of metabolic diversity. eLife 9:e56717
     [Google Scholar]
  37. 37.
    Feng H, Acosta-Gamboa L, Kruse LH, Tracy JD, Chung SH et al. 2021. Acylsugars protect Nicotiana benthamiana against insect herbivory and desiccation. Plant Mol. Biol. 109:505–22
     [Google Scholar]
  38. 38.
    Fich EA, Segerson NA, Rose JKC. 2016. The plant polyester cutin: biosynthesis, structure, and biological roles. Annu. Rev. Plant Biol. 67:207–33
     [Google Scholar]
  39. 39.
    Franke R, Schreiber L. 2007. Suberin—a biopolyester forming apoplastic plant interfaces. Curr. Opin. Plant Biol. 10:252–59
     [Google Scholar]
  40. 40.
    Fujii T, Nagasawa N, Iwamatsu A, Bogaki T, Tamai Y, Hamachi M. 1994. Molecular cloning, sequence analysis, and expression of the yeast alcohol acetyltransferase gene. Appl. Environ. Microbiol. 60:2786–92
     [Google Scholar]
  41. 41.
    Fujiwara H, Tanaka Y, Fukui Y, Nakao M, Ashikari T, Kusumi T. 1997. Anthocyanin 5-aromatic acyltransferase from Gentiana triflora: purification, characterization and its role in anthocyanin biosynthesis. Eur. J. Biochem. 249:45–51
     [Google Scholar]
  42. 42.
    Gaquerel E, Gulati J, Baldwin IT. 2014. Revealing insect herbivory-induced phenolamide metabolism: from single genes to metabolic network plasticity analysis. Plant J 79:679–92
     [Google Scholar]
  43. 43.
    Giusti MM, Wrolstad RE. 2003. Acylated anthocyanins from edible sources and their applications in food systems. Biochem. Eng. J. 14:217–25
     [Google Scholar]
  44. 44.
    Goldsmith M, Barad S, Knafo M, Savidor A, Ben-Dor S et al. 2022. Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea. J. Biol. Chem. 298:101806The combination of molecular docking and crystallography in this study made it possible to dissect the catalytic mechanism of β-ODAP synthase, paving the way for similar combinatorial studies with BAHDs.
     [Google Scholar]
  45. 45.
    Gonzales-Vigil E, vonLoessl ME, Chen JY, Li S, Haslam TM et al. 2021. Understanding the role of Populus ECERIFERUM2-likes in the biosynthesis of very-long-chain fatty acids for cuticular waxes. Plant Cell Physiol 62:827–38
     [Google Scholar]
  46. 46.
    Gou J-Y, Yu X-H, Liu C-J 2009. A hydroxycinnamoyltransferase responsible for synthesizing suberin aromatics in Arabidopsis. PNAS 106:18855–60
     [Google Scholar]
  47. 47.
    Goulet C, Kamiyoshihara Y, Lam NB, Richard T, Taylor MG et al. 2014. Divergence in the enzymatic activities of a tomato and Solanum pennellii alcohol acyltransferase impacts fruit volatile ester composition. Mol. Plant 8:153–62
     [Google Scholar]
  48. 48.
    Grienenberger E, Besseau S, Geoffroy P, Debayle D, Heintz D et al. 2009. A BAHD acyltransferase is expressed in the tapetum of Arabidopsis anthers and is involved in the synthesis of hydroxycinnamoyl spermidines. Plant J 58:246–59
     [Google Scholar]
  49. 49.
    Grienenberger E, Quilichini TD. 2021. The toughest material in the plant kingdom: an update on sporopollenin. Front. Plant Sci. 12:703864
     [Google Scholar]
  50. 50.
    Haslam TM, Gerelle WK, Graham SW, Kunst L 2017. The unique role of the ECERIFERUM2-LIKE clade of the BAHD acyltransferase superfamily in cuticular wax metabolism. Plants 6:23
     [Google Scholar]
  51. 51.
    Haslam TM, Haslam R, Thoraval D, Pascal S, Delude C et al. 2015. ECERIFERUM2-LIKE proteins have unique biochemical and physiological functions in very-long-chain fatty acid elongation. Plant Physiol 167:682–92
     [Google Scholar]
  52. 52.
    Haslam TM, Manas-Fernandez A, Zhao LF, Kunst L. 2012. Arabidopsis ECERIFERUM2 is a component of the fatty acid elongation machinery required for fatty acid extension to exceptional lengths. Plant Physiol 160:1164–74
     [Google Scholar]
  53. 53.
    Hoffmann L, Besseau S, Geoffroy P, Ritzenthaler C, Meyer D et al. 2004. Silencing of hydroxycinnamoyl-coenzyme A shikimate/quinate hydroxycinnamoyltransferase affects phenylpropanoid biosynthesis. Plant Cell 16:1446–65
     [Google Scholar]
  54. 54.
    Hoffmann L, Maury S, Martz F, Geoffroy P, Legrand M. 2003. Purification, cloning, and properties of an acyltransferase controlling shikimate and quinate ester intermediates in phenylpropanoid metabolism. J. Biol. Chem. 278:95–103The first article to show the importance of a BAHD hydroxycinnamoyltransferase [in combination with a CYP98 monooxygenase described by Schoch et al. 2001 (132)] in the formation of monolignols, which are the basis for lignin formation and thus land plant evolution.
     [Google Scholar]
  55. 55.
    Holland D, Larkov O, Bar-Ya'akov I, Bar E, Zax A et al. 2005. Developmental and varietal differences in volatile ester formation and acetyl-CoA: alcohol acetyl transferase activities in apple (Malus domestica Borkh.) fruit. J. Agric. Food. Chem. 53:7198–203
     [Google Scholar]
  56. 56.
    Irmisch S, Jo S, Roach CR, Jancsik S, Saint Yuen MM et al. 2018. Discovery of UDP-glycosyltransferases and BAHD-acyltransferases involved in the biosynthesis of the antidiabetic plant metabolite montbretin A. Plant Cell 30:1864–86
     [Google Scholar]
  57. 57.
    Ishihara A, Matsukawa T, Miyagawa H, Ueno T, Mayama S, Iwamura H. 1997. Induction of hydroxycinnamoyl-CoA:hydroxyanthranilate N-hydroxycinnamoyltransferase (HHT) activity in oat leaves by victorin C. Z. Naturforsch. 52c:756–60
     [Google Scholar]
  58. 58.
    Ishihara H, Tohge T, Viehöver P, Fernie AR, Weisshaar B, Stracke R. 2016. Natural variation in flavonol accumulation in Arabidopsis is determined by the flavonol glucosyltransferase BGLU6. J. Exp. Bot. 67:1505–17
     [Google Scholar]
  59. 59.
    Jetter R, Kunst L, Samuels AL. 2008. Composition of plant cuticular waxes. Biol. Plant Cuticle 23:145–81
     [Google Scholar]
  60. 60.
    Jiao C, Sørensen I, Sun X, Sun H, Behar H et al. 2020. The Penium margaritaceum genome: hallmarks of the origins of land plants. Cell 181:1097–111.e12
     [Google Scholar]
  61. 61.
    Karlen SD, Free HC, Padmakshan D, Smith BG, Ralph J, Harris PJ 2018. Commelinid monocotyledon lignins are acylated by p-coumarate. Plant Physiol 177:513–21
     [Google Scholar]
  62. 62.
    Karlen SD, Zhang C, Peck ML, Smith RA, Padmakshan D et al. 2016. Monolignol ferulate conjugates are naturally incorporated into plant lignins. Sci. Adv. 2:e1600393
     [Google Scholar]
  63. 63.
    Kessler D, Diezel C, Clark DG, Colquhoun TA, Baldwin IT. 2013. Petunia flowers solve the defence/apparency dilemma of pollinator attraction by deploying complex floral blends. Ecol. Lett. 16:299–306
     [Google Scholar]
  64. 64.
    Kim B-G, Jung WD, Mok H, Ahn J-H. 2013. Production of hydroxycinnamoyl-shikimates and chlorogenic acid in Escherichia coli: production of hydroxycinnamic acid conjugates. Microb. Cell Fact. 12:15
     [Google Scholar]
  65. 65.
    Kim J, Kang K, Gonzales-Vigil E, Shi F, Jones AD et al. 2012. Striking natural diversity in glandular trichome acylsugar composition is shaped by variation at the Acyltransferase2 locus in the wild tomato Solanum habrochaites. Plant Physiol 160:1854–70
     [Google Scholar]
  66. 66.
    Koornneef M, Hanhart CJ, Thiel F. 1989. A genetic and phenotypic description of Eceriferum (cer) mutants in Arabidopsis thaliana. J. Hered. 80:118–22
     [Google Scholar]
  67. 67.
    Korenblum E, Dong Y, Szymanski J, Panda S, Jozwiak A et al. 2020. Rhizosphere microbiome mediates systemic root metabolite exudation by root-to-root signaling. PNAS 117:3874–83
     [Google Scholar]
  68. 68.
    Kriegshauser L, Knosp S, Grienenberger E, Tatsumi K, Gütle DD et al. 2021. Function of the HYDROXYCINNAMOYL-CoA:SHIKIMATE HYDROXYCINNAMOYL TRANSFERASE is evolutionarily conserved in embryophytes. Plant Cell 33:1472–91Shows that the fundamental activity of HST already emerged in bryophytes, highlighting its importance for the colonization of land plants and later lignin biosynthesis.
     [Google Scholar]
  69. 69.
    Kruse LH, Bennett AA, Mahood EH, Lazarus E, Park SJ et al. 2022. Illuminating the lineage-specific diversification of resin glycoside acylsugars in the morning glory (Convolvulaceae) family using computational metabolomics. Hortic. Res. 9:uhab079
     [Google Scholar]
  70. 70.
    Kruse LH, Weigle AT, Irfan M, Martínez-Gómez J, Chobirko JD et al. 2022. Orthology-based analysis helps map evolutionary diversification and predict substrate class use of BAHD acyltransferases. Plant J 111:1453–68
     [Google Scholar]
  71. 71.
    Kulagina N, Méteignier L-V, Papon N, O'Connor SE, Courdavault V. 2022. More than a Catharanthus plant: A multicellular and pluri-organelle alkaloid-producing factory. Curr. Opin. Plant Biol. 67:102200
     [Google Scholar]
  72. 72.
    Lallemand LA, McCarthy JG, McSweeney S, McCarthy AA. 2012. Purification, crystallization and preliminary X-ray diffraction analysis of a hydroxycinnamoyl-CoA shikimate/quinate hydroxycinnamoyltransferase (HCT) from Coffea canephora involved in chlorogenic acid biosynthesis. Acta Crystallogr. F Struct. Biol. Commun. 68:824–28
     [Google Scholar]
  73. 73.
    Lallemand LA, Zubieta C, Lee SG, Wang Y, Acajjaoui S et al. 2012. A structural basis for the biosynthesis of the major chlorogenic acids found in coffee. Plant Physiol 160:249–60
     [Google Scholar]
  74. 74.
    Landis JB, Miller CM, Broz AK, Bennett AA, Carrasquilla-Garcia N et al. 2021. Migration through a major Andean ecogeographic disruption as a driver of genetic and phenotypic diversity in a wild tomato species. Mol. Biol. Evol. 38:3202–19
     [Google Scholar]
  75. 75.
    Landmann C, Hucherig S, Fink B, Hoffmann T, Dittlein D et al. 2011. Substrate promiscuity of a rosmarinic acid synthase from lavender (Lavandula angustifolia L.). Planta 234:305–20
     [Google Scholar]
  76. 76.
    Lashbrooke J, Cohen H, Levy-Samocha D, Tzfadia O, Panizel I et al. 2016. MYB107 and MYB9 homologs regulate suberin deposition in angiosperms. Plant Cell 28:2097–116
     [Google Scholar]
  77. 77.
    Lee J-W, Seo H, Young C, Trinh CT 2021. Probing specificities of alcohol acyltransferases for designer ester biosynthesis with a high-throughput microbial screening platform. Biotechnol. Bioeng. 118:4655–67
     [Google Scholar]
  78. 78.
    Leong BJ, Hurney S, Fiesel P, Anthony TM, Moghe G et al. 2022. Identification of BAHD acyltransferases associated with acylinositol biosynthesis in Solanum quitoense (naranjilla). Plant Direct 6:e415
     [Google Scholar]
  79. 79.
    Leong BJ, Hurney SM, Fiesel PD, Moghe GD, Jones AD, Last RL. 2020. Specialized metabolism in a nonmodel nightshade: trichome acylinositol biosynthesis. Plant Physiol 183:915–24
     [Google Scholar]
  80. 80.
    Letunic I, Bork P. 2021. Interactive Tree of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation. Nucleic Acids Res 49:W293–96
     [Google Scholar]
  81. 81.
    Levsh O, Chiang Y-C, Tung CF, Noel JP, Wang Y, Weng J-K. 2016. Dynamic conformational states dictate selectivity toward the native substrate in a substrate-permissive acyltransferase. Biochemistry 55:6314–26
     [Google Scholar]
  82. 82.
    Levsh O, Pluskar T, Carballo V, Mitchell AJ, Weng JK. 2019. Independent evolution of rosmarinic acid biosynthesis in two sister families under the Lamiids clade of flowering plants. J. Biol. Chem. 294:15193–205
     [Google Scholar]
  83. 83.
    Liang H, Lin X, Yang P, Sun Y, Wu Q et al. 2022. Genome-wide identification of BAHD superfamily and functional characterization of bornyl acetyltransferases involved in the bornyl acetate biosynthesis in Wurfbainia villosa. Front. Plant Sci. 13:860152
     [Google Scholar]
  84. 84.
    Lou Y-R, Anthony TM, Fiesel PD, Arking RE, Christensen EM et al. 2021. It happened again: convergent evolution of acylglucose specialized metabolism in black nightshade and wild tomato. Sci. Adv. 7:eabj8726
     [Google Scholar]
  85. 85.
    Luu VT, Weinhold A, Ullah C, Dressel S, Schoettner M et al. 2017. O-Acyl sugars protect a wild tobacco from both native fungal pathogens and a specialist herbivore. Plant Physiol 174:370–86
     [Google Scholar]
  86. 86.
    Ma XY, Koepke J, Panjikar S, Fritzsch G, Stockigt J. 2005. Crystal structure of vinorine synthase, the first representative of the BAHD superfamily. J. Biol. Chem. 280:13576–83
     [Google Scholar]
  87. 87.
    McCormick SP, Hohn TM, Desjardins AE. 1996. Isolation and characterization of Tri3, a gene encoding 15-O-acetyltransferase from Fusarium sporotrichioides. Appl. Environ. Microbiol. 62:353–59
     [Google Scholar]
  88. 88.
    McNevin JP, Woodward W, Hannoufa A, Feldmann KA, Lemieux B. 1993. Isolation and characterization of eceriferum (cer) mutants induced by T-DNA insertions in Arabidopsis thaliana. Genome 36:610–18
     [Google Scholar]
  89. 89.
    Miller HI. 2001. The story of Taxol: nature and politics in the pursuit of an anti-cancer drug. Nat. Med. 7:148
     [Google Scholar]
  90. 90.
    Moghe GD, Leong BJ, Hurney SM, Jones AD, Last RL. 2017. Evolutionary routes to biochemical innovation revealed by integrative analysis of a plant-defense related specialized metabolic pathway. eLife 6:e28468Delineates, using a metabolomics-guided functional evolutionary genomics approach, key events in the diversification of ASAT-based O-acyl sugars in the Solanaceae.
     [Google Scholar]
  91. 91.
    Moglia A, Acquadro A, Eljounaidi K, Milani AM, Cagliero C et al. 2016. Genome-wide identification of BAHD acyltransferases and in vivo characterization of HQT-like enzymes involved in caffeoylquinic acid synthesis in globe artichoke. Front. Plant Sci. 7:1424
     [Google Scholar]
  92. 92.
    Moglia A, Lanteri S, Comino C, Hill L, Knevitt D et al. 2014. Dual catalytic activity of hydroxycinnamoyl-Coenzyme A quinate transferase from tomato allows it to moonlight in the synthesis of both mono- and dicaffeoylquinic acids. Plant Physiol 166:1777–87
     [Google Scholar]
  93. 93.
    Molina I, Kosma D. 2015. Role of HXXXD-motif/BAHD acyltransferases in the biosynthesis of extracellular lipids. Plant Cell Rep 34:587–601
     [Google Scholar]
  94. 94.
    Molina I, Li-Beisson Y, Beisson F, Ohlrogge JB, Pollard M. 2009. Identification of an Arabidopsis feruloyl-coenzyme A transferase required for suberin synthesis. Plant Physiol 151:1317–28
     [Google Scholar]
  95. 95.
    Morales-Quintana L, Moya-León MA, Herrera R. 2015. Computational study enlightens the structural role of the alcohol acyltransferase DFGWG motif. J. Mol. Model. 21:216
     [Google Scholar]
  96. 96.
    Morales-Quintana L, Nuñez-Tobar MX, Moya-León MA, Herrera R. 2013. Molecular dynamics simulation and site-directed mutagenesis of alcohol acyltransferase: a proposed mechanism of catalysis. J. Chem. Inf. Model. 53:2689–700
     [Google Scholar]
  97. 97.
    Mota TR, de Souza WR, Oliveira DM, Martins PK, Sampaio BL et al. 2021. Suppression of a BAHD acyltransferase decreases p-coumaroyl on arabinoxylan and improves biomass digestibility in the model grass Setaria viridis. Plant J 105:136–50
     [Google Scholar]
  98. 98.
    Murayama K, Kato-Murayama M, Sato T, Hosaka T, Ishiguro K et al. 2021. Anthocyanin 5,3′-aromatic acyltransferase from Gentiana triflora, a structural insight into biosynthesis of a blue anthocyanin. Phytochemistry 186:112727Structural analyses of Gt5,3′AT were conducted to identify their underlying mechanism, revealing that acyl group preference for the enzymes was determined by four well-conserved amino acid positions present in both aromatic and aliphatic CoA-binding acyltransferases.
     [Google Scholar]
  99. 99.
    Muroi A, Ishihara A, Tanaka C, Ishizuka A, Takabayashi J et al. 2009. Accumulation of hydroxycinnamic acid amides induced by pathogen infection and identification of agmatine coumaroyltransferase in Arabidopsis thaliana. Planta 230:517–27
     [Google Scholar]
  100. 100.
    Nadakuduti SS, Uebler JB, Liu X, Jones AD, Barry CS. 2017. Characterization of trichome-expressed BAHD acyltransferases in Petunia axillaris reveals distinct acylsugar assembly mechanisms within the Solanaceae. Plant Physiol 175:36–50
     [Google Scholar]
  101. 101.
    Nagasawa N, Bogaki T, Iwamatsu A, Hamachi M, Kumagai C. 1998. Cloning and nucleotide sequence of the alcohol acetyltransferase II gene (ATF2) from Saccharomyces cerevisiae Kyokai No. 7. Biosci. Biotechnol. Biochem. 62:1852–57
     [Google Scholar]
  102. 102.
    Nakayama T, Suzuki H, Nishino T. 2003. Anthocyanin acyltransferases: specificities, mechanism, phylogenetics, and applications. J. Mol. Catal. B Enzym. 23:117–32
     [Google Scholar]
  103. 103.
    Navarro-Retamal C, Gaete-Eastman C, Herrera R, Caballero J, Alzate-Morales JH. 2016. Structural and affinity determinants in the interaction between alcohol acyltransferase from F. x ananassa and several alcohol substrates: a computational study. PLOS ONE 11:e0153057
     [Google Scholar]
  104. 104.
    Nawarathne IN, Walker KD. 2010. Point mutations (Q19P and N23K) increase the operational solubility of a 2α-O-benzoyltransferase that conveys various acyl groups from CoA to a taxane acceptor. J. Nat. Prod. 73:151–59
     [Google Scholar]
  105. 105.
    Negruk V, Yang P, Subramanian M, McNevin JP, Lemieux B. 1996. Molecular cloning and characterization of the CER2 gene of Arabidopsis thaliana. Plant J 9:137–45
     [Google Scholar]
  106. 106.
    Nevarez DM, Mengistu YA, Nawarathne IN, Walker KD. 2009. An N-aroyltransferase of the BAHD superfamily has broad aroyl CoA specificity in vitro with analogues of N-dearoylpaclitaxel. J. Am. Chem. Soc. 131:5994–6002
     [Google Scholar]
  107. 107.
    Niklas KJ, Cobb ED, Matas AJ. 2017. The evolution of hydrophobic cell wall biopolymers: from algae to angiosperms. J. Exp. Bot. 68:5261–69
     [Google Scholar]
  108. 108.
    Ning J, Moghe GD, Leong B, Kim J, Ofner I et al. 2015. A feedback-insensitive isopropylmalate synthase affects acylsugar composition in cultivated and wild tomato. Plant Physiol 169:1821–35
     [Google Scholar]
  109. 109.
    Ondari ME, Walker KD. 2008. The Taxol pathway 10-O-acetyltransferase shows regioselective promiscuity with the oxetane hydroxyl of 4-deacetyltaxanes. J. Am. Chem. Soc. 130:17187–94
     [Google Scholar]
  110. 110.
    Onkokesung N, Gaquerel E, Kotkar H, Kaur H, Baldwin IT, Galis I. 2012. MYB8 controls inducible phenolamide levels by activating three novel hydroxycinnamoyl-Coenzyme A:polyamine transferases in Nicotiana attenuata. Plant Physiol 158:389–407
     [Google Scholar]
  111. 111.
    Panikashvili D, Shi JX, Schreiber L, Aharoni A. 2009. The Arabidopsis DCR encoding a soluble BAHD acyltransferase is required for cutin polyester formation and seed hydration properties. Plant Physiol 151:1773–89
     [Google Scholar]
  112. 112.
    Pascal S, Bernard A, Sorel M, Pervent M, Vile D et al. 2013. The Arabidopsis cer26 mutant, like the cer2 mutant, is specifically affected in the very long chain fatty acid elongation process. Plant J 73:733–46
     [Google Scholar]
  113. 113.
    Peng M, Gao Y, Chen W, Wang W, Shen S et al. 2016. Evolutionarily distinct BAHD N-acyltransferases are responsible for natural variation of aromatic amine conjugates in rice. Plant Cell 28:1533–50
     [Google Scholar]
  114. 114.
    Perrin J, Kulagina N, Unlubayir M, Munsch T, Carqueijeiro I et al. 2021. Exploiting spermidine N-hydroxycinnamoyltransferase diversity and substrate promiscuity to produce various trihydroxycinnamoyl spermidines and analogues in engineered yeast. ACS Synth. Biol. 10:286–96
     [Google Scholar]
  115. 115.
    Petersen M. 2016. Hydroxycinnamoyltransferases in plant metabolism. Phytochem. Rev. 15:699–727
     [Google Scholar]
  116. 116.
    Petersen M, Hans J, Matern U 2010. Biosynthesis of phenylpropanoids and related compounds. Annual Plant Reviews, Volume 40: Biochemistry of Plant Secondary Metabolism M Wink 182–257. Chichester, UK: Wiley-Blackwell. 2nd ed.
     [Google Scholar]
  117. 117.
    Pezeshki S, Petersen M 2018. Rosmarinic acid and related metabolites. Biotechnology of Natural Products W Schwab, BM Lange, M Wüst 25–60. Cham, Switz: Springer
     [Google Scholar]
  118. 118.
    Philippe G, Sørensen I, Jiao C, Sun X, Fei Z et al. 2020. Cutin and suberin: assembly and origins of specialized lipidic cell wall scaffolds. Curr. Opin. Plant Biol. 55:11–20
     [Google Scholar]
  119. 119.
    Pollard M, Beisson F, Li Y, Ohlrogge JB. 2008. Building lipid barriers: biosynthesis of cutin and suberin. Trends Plant Sci 13:236–46
     [Google Scholar]
  120. 120.
    Preuss D, Lemieux B, Yen G, Davis RW 1993. A conditional sterile mutation eliminates surface components from Arabidopsis pollen and disrupts cell signaling during fertilization. Genes Dev 7:974–85
     [Google Scholar]
  121. 121.
    Renault H, Werck-Reichhart D, Weng J-K. 2019. Harnessing lignin evolution for biotechnological applications. Curr. Opin. Biotechnol. 56:105–11
     [Google Scholar]
  122. 122.
    Rinaldo AR, Cavallini E, Jia Y, Moss SMA, McDavid DAJ et al. 2015. A grapevine anthocyanin acyltransferase, transcriptionally regulated by VvMYBA, can produce most acylated anthocyanins present in grape skins. Plant Physiol 169:1897–916
     [Google Scholar]
  123. 123.
    Roumani M, Besseau S, Gagneul D, Robin C, Larbat R 2021. Phenolamides in plants: an update on their function, regulation, and origin of their biosynthetic enzymes. J. Exp. Bot. 72:2334–55
     [Google Scholar]
  124. 124.
    Ru M, Wang KR, Bai ZQ, Peng L, He SX et al. 2017. Molecular cloning and characterisation of two enzymes involved in the rosmarinic acid biosynthesis pathway of Prunella vulgaris L. Plant Cell Tissue Organ Cult 128:381–90
     [Google Scholar]
  125. 125.
    Saigo T, Wang T, Watanabe M, Tohge T. 2020. Diversity of anthocyanin and proanthocyanin biosynthesis in land plants. Curr. Opin. Plant Biol. 55:93–99Provides current knowledge of the diversity of chemical structure and regulators of anthocyanin/proanthocyanidin biosynthesis using cross-species comparisons in order to assess aspects of metabolic evolution pertinent to these pathways.
     [Google Scholar]
  126. 126.
    Sander M. 2010. Molekularbiologische und biochemische Untersuchungen von Hydroxycinnamoyltransferasen aus Coleus blumei und Glechoma hederacea PhD Diss., Philipps Univ. Marburg Marburg, Ger:.
  127. 127.
    Sander M, Petersen M. 2011. Distinct substrate specificities and unusual substrate flexibilities of two hydroxycinnamoyltransferases, rosmarinic acid synthase and hydroxycinnamoyl-CoA:shikimate hydroxycinnamoyl-transferase, from Coleus blumei Benth. Planta 233:1157–71
     [Google Scholar]
  128. 128.
    Scheller HV, Ulvskov P 2010. Hemicelluloses. Annu. Rev. Plant Biol. 61:263–89
     [Google Scholar]
  129. 129.
    Schilmiller AL, Moghe GD, Fan PX, Ghosh B, Ning J et al. 2015. Functionally divergent alleles and duplicated loci encoding an acyltransferase contribute to acylsugar metabolite diversity in Solanum trichomes. Plant Cell 27:1002–17
     [Google Scholar]
  130. 130.
    Schmidt GW, Jirschitzka J, Porta T, Reichelt M, Luck K et al. 2015. The last step in cocaine biosynthesis is catalyzed by a BAHD acyltransferase. Plant Physiol 167:89–101
     [Google Scholar]
  131. 131.
    Schnabel A, Athmer B, Manke K, Schumacher F, Cotinguiba F, Vogt T. 2021. Identification and characterization of piperine synthase from black pepper, Piper nigrum L. Commun. Biol. 4:445
     [Google Scholar]
  132. 132.
    Schoch G, Goepfert S, Morant M, Hehn A, Meyer D et al. 2001. CYP98A3 from Arabidopsis thaliana is a 3′-hydroxylase of phenolic esters, a missing link in the phenylpropanoid pathway. J. Biol. Chem. 276:36566–74
     [Google Scholar]
  133. 133.
    Serra O, Figueras M, Franke R, Prat S, Molinas M. 2010. Unraveling ferulate role in suberin and periderm biology by reverse genetics. Plant Signal. Behav. 5:953–58
     [Google Scholar]
  134. 134.
    Serra O, Hohn C, Franke R, Prat S, Molinas M, Figueras M. 2010. A feruloyl transferase involved in the biosynthesis of suberin and suberin-associated wax is required for maturation and sealing properties of potato periderm. Plant J 62:277–90
     [Google Scholar]
  135. 135.
    Shalit M, Guterman I, Volpin H, Bar E, Tamari T et al. 2003. Volatile ester formation in roses. Identification of an acetyl-coenzyme A. Geraniol/citronellol acetyltransferase in developing rose petals. Plant Physiol 131:1868–76
     [Google Scholar]
  136. 136.
    Sharma PK, Sangwan NS, Bose SK, Sangwan RS. 2013. Biochemical characteristics of a novel vegetative tissue geraniol acetyltransferase from a monoterpene oil grass (Palmarosa, Cymbopogon martinii var. Motia) leaf. Plant Sci. 203:63–73
     [Google Scholar]
  137. 137.
    Sharma S, Ahmed M, Akhter Y 2020. Fungal acetyltransferases structures, mechanisms and inhibitors: a review. Int. J. Biol. Macromol. 157:626–40
     [Google Scholar]
  138. 138.
    Smith RA, Beebe ET, Bingman CA, Vander Meulen K, Eugene A et al. 2022. Identification and characterization of a set of monocot BAHD monolignol transferases. Plant Physiol 189:37–48
     [Google Scholar]
  139. 139.
    Smith RA, Gonzales-Vigil E, Karlen SD, Park J-Y, Lu F et al. 2015. Engineering monolignol p-coumarate conjugates into poplar and Arabidopsis lignins. Plant Physiol 169:2992–3001
     [Google Scholar]
  140. 140.
    Sonnante G, D'Amore R, Blanco E, Pierri CL, De Palma M et al. 2010. Novel hydroxycinnamoyl-Coenzyme A quinate transferase genes from artichoke are involved in the synthesis of chlorogenic acid. Plant Physiol 153:1224–38
     [Google Scholar]
  141. 141.
    Souleyre EJF, Chagné D, Chen X, Tomes S, Turner RM et al. 2014. The AAT1 locus is critical for the biosynthesis of esters contributing to ‘ripe apple’ flavour in ‘Royal Gala’ and ‘Granny Smith’ apples. Plant J 78:903–15
     [Google Scholar]
  142. 142.
    Souleyre EJF, Greenwood DR, Friel EN, Karunairetnam S, Newcomb RD. 2005. An alcohol acyl transferase from apple (cv. Royal Gala), MpAAT1, produces esters involved in apple fruit flavor. FEBS J 272:3132–44
     [Google Scholar]
  143. 143.
    Srinivasan P, Smolke CD. 2019. Engineering a microbial biosynthesis platform for de novo production of tropane alkaloids. Nat. Commun. 10:3634
     [Google Scholar]
  144. 144.
    St.-Pierre B, De Luca V 2000. Evolution of acyltransferase genes: origin and diversification of the BAHD superfamily of acyltransferases involved in secondary metabolism. Recent Adv. Phytochem. 34:285–315
     [Google Scholar]
  145. 145.
    Suthar MK, Purohit PM, Saran PL. 2021. Molecular cloning, expression and in-silico characterization of rosmarinic acid synthase from Ocimum tenuiflorum L. J. Plant Biochem. Biotechnol. 30:317–25
     [Google Scholar]
  146. 146.
    Tewksbury JJ, Nabhan GP. 2001. Directed deterrence by capsaicin in chillies. Nature 412:403–4
     [Google Scholar]
  147. 147.
    Tewksbury JJ, Reagan KM, Machnicki NJ, Carlo TA, Haak DC et al. 2008. Evolutionary ecology of pungency in wild chilies. PNAS 105:11808–11
     [Google Scholar]
  148. 148.
    Tohge T, Wendenburg R, Ishihara H, Nakabayashi R, Watanabe M et al. 2016. Characterization of a recently evolved flavonol-phenylacyltransferase gene provides signatures of natural light selection in Brassicaceae. Nat. Commun. 7:12399
     [Google Scholar]
  149. 149.
    Tohge T, Zhang Y, Peterek S, Matros A, Rallapalli G et al. 2015. Ectopic expression of snapdragon transcription factors facilitates the identification of genes encoding enzymes of anthocyanin decoration in tomato. Plant J 83:686–704
     [Google Scholar]
  150. 150.
    Tokai T, Fujimura M, Inoue H, Aoki T, Ohta K et al. 2005. Concordant evolution of trichothecene 3-O-acetyltransferase and an rDNA species phylogeny of trichothecene-producing and non-producing fusaria and other ascomycetous fungi. Microbiology 151:509–19
     [Google Scholar]
  151. 151.
    Tropper M, Wolf L-S, Lanig H, Kreis W. 2021. In silico, in vitro, and structural investigations on BAHD-enzymes from different species able to malonylate 21-hydroxypregnanes. Planta Med 87:1278
     [Google Scholar]
  152. 152.
    Tuominen LK, Johnson VE, Tsai C-J. 2011. Differential phylogenetic expansions in BAHD acyltransferases across five angiosperm taxa and evidence of divergent expression among Populus paralogues. BMC Genom 12:236
     [Google Scholar]
  153. 153.
    Unno H, Ichimaida F, Suzuki H, Takahashi S, Tanaka Y et al. 2007. Structural and mutational studies of anthocyanin malonyltransferases establish the features of BAHD enzyme catalysis. J. Biol. Chem. 282:15812–22
     [Google Scholar]
  154. 154.
    Vanholme R, De Meester B, Ralph J, Boerjan W 2019. Lignin biosynthesis and its integration into metabolism. Curr. Opin. Biotechnol. 56:230–39
     [Google Scholar]
  155. 155.
    Viskupicova J, Ondrejovic M, Sturdik E. 2009. The potential and practical applications of acylated flavonoids. Pharmazie 64:355–60
     [Google Scholar]
  156. 156.
    Wagner A, Ralph J, Akiyama T, Flint H, Phillips L et al. 2007. Exploring lignification in conifers by silencing hydroxycinnamoyl-CoA:shikimate hydroxycinnamoyltransferase in Pinus radiata. PNAS 104:11856–61
     [Google Scholar]
  157. 157.
    Walker AM, Hayes RP, Youn B, Vermerris W, Sattler SE, Kang CH. 2013. Elucidation of the structure and reaction mechanism of Sorghum hydroxycinnamoyltransferase and its structural relationship to other coenzyme A-dependent transferases and synthases. Plant Physiol 162:640–51
     [Google Scholar]
  158. 158.
    Walker K, Croteau R. 2000. Taxol biosynthesis: molecular cloning of a benzoyl-CoA:taxane 2α-O-benzoyltransferase cDNA from Taxus and functional expression in Escherichia coli. PNAS 97:13591–96
     [Google Scholar]
  159. 159.
    Wang K, Guo Z-L, Zhou W-T, Zhang C, Zhang Z-Y et al. 2018. The regulation of sporopollenin biosynthesis genes for rapid pollen wall formation. Plant Physiol 178:283–94
     [Google Scholar]
  160. 160.
    Wang LL, Chen K, Zhang M, Ye M, Qiao X. 2022. Catalytic function, mechanism, and application of plant acyltransferases. Crit. Rev. Biotechnol. 42:125–44
     [Google Scholar]
  161. 161.
    Wang PP, Liu H, Gao S, Cheng AX. 2017. Functional characterization of a hydroxyacid/alcohol hydroxycinnamoyl transferase produced by the liverwort Marchantia emarginata. Molecules 22:1854
     [Google Scholar]
  162. 162.
    Weinhold A, Baldwin IT. 2011. Trichome-derived O-acyl sugars are a first meal for caterpillars that tags them for predation. PNAS 108:7855–59This study on O-acylsugar multitrophic roles illustrates the importance of natural history-guided research for exploring ecological sophistication in the mode of action of BAHD-dependent metabolites.
     [Google Scholar]
  163. 163.
    Wilkerson CG, Mansfield SD, Lu F, Withers S, Park J-Y et al. 2014. Monolignol ferulate transferase introduces chemically labile linkages into the lignin backbone. Science 344:90–93A BAHD feruloyl-CoA monolignol transferase from Angelica sinensis was overexpressed in poplar to introduce ester labile linkages in the lignin polymers, increasing saccharification yield and demonstrating the possibility to modify lignin composition through biotechnological approaches.
     [Google Scholar]
  164. 164.
    Williams LK, Zhang X, Caner S, Tysoe C, Nguyen NT et al. 2015. The amylase inhibitor montbretin A reveals a new glycosidase inhibition motif. Nat. Chem. Biol. 11:691–96
     [Google Scholar]
  165. 165.
    Wong DCJ, Perkins J, Peakall R. 2022. Anthocyanin and flavonol glycoside metabolic pathways underpin floral color mimicry and contrast in a sexually deceptive orchid. Front. Plant Sci. 13:860997
     [Google Scholar]
  166. 166.
    Xia J, Guo Z, Yang Z, Han H, Wang S et al. 2021. Whitefly hijacks a plant detoxification gene that neutralizes plant toxins. Cell 184:1693–705.e17Expands our understanding of plant BAHDs to the postingestive side of plant-insect interactions by describing the horizontal gene transfer of a plant-derived BAHD by whiteflies as a key determinant to plant toxin inactivation.
     [Google Scholar]
  167. 167.
    Xin Z-J, Li X-W, Bian L, Sun X-L. 2017. Tea green leafhopper, Empoasca vitis, chooses suitable host plants by detecting the emission level of (3Z)-hexenyl acetate. Bull. Entomol. Res. 107:77–84
     [Google Scholar]
  168. 168.
    Xu D, Shi J, Rautengarten C, Yang L, Qian X et al. 2017. Defective pollen wall 2 (DPW2) encodes an acyl transferase required for rice pollen development. Plant Physiol 173:240–55
     [Google Scholar]
  169. 169.
    Xu Y, Geng L, Zhang Y, Jones JA, Zhang M et al. 2022. De novo biosynthesis of salvianolic acid B in Saccharomyces cerevisiae engineered with the rosmarinic acid biosynthetic pathway. J. Agric. Food Chem. 70:2290–302
     [Google Scholar]
  170. 170.
    Yamane M, Takenoya M, Yajima S, Sue M 2020. Crystal structure of barley agmatine coumaroyltransferase, an N-acyltransferase from the BAHD superfamily. Acta Crystallogr. F Struct. Biol. Commun. 76:590–96
     [Google Scholar]
  171. 171.
    Yamane M, Takenoya M, Yajima S, Sue M. 2021. Molecular and structural characterization of agmatine coumaroyltransferase in Triticeae, the key regulator of hydroxycinnamic acid amide accumulation. Phytochemistry 189:112825
     [Google Scholar]
  172. 172.
    Yang Q, Reinhard K, Schiltz E, Matern U. 1997. Characterization and heterologous expression of hydroxycinnamoyl/benzoyl-CoA:anthranilate N-hydroxycinnamoyl/benzoyltransferase from elicited cell cultures of carnation, Dianthus caryophyllus L. Plant Mol. Biol. 35:777–89
     [Google Scholar]
  173. 173.
    Yauk Y-K, Souleyre EJF, Matich AJ, Chen X, Wang MY et al. 2017. Alcohol acyl transferase 1 links two distinct volatile pathways that produce esters and phenylpropenes in apple fruit. Plant J 91:292–305
     [Google Scholar]
  174. 174.
    Yuan YW, Rebocho AB, Sagawa JM, Stanley LE, Bradshaw HD Jr. 2016. Competition between anthocyanin and flavonol biosynthesis produces spatial pattern variation of floral pigments between Mimulus species. PNAS 113:2448–53
     [Google Scholar]
  175. 175.
    Zhang C. 2018. Genetic and genomic analysis of BAHD acyltransferases that decorate cell wall components with phenolic esters and alter plant biomass recalcitrance PhD Diss., Univ. Okla. Norman, OK:
  176. 176.
    Zhou W, Kong W, Yang C, Feng R, Xi W. 2021. Alcohol acyltransferase is involved in the biosynthesis of C6 esters in apricot (Prunus armeniaca L.) fruit. Front. Plant Sci. 12:763139
     [Google Scholar]
  177. 177.
    Zhu Y, Rudell DR, Mattheis JP. 2008. Characterization of cultivar differences in alcohol acyltransferase and 1-aminocyclopropane-1-carboxylate synthase gene expression and volatile ester emission during apple fruit maturation and ripening. Postharvest Biol. Technol. 49:330–39
     [Google Scholar]
/content/journals/10.1146/annurev-arplant-062922-050122
Loading
BAHD Company: The Ever-Expanding Roles of the BAHD Acyltransferase Gene Family in Plants
Annual Review of Plant Biology 74, 165 (2023); https://doi.org/10.1146/annurev-arplant-062922-050122
/content/journals/10.1146/annurev-arplant-062922-050122
/content/journals/10.1146/annurev-arplant-062922-050122
Loading

Data & Media loading...

Supplemental Material

Supplementary Data

  • Article Type: Review Article

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error