1932

Abstract

The SNARE superfamily has become, since its discovery approximately a decade ago, the most intensively studied element of the protein machinery involved in intracellular trafficking. Intracellular membrane fusion in eukaryotes requires SNARE (soluble -ethylmaleimide-sensitive-factor attachment protein receptor) proteins that form complexes bridging the two membranes. Although common themes have emerged from structural and functional studies of SNAREs and other components of the eukaryotic membrane fusion machinery, there is still much to learn about how the assembly and activity of this machinery is choreographed in living cells.

Loading

Article metrics loading...

/content/journals/10.1146/annurev.cellbio.19.110701.155609
2003-11-01
2024-04-14
Loading full text...

Full text loading...

/content/journals/10.1146/annurev.cellbio.19.110701.155609
Loading
/content/journals/10.1146/annurev.cellbio.19.110701.155609
Loading

Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error