Mechanism of Auxin-Regulated Gene Expression in Plants

Plant hormones control most aspects of the plant life cycle by regulating genome expression. Expression of auxin-responsive genes involves interactions among auxin-responsive DNA sequence elements, transcription factors and trans-acting transcriptional repressors. Transcriptional output from these auxin signaling complexes is regulated by proteasome-mediated degradation that is triggered by interaction with auxin receptor-E3 ubiquitin ligases such SCF^TIR1. Auxin signaling components are conserved throughout land plant evolution and have proliferated and specialized to control specific developmental processes.