1932

Abstract

Three of the most important questions concerning actin function are: () How does actin structure relate to actin function? () How does each of the numerous proteins that interact with actin contribute to actin cytoskeleton function in vivo? () How are the activities of these proteins regulated? Powerful molecular genetics combined with well-established biochemical techniques make the yeast an ideal organism for studies aimed at answering these questions.

The protein sequences and biochemical properties of actin and its interacting proteins and the pathways that regulate these interactions all appear to be conserved, indicating that principles elucidated from studies in yeast will apply to all eukaryotes. In this review, we highlight advances in our general understanding of actin properties, interactions with other proteins, and regulation of the actin cytoskeleton, derived from studies in the budding yeast .

Loading

Article metrics loading...

/content/journals/10.1146/annurev.cellbio.12.1.129
1996-11-01
2024-06-13
Loading full text...

Full text loading...

/content/journals/10.1146/annurev.cellbio.12.1.129
Loading
/content/journals/10.1146/annurev.cellbio.12.1.129
Loading

Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error