Basal Ganglia Circuits for Reward Value–Guided Behavior

Supplementary Data

• Supplemental Figure 1. Object skill expressed as automatic gaze bias. (a) Procedure for learning stable values of visual objects. Half of the objects were associated with a reward (high-valued objects) and the other associated with no (or a small) reward (low-valued objects). (b) Free viewing procedure for testing the value-based gaze bias. On each trial, 4 fractal objects were chosen pseudo-randomly from a set of 8 learned objects (a), were presented simultaneously, and the monkey freely looked at them, but no reward was delivered. Yellow lines indicate saccade trajectories. The monkey tended to look at high-valued objects (denoted as 'H'). (c, d) The percentage of the gaze duration on each object before (d) and after (c) the long-term learning. Red and blue indicate high- and low-valued objects respectively.

  

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  Supplemental Figure 2. Changes in the neuronal and behavioral responses during the combination of short-term and long-term learning of object values. The monkey performed the object value learning task in two stages of long-term learning: initial stage where novel objects were used as the saccade target (a, Day 1), and late stage where objects had been learned more than 4 times (b, Day > 4). Compared for each stage are: CDt neuronal discrimination, CDh neuronal discrimination, and behavioral discrimination based on the target acquisition time. Each graph shows the across-trial changes in the neuronal or behavioral discrimination within a learning session, computed as an ROC area. The statistical significance of the discrimination was tested for the early and late trials during the learning in two ways: 1) comparison with the neutral value (ROC 0.5), and 2) comparison between the early and late trials. * p<0.05, ** p<0.01, *** p<0.001, n.s. non-significant.

  

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  Download Supplemental Figures 1 and 2 as a single PDF.