1932

Abstract

Compounds derived from the isoprenoid/cholesterol biosynthetic pathway have recently been shown to have novel biological activities. These compounds include certain sterols, oxysterols, farnesol, and geranylgeraniol, as well as the diphosphate derivatives of isopentenyl, geranyl, farnesyl, geranylgeranyl, and presqualene. They regulate transcriptional and post-transcriptional events that in turn affect lipid synthesis, meiosis, apoptosis, developmental patterning, protein cleavage, and protein degradation.

Loading

Article metrics loading...

/content/journals/10.1146/annurev.biochem.68.1.157
1999-07-01
2024-04-18
Loading full text...

Full text loading...

/content/journals/10.1146/annurev.biochem.68.1.157
Loading
/content/journals/10.1146/annurev.biochem.68.1.157
Loading

Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error