1932

Abstract

Short segments of identity by descent (IBD) between individuals with no known relationship can be detected using genome-wide single nucleotide polymorphism data and recently developed statistical methodology. Emerging applications for the detected IBD segments include IBD mapping, haplotype phase inference, genotype imputation, and inference of population structure. In this review, we explain the principles behind methods for IBD segment detection, describe recently developed methods, discuss approaches to comparing methods, and give an overview of applications.

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/content/journals/10.1146/annurev-genet-110711-155534
2012-12-15
2024-06-14
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  • Article Type: Review Article
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