1932

Abstract

Transcription activator-like (TAL) effectors are encoded by plant-pathogenic bacteria and induce expression of plant host genes. TAL effectors bind DNA on the basis of a unique code that specifies binding of amino acid residues in repeat units to particular DNA bases in a one-to-one correspondence. This code can be used to predict binding sites of natural TAL effectors and to design novel synthetic DNA-binding domains for targeted genome manipulation. Natural mechanisms of resistance in plants against TAL effector–containing pathogens have given insights into new strategies for disease control.

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/content/journals/10.1146/annurev-phyto-082712-102255
2013-08-04
2024-04-23
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  • Article Type: Review Article
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