1932

Abstract

Richard Skalak (1923–1997) played a leadership role in the formative decades of the discipline of biomedical engineering through his technical contributions in biomechanics, his educational influence on students, and his service to many developing societies and journals. But always, the distinguishing marks of his involvement with any activity or person were his generosity, respect and tolerance for others, integrity, and curiosity. These very qualities are what first brought him as a traditional engineer trained in engineering mechanics into the young field of biomedical engineering in the 1960s, and they are what led him to new approaches to cellular and molecular engineering, tissue engineering, and orthopedic biomechanics. His technical papers and lectures on blood cell mechanics, pulmonary circulation, dental implants, and tissue growth were models of clarity and often pointed the way to new areas of exploration, while his personal writings offer advice on life, academic organizations, and the pursuit of significant work. He would be deeply appreciative that this first volume of the is dedicated to his memory.

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1999-08-01
2024-12-13
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Literature Cited

  1. Adell R, Skalak R, Brånemark P-I 1970. A preliminary study of rheology of granulocytes Blut 21:91–105 [Google Scholar]
  2. Bagge U, Skalak R, Attefors R 1977. Granulocyte rheology Adv. Microcirc. 7:29–48 [Google Scholar]
  3. Brånemark P-I, Breine U, Langer L, Skalak R. 1972. Microvascular behavior of platelets in man. In Thrombosis: Risk Factors and Diagnostic Approaches, ed. KM Brinkhous, pp. 183–95. Stuttgart/New York: Schattauer Verlag
  4. Brånemark R, Ohrnell LO, Skalak R, Carlsson L, Brånemark P-I 1998. Biomechanical characterization of osseointegration: an experimental in vivo investigation in the beagle dog J. Orthop. Res. 1661–69 [Google Scholar]
  5. Chien S, Usami S, Skalak R. 1984. Blood flow in small tubes. In Handbook of Physiology–The Cardiovascular System, Section 2, Vol. IV, Microcirculation, Part 1, ed. EM Renkin, CC Michel, pp. 217–49. Bethesda, MD: Am. Physiol. Soc
  6. Dong C, Skalak R, Sung K-LP, Schmid-Schönbein GW, Chien S 1988. Passive deformation analysis of human leukocytes J. Biomech. Eng. 110:27–36 [Google Scholar]
  7. Evans EA, Skalak R. 1979. Mechanics and thermodynamics of biomembranes, Parts 1, 2. CRC Crit. Rev. Bioeng. 3(3):181–418
  8. Fox CF, Skalak R, eds. 1988. Tissue Engineering. New York: Liss. 343 pp
  9. Fung YC. 1981. Biomechanics. Mechanical Properties of Living Tissues. New York/Berlin: Springer-Verlag. 433 pp
  10. Galbraith CG, Skalak R, Chien S 1998. Shear stress induces spatial reorganization of the endothelial cell cytoskeleton Cell Motil. Cytoskelet. 40:317–30 [Google Scholar]
  11. Hansen JC, Skalak R, Chien S, Hoger A 1996. An elastic network model based on the structure of the red blood cell membrane skeleton Biophys. J. 70:146–66 [Google Scholar]
  12. Hansen JC, Skalak R, Chien S, Hoger A 1997. Spectrin properties and the elasticity of the red blood cell membrane skeleton Biorheology 34:327–48 [Google Scholar]
  13. Helmke BP, Bremner SN, Zweifach BW, Skalak R, Schmid-Schönbein GW. 1997. Mechanisms for increased blood flow resistance due to leukocytes. Am. J. Physiol. 273:H2884–90
  14. Netti PA, Baxter LT, Boucher Y, Skalak R, Jain RK 1995. Time-dependent behavior of interstitial fluid pressure in solid tumors: implications for drug delivery Cancer Res. 555451–58 [Google Scholar]
  15. Rydevik B, Lundborg G, Skalak R. 1986. Biomechanics of nerves and nerve injuries. In Basic Biomechanics of the Musculoskeletal System, ed. VH Frankel, M Nordin. Malvern, PA: Lea & Febiger
  16. Schmid-Schönbein GW, Sung K-LP, Tözeren H, Skalak R, Chien S 1981. Passive mechanical properties of human leukocytes Biophys. J. 36:243–56 [Google Scholar]
  17. Secomb TW, Fischer T, Skalak R 1983. The motion of close-packed red blood cells in shear flow Biorheology 20:283–94 [Google Scholar]
  18. Secomb TW, Skalak R 1982. A two-dimensional model for capillary flow of an asymmetric cell Microvasc. Res. 24:194–203 [Google Scholar]
  19. Skalak R 1970. Extensions of extremum principles for slow viscous flows J. Fluid Mech. 42:527–48 [Google Scholar]
  20. Skalak R. 1972. Mechanics of the microcirculation. In Biomechanics. Its Foundations and Objectives, ed. YC Fung, N Perrone, M Anliker, pp. 457–500. Englewood Cliffs, NJ: PrenticeHall
  21. Skalak R. 1977. Current trends in biomechanics. Proc. 15th Ann. Midwest. Mech. Conf., Keynote Lect., pp. 15–26. Chicago: Univ. Ill. Press
  22. Skalak R. 1977. Biomechanics: applications of engineering mechanics. Proc. Eng. Div. Spec. Conf. Mech. Eng.,1st, pp. 53–82. Waterloo, Ontario: Univ. Waterloo Press
  23. Skalak R 1983. Biomechanical considerations in osseointegrated prostheses J. Prosthet. Dent. 49:843–48 [Google Scholar]
  24. Skalak R 1984. Biomechanics at the cellular level: the ALZA Distinguished Lecture Ann. Biomed. Eng. 12305–18 [Google Scholar]
  25. Skalak R 1990. Capillary flow: past, present, and future. Poiseuille Medal Lecture Biorheology 27277–93 [Google Scholar]
  26. Skalak R. 1991. Biomechanics of living organisms. In Encyclopedia of Applied Physics, ed. EH Immergut, 2:489–511. New York: VCH Publ
  27. Skalak R. 1992. Cellular biomechanics. In Encyclopedia of Applied Physics, ed. EH Immergut, 3:141–66. New York: VCH Publ
  28. Skalak R, Brånemark P-I 1969. Deformation of red blood cells in capillaries Science 164:717–19 [Google Scholar]
  29. Skalak R, Chen PH, Chien S 1972. Effect of hematocrit and rouleaux on apparent viscosity in capillaries Biorheology 9:67–82 [Google Scholar]
  30. Skalak R, Chien S, eds. 1987. Handbook of Bioengineering. New York: McGraw- Hill
  31. Skalak R, Dasgupta G, Moss ML, Otten E, Dullemeijer P, Vilmann H 1982. Analytical description of growth J. Theor. Biol. 94:555–77 [Google Scholar]
  32. Skalak R, Dong C, Zhu C 1990. Passive deformations and active motions of leukocytes J. Biomech. Eng. 112:295–302 [Google Scholar]
  33. Skalak R, Özkaya N, Skalak TC 1989. Biofluid mechanics Annu. Rev. Fluid Mech. 21:167–204 [Google Scholar]
  34. Skalak R, Stathis T. 1966. A porous tapered elastic tube model of a vascular bed. In Symposium on Biomechanics, pp. 68–81. New York: ASME
  35. Skalak R, Tözeren H. 1979. Flow mechanics in the microcirculation. In Mathematics of Microcirculation Phenomena, ed. JF Gross, AS Popel, pp. 17–40. New York: Raven
  36. Skalak R, Tözeren A, Zarda PR, Chien S 1973. Strain energy function of red blood cell membranes Biophys. J. 13:245–64 [Google Scholar]
  37. Skierczynski BA, Wilson RJ, Kristan WB Jr, Skalak R 1996. A model of the hydrostatic skeleton of the leech J. Theor. Biol. 181:329–42 [Google Scholar]
  38. Sugihara-Seki M, Skalak R 1997. Asymmetric flows of spherical particles in a cylindrical tube Biorheology 34:155–69 [Google Scholar]
  39. Tözeren H, Skalak R. 1977. A model for leukocyte flow in capillaries. Proc. 1977 Biomech. Symp., 23:39–42. New York: ASME
  40. Wang H, Skalak R 1969. Viscous flow in a cylindrical tube containing a line of spherical particles J. Fluid Mech. 38:75–96 [Google Scholar]
  41. Wiener F, Morkin E, Skalak R, Fishman AP 1966. Wave propagation in the pulmonary circulation Circ. Res. 29:834–50 [Google Scholar]
  42. Zarda PR, Chien S, Skalak R 1977. Elastic deformations of red blood cells J. Biomech. 10:211–21 [Google Scholar]
  43. Zhu C, Skalak R, Schmid-Schönbein GW 1989. One-dimensional steady continuum model of retraction of pseudopod in leukocytes J. Biomech. Eng. 111:69–77 [Google Scholar]
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