1932

Abstract

Writing this biography forced me to look back over my career as a scientist, teacher, wife, and mother. To my surprise, a lifelong theme emerged that I was unaware of, that is, the role of maintaining balance between work and family, science and teaching, mentorship and administration, and personal values and challenges. My primary mentor, Dr. Doris Calloway, demonstrated the importance of maintaining balance. My interest in nutrition started as a preschooler living on a farm where I learned firsthand the importance of balancing the expense of providing good nutrition to the livestock with potential income. In our small high school, I became acquainted with the fascinating field of chemistry, but found it critical to balance that interest with a politically correct field of study for a woman in the early 1960s. I chose dietetics for its strong roots in chemistry. As a US Army dietitian, I learned firsthand how to conduct metabolic studies and knew, immediately, that I had to balance that interest with future opportunities feasible for a dietitian. I chose the University of California, Berkeley, for my PhD because it needed to train dietitians in research to balance an emerging need to offer undergraduates a practicum in dietetics. My subsequent faculty appointment there enabled me to develop novel isotopic approaches for studying zinc and prenatal nutrition, and balance my research with teaching and administrative responsibilities. During the next 40 years, my work as a Berkeley professor led to appointments at the Western Human Nutrition Research Center and Children's Hospital Oakland Research Institute, while balancing my responsibilities as a wife and a mother to my two sons. Balance is defined as a condition in which different elements are equal or in the correct proportions. It is extremely satisfying to look back and see evidence of successfully balancing the disparate elements of my career.

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2019-08-21
2024-12-04
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Literature Cited

  1. 1.
    Baer MT, King JC. 1984. Tissue zinc levels and zinc excretion during experimental zinc depletion in young men. Am. J. Clin. Nutr. 39:556–70
    [Google Scholar]
  2. 2.
    Baer MT, King JC, Tamura T, Margen S 1978. Acne in zinc deficiency. Arch. Dermatol. 114:1093
    [Google Scholar]
  3. 3.
    Baer MT, King JC, Tamura T, Margen S, Bradfield RB et al. 1985. Nitrogen utilization, enzyme activity, glucose intolerance and leukocyte chemotaxis in human experimental zinc depletion. Am. J. Clin. Nutr. 41:1220–35
    [Google Scholar]
  4. 4.
    Bezerra F, Laboissiere F, King JC, Donangelo C 2002. Pregnancy and lactation affect markers of calcium and bone metabolism differently in adolescent and adult women with low calcium intakes. J. Nutr. 132:2183–87
    [Google Scholar]
  5. 5.
    Bronstein MN, Mak RP, King JC 1996. Unexpected relationship between fat mass and basal metabolic rate in pregnant women. Br. J. Nutr. 75:659–68
    [Google Scholar]
  6. 6.
    Caan B, Horgen DM, Margen S, King JC, Jewell NP 1987. Benefits associated with WIC supplemental feeding during the interpregnancy interval. Am. J. Clin. Nutr. 45:29–41
    [Google Scholar]
  7. 7.
    Cvijanovich NZ, King JC, Flori HR, Gildengorin G, Vinks AA, Wong HR 2016. Safety and dose escalation study of intravenous zinc supplementation in pediatric critical illness. J. Parenter. Enter. Nutr. 40:860–68
    [Google Scholar]
  8. 8.
    Golden MHN. 1989. The diagnosis of zinc deficiency. Zinc in Human Biology CF Mills 323–33 London: Springer-Verlag
    [Google Scholar]
  9. 9.
    Hall AG, Ngu T, Nga HT, Quyen PN, Hong Anh PT, King JC 2017. An animal-source food supplement increases micronutrient intakes and iron status among reproductive-age women in rural Vietnam. J. Nutr. 147:1200–8
    [Google Scholar]
  10. 10.
    Hambidge KM, King JC, Kern DL, English-Westcott JL, Stall C 1990. Pre-breakfast plasma zinc concentrations: the effect of previous meals. J. Trace Elem. Electrolytes Health Dis. 4:229–31
    [Google Scholar]
  11. 11.
    Hambidge KM, Krebs NF, Miller L 1998. Evaluation of zinc metabolism with use of stable-isotope techniques: implications for the assessment of zinc status. Am. J. Clin. Nutr. 68:Suppl.410S–13S
    [Google Scholar]
  12. 12.
    Holland TC, Killilea DW, Shenvi SV, King JC 2015. Acute changes in cellular zinc alters zinc uptake rates prior to zinc transporter gene expression in Jurkat cells. BioMetals 28:987–96
    [Google Scholar]
  13. 13.
    Kim J, Paik HY, Joung H, Woodhouse LR, Li S, King JC 2004. Zinc supplementation reduces fractional zinc absorption in young and elderly Korean women. J. Am. Coll. Nutr. 23:309–15
    [Google Scholar]
  14. 14.
    Kim J, Paik HY, Joung H, Woodhouse LR, Li S, King JC 2007. Effect of dietary phytate on zinc homeostasis in young and elderly Korean women. J. Am. Coll. Nutr. 26:1–9
    [Google Scholar]
  15. 15.
    King CJ. 2014. Change and Governance at the University of California: Comparative Case Studies Berkeley, CA: Cent. Stud. High. Educ.
    [Google Scholar]
  16. 16.
    King JC. 2018. Yet again, serum zinc concentrations are unrelated to zinc intakes. J. Nutr. 148:1399–401
    [Google Scholar]
  17. 17.
    King JC, Calloway DH, Margen S 1973. Nitrogen retention, total body 40K and weight gain in teenage pregnant girls. J. Nutr. 103:772–85
    [Google Scholar]
  18. 18.
    King JC, Cohenour S, Calloway D, Jacobson M 1972. Assessment of nutritional status of teenage pregnant girls. I. Nutrient intake and pregnancy. Am. J. Clin. Nutr. 25:916–25
    [Google Scholar]
  19. 19.
    King JC, Hambidge KM, Westcott JL, Kern DL, Marshall G 1994. Daily variation in plasma zinc concentrations in women fed meals at six-hour intervals. J. Nutr. 124:508–516
    [Google Scholar]
  20. 20.
    King JC, Raynolds WL, Margen S 1978. Absorption of stable isotopes of iron, copper and zinc during oral contraceptive use. Am. J. Clin. Nutr. 31:1198–203
    [Google Scholar]
  21. 21.
    King JC, Shames DM, Lowe NM, Woodhouse LR, Sutherland B et al. 2001. Effect of acute zinc depletion on zinc homeostasis and plasma zinc kinetics in men. Am. J. Clin. Nutr. 74:116–24
    [Google Scholar]
  22. 22.
    Kopp-Hoolihan LE, Van Loan MD, Wong WW, King JC 1999. Fat mass deposition during pregnancy using a four-component model. J. Appl. Physiol. 87:196–202
    [Google Scholar]
  23. 23.
    Kopp-Hoolihan LE, Van Loan MD, Wong WW, King JC 1999. Longitudinal assessment of energy balance in well-nourished, pregnant women. Am. J. Clin. Nutr. 69:697–704
    [Google Scholar]
  24. 24.
    Kurpad A. 2013. Overview of changing protein and amino acid requirements and application to pregnancy requirements. Food Nutr. Bull. 34:234–36
    [Google Scholar]
  25. 25.
    Lowe NM, Shames DM, Woodhouse LR, Matel JS, Roehl R et al. 1997. A compartmental model of zinc metabolism in healthy women using oral and intravenous stable isotope tracers. Am. J. Clin. Nutr. 65:1810–19
    [Google Scholar]
  26. 26.
    Nagy LE, King JC. 1983. Energy expenditure of pregnant women at rest or walking self-paced. Am. J. Clin. Nutr. 38:369–76
    [Google Scholar]
  27. 27.
    Ogra S, Feldman JG, Lippes J 1971. Use-effectiveness of oral contraceptives by demographic characteristics. Fertil. Steril. 22:677–82
    [Google Scholar]
  28. 28.
    Pinna K, Woodhouse LR, Sutherland B, Shames DM, King JC 2001. Exchangeable zinc pool masses and turnover are maintained in healthy men on low zinc intakes. J. Nutr. 131:2288–94
    [Google Scholar]
  29. 29.
    Prasad AS. 1984. Discovery and importance of zinc in human nutrition. Fed. Proc. 43:2829–34
    [Google Scholar]
  30. 30.
    Shames DM, Woodhouse LR, Lowe NM, King JC 2001. Accuracy of simple techniques for estimating fractional zinc absorption in humans. J. Nutr. 131:1854–61
    [Google Scholar]
  31. 31.
    Sian L, Mingyan X, Miller LV, Tong L, Krebs NF, Hambidge KM 1996. Zinc absorption and intestinal losses of endogenous zinc in young Chinese women with marginal zinc intakes. Am. J. Clin. Nutr. 63:348–53
    [Google Scholar]
  32. 32.
    Sparacino G, Shames DM, Vicini P, King JC, Cobelli C 2002. Double isotope tracer method for measuring fractional zinc absorption: theoretical analysis. Am. J. Physiol. Endocrinol. Metab. 282:E679–87
    [Google Scholar]
  33. 33.
    Stein Z, Susser M. 1975. The Dutch famine, 1944–1945, and the reproductive process. I. Effects on six indices at birth. Pediatr. Res. 9:70–76
    [Google Scholar]
  34. 34.
    Swanson CA, King JC. 1982. Zinc utilization in pregnant and nonpregnant women fed controlled diets providing the zinc RDA. J. Nutr. 112:697–707
    [Google Scholar]
  35. 35.
    Swanson CA, King JC. 1983. Reduced serum zinc concentration during pregnancy. Obstet. Gynecol. 62:313–18
    [Google Scholar]
  36. 36.
    Swanson CA, King JC. 1987. Zinc and pregnancy outcome. Am. J. Clin. Nutr. 46:763–71
    [Google Scholar]
  37. 37.
    Swanson CA, Turnlund JR, King JC 1983. Effect of dietary zinc sources and pregnancy on zinc utilization in adult women fed controlled diets. J. Nutr. 113:2557–67
    [Google Scholar]
  38. 38.
    Tu N, King JC, Dirren H, Thu HN, Ngoc QP, Diep AN 2014. Effect of animal-source food supplement prior to and during pregnancy on birthweight and prematurity in rural Vietnam: a brief study description. Food Nutr. Bull. 35:Suppl.S205–8
    [Google Scholar]
  39. 39.
    Vargas Zapata CL, Donangelo CM, Woodhouse LR, Abrams SA, Spencer EM, King JC 2004. Calcium homeostasis during pregnancy and lactation in Brazilian women with low calcium intakes: a longitudinal study. Am. J. Clin. Nutr. 80:417–22
    [Google Scholar]
  40. 40.
    Vesco KK, Karanja N, King JC, Gillman MW, Leo MC et al. 2014. Efficacy of a group-based dietary intervention for limiting gestational weight gain among obese women: a randomized trial. Obesity 22:1989–96
    [Google Scholar]
  41. 41.
    Vesco KK, Leo MC, Karanja N, Gillman MW, McEvoy CT et al. 2016. One-year postpartum outcomes following a weight management intervention in pregnant women with obesity. Obesity 24:2042–49
    [Google Scholar]
  42. 42.
    Wada L, Turnlund JR, King JC 1985. Zinc utilization in young men fed adequate and low zinc intakes. J. Nutr. 115:1345–54
    [Google Scholar]
  43. 43.
    Wallock LM, King JC, Hambidge KM, English-Westcott JE, Pritts J 1993. Meal-induced changes in plasma, erythrocyte, and urinary zinc concentrations in adult women. Am. J. Clin. Nutr. 58:695–701
    [Google Scholar]
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