1932

Abstract

Although the loss of good health is inherently unpredictable, human behavior at the individual and societal levels profoundly influences the incidence and evolution of disease. In this review, we define the human epidemiological environment and describe key biophysical, economic, sociocultural, and political factors that shape it. The potential impact upon the epidemiological environment of biophysical aspects of global change—changes in the size, mobility, and geographic distribution of the human population; land conversion; agricultural intensification; and climate change—is then examined. Human vulnerability to disease is strongly and deleteriously influenced by many of these ongoing, intensifying alterations. We then examine threats to human defenses against disease, including immune suppression, loss of biodiversity and indigenous knowledge, and the evolution of antibiotic resistance. Effective responses will require greatly enhanced attention by and collaboration among experts in diverse academic disciplines, in the private sector, and in government worldwide.

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1996-11-01
2024-06-14
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Literature Cited

  1. Ehrlich PR, Ehrlich AH. 1970. Population, Resources, Environment: Issues in Human Ecology. San Francisco: Freeman [Google Scholar]
  2. Leaf A. 1989. Potential health effects of global climatic and environmental changes.. New Engl. J. Med. 321:1577–83 [Google Scholar]
  3. Fisher JA. 1994. The Plague Makers. New York: Simon Schuster [Google Scholar]
  4. Pearce F. 1995. Global alert over malaria.. New Sci., May 4–5 [Google Scholar]
  5. Bloom BR, Murray CL. 1992. Tuberculosis: Commentary on a reemergent killer.. Science 257:1055–64 [Google Scholar]
  6. Brown P. 1992. The return of the big killer.. New Sci., Oct 30–37 [Google Scholar]
  7. Glass RI, Libel M, Branding-Bennett AD. 1992. Epidemic cholera in the Americas.. Science 256:1524–25 [Google Scholar]
  8. Nowak R. 1994. Flesh-eating bacteria: not new, but still worrisome.. Science 264:1665 [Google Scholar]
  9. MacKenzie D. 1995. Can we afford not to track deadly viruses?. New Sci., May 4 [Google Scholar]
  10. Morell V. 1995. Chimpanzee outbreak heats up search for Ebola origin.. Science 268:974–75 [Google Scholar]
  11. Altman LK. 1995a. No one can say why virus striking Zaire is so deadly.. New York Times, 13 May 1
  12. Garrett L. 1994. The Coming Plague: Newly Emerging Diseases in a World Out of Balance. New York: Farrar Straus Giroux [Google Scholar]
  13. Nussenzweig RS, Long CA. 1994. Malaria vaccines: multiple targets.. Science 265:1381–83 [Google Scholar]
  14. Ehrlich PR, Holdren JP. 1971. Impact of population growth.. Science 171:1212–17 [Google Scholar]
  15. Holdren JP, Ehrlich PR. 1974. Human population and the global environment.. Am. Sci. 62:282–92 [Google Scholar]
  16. Ehrlich PR, Ehrlich AH. 1990. The Population Explosion. New York: Simon Schuster [Google Scholar]
  17. MacDonald G. 1952. The analysis of equilibrium in malaria.. Trop. Dis. Bull. 47:907–15 [Google Scholar]
  18. Anderson RM, May RM. et al. 1991. The spread of HIV-1 in Africa: sexual contact patterns and the predicted demographic impact of AIDS.. Nature 352:581–87 [Google Scholar]
  19. Cohen MN. 1989. Health and the Rise of Civilization. New Haven, CT: Yale Univ. Press [Google Scholar]
  20. Inhorn MC, Brown PJ. 1990. The anthropology of infectious disease.. Annu. Rev. Anthr. 19:89–117 [Google Scholar]
  21. Fenner F, McAuslan BR, Mims CA, Sambrook J, White DO. 1974. The Biology of Animal Viruses. New York: Academic [Google Scholar]
  22. Bartlett MS. 1957. Measles periodicity and community size.. J. Roy. Stat. Soc. A120:48–70 [Google Scholar]
  23. Black FL. 1966. Measles endemicity in insular populations: critical community size and its implications.. J. Theor. Biol. 11:207–11 [Google Scholar]
  24. Black FL. 1975. Infectious diseases in primitive societies.. Science 187:515–18 [Google Scholar]
  25. Mitchison A. 1993. Will we survive?. Sci. Am. Sept 136–44 [Google Scholar]
  26. Humphry-Smith I, Donker G, Turzo A, Chastel C, Schmidt-Mayerova H. 1993. Evaluation of mechanical transmission of HIV by the African soft tick, Ornithodoros moubata.. AIDS 7:341–47 [Google Scholar]
  27. Garenne M, Aaby P. 1990. Pattern of exposure and measles mortality in Senegal.. J. Infect. Dis. 161:1088–94 [Google Scholar]
  28. Roberts L. 1989. Disease and death in the New World.. Science 246:1245–47 [Google Scholar]
  29. Black FL. 1992. Why did they die?. Science 258:1739–40 [Google Scholar]
  30. Black FL. 1994. An explanation of high death rates among New World peoples when in contact with Old World diseases.. Perspect. Biol. Med. 37:292–307 [Google Scholar]
  31. McNeill WH. 1976. Plagues and Peoples. Garden City, NY: Doubleday [Google Scholar]
  32. Monath TP. 1993. Arthropod-borne viruses.. See Ref. 156 62–71
  33. Darrow WW, Gorman EM, Glick BP. 1986. The social origins of AIDS: social change, sexual behavior, and disease trends. In The Social Dimensions of AIDS: Method and Theory, ed. DA Feldman, TM Johnson 95–107 New York: Praeger [Google Scholar]
  34. Tauxe RV, Puhr ND, Wells JD, Hargrette-Bean N, Blake PA. 1990. Antimicrobial resistance of Shigella isolated in the USA: the importance of international travelers.. J. Infect. Dis. 162:1107–11 [Google Scholar]
  35. Craven RB, Francy DB, Eliason DA. 1988. Importation of Aedes albopictus (Skuse) and other exotic mosquito species into the United States in used tires from Asia.. J. Am. Mosq. Contr. Assoc. 4:138–42 [Google Scholar]
  36. Francy DB, Karabatsos N, Wesson DM, Moore CG Jr, Lazuick JS. et al. 1990. A new arbovirus from Aedes albopictus, an Asian mosquito established in the United States.. Science 250:1738–40 [Google Scholar]
  37. Moore CG. 1988. Aedes albopictus in the USA: Rapid spread of a potential disease vector.. J. Am. Mosq. Contr. Assoc. 4:356–61 [Google Scholar]
  38. Henig RM. 1995. The new mosquito menace.. New York Times Sept 13
  39. Rohter L. 1995. U.S. may be threatened by epidemic of dengue.. New York Times International, Sept 23p
  40. Gizewski P, Homer-Dixon T. 1995. Urban Growth and Violence: Will the Future Resemble the Past? Washington, DC: Am. Assoc. Adv. Sci [Google Scholar]
  41. United Nations 1987. The Prospects of World Urbanization, Revised as of 1984–85. Population Studies. New York: United Nations [Google Scholar]
  42. Mckeown T. 1979. The Role of Medicine: Dream, Mirage, or Nemesis? Princeton, NJ: Princeton Univ. Press [Google Scholar]
  43. Snow J. 1855. On the Mode of Transmission of Cholera. London: Churchill [Google Scholar]
  44. McKeown T, Brown RG, Record RG. 1972. An interpretation of the modern rise of population in Europe.. Popul. Stud. 26:345–82 [Google Scholar]
  45. McKeown T, Record R, Turner R. 1974. An interpretation of the decline of mortality in England and Wales during the twentieth century.. Popul. Stud. 29:391–422 [Google Scholar]
  46. World Bank 1992. World Development Report 1992: Development and the Environment. Oxford: Oxford Univ. Press [Google Scholar]
  47. Morse SS. 1991. Emerging viruses: defining the rules for viral traffic.. Perspect. Biol. Med. 34:387–409 [Google Scholar]
  48. Bradley DJ. 1993b. Environmental and health problems of developing countries.. See Ref. 157 234–44
  49. Fear of an epidemic rises in Central America 1995c. New York Times Aug. 26 5
  50. Symons D. 1978. The Evolution of Human Sexuality. Oxford: Oxford Univ. Press [Google Scholar]
  51. Thrall PH, Antovics J, Hall DW. 1993. Host and pathogen coexistence in sexually transmitted and vector-borne diseases characterized by frequency-dependent disease transmission.. Am. Nat. 142:543–52 [Google Scholar]
  52. Ewald PW. 1994. Evolution of Infectious Disease. Oxford: Oxford Univ. Press [Google Scholar]
  53. Moser MR, Bender TR, Margolis HS. et al. 1979. Aircraft transmission of influenza A.. Am. J. Epidemiol. 110:1 [Google Scholar]
  54. Tolchin M. 1993. Exposures to tuberculosis on planes are investigated.. New York Times, June 21 11
  55. Percival V, Homer-Dixon T. 1995. Environmental Scarcity and Violent Conflict: The Case of Rwanda. Washington, DC: Am. Assoc. Adv. Sci [Google Scholar]
  56. Uvin P. 1996. Tragedy in Rwanda: The political ecology of conflict.. Environment 38:7–29 [Google Scholar]
  57. Stone R. 1993. Resurging infectious diseases in Russia.. Science 261:415 [Google Scholar]
  58. Maurice J. 1995. Russian chaos breeds diphtheria outbreak.. Science 267:1416–17 [Google Scholar]
  59. De Cock KM, McCormick JB. 1988. HIV infection in Zaire.. New Engl. J. Med. 319:309 [Google Scholar]
  60. Lastavica CC, Wilson ML. et al. 1989. Rapid emergence of a focal epidemic of Lyme disease in coastal Massachusetts.. New Engl. J. Med. 320:133–37 [Google Scholar]
  61. Barbour AG, Fish D. 1993. The biological and social phenomenon of Lyme disease.. Science 260:1610–16 [Google Scholar]
  62. Lederberg J, Shope RE, Oaks SC Jr. 1992. Emerging Infections: Microbial Threats to Health in the United States. Washington, DC: Natl. Acad [Google Scholar]
  63. Standaert SM, Dawson J, Schaffner W, Childs J, Biggie K, Singleton J Jr, Gerhardt R. 1995. Ehrlichiosis in a golf-oriented retirement community.. New Engl. J. Med. 333:420–25 [Google Scholar]
  64. Adler T. 1994. Tick threats: new diseases brought to you by your neighborhood ticks.. Sci. News 146:44–45 [Google Scholar]
  65. Smith CEG, Simpson DIH, Bowen ETW, Zlotnik I. 1967. Fatal human disease from vervet monkeys.. Lancet 2:1119–21 [Google Scholar]
  66. Kissling RE, Robinson RQ, Murphy FA, Whitfield SG. 1968. Agent of disease contracted from green monkeys.. Science 160:888–90 [Google Scholar]
  67. Brown AWA. 1977. Yellow fever, dengue and dengue haemorrhagic fever. In A World Geography of Human Diseases, ed. GM Howe 271–317 London: Academic [Google Scholar]
  68. Sutherst RW. 1993. Arthropods as disease vectors in a changing environment.. See Ref. 157 124–39
  69. Ehrlich PR, Ehrlich AH, Daily GC. 1995. The Stork and the Plow: The Equity Answer to the Human Dilemma. New York: Putnam [Google Scholar]
  70. World Health Organization 1976. Resistance of vectors and reservoirs of disease to pesticides Tech. Rep. No. 585. Washington, DC: World Health Org [Google Scholar]
  71. Chapin G, Wasserstrom R. 1981. Agricultural production and malaria resurgence in Central America and India.. Nature 293:181–85 [Google Scholar]
  72. Ehrlich PR. 1986. The Machinery of Nature. New York: Simon Schuster [Google Scholar]
  73. Georghiou GP. 1990. The effect of agrochemicals on vector populations. In Pesticide Resistance in Arthropods, ed. RT Roush, BE Tabashnik 183–202 New York: Chapman Hall [Google Scholar]
  74. Desowitz R. 1981. Tapeworms and Jewish Grandmothers. New York: Norton [Google Scholar]
  75. Almendares J, Sierra M, Anderson PK, Epstein PR. 1993. Critical regions, a profile of Honduras.. Lancet 342:1400–2 [Google Scholar]
  76. Epstein PR, Chickwenhere GP. 1994. Environmental factors in disease surveillance.. Lancet 343:1440–41 [Google Scholar]
  77. Mobarak AB. 1982. The schistosomiasis problem in Egypt.. Am. J. Trop. Med. Hyg. 31:87–91 [Google Scholar]
  78. Ehrlich PR, Ehrlich AH, Holdren JP. 1977. Ecoscience:Population, Resources, Environment. San Francisco: Freeman [Google Scholar]
  79. Van der Schalie H. 1974. Aswan dam revisited.. Environment 16:18–26 [Google Scholar]
  80. Davies FG, Linthicum KJ, James AD. 1981. Rainfall and epizootic Rift Valley fever.. Bull. World Health Org. 63:941–43 [Google Scholar]
  81. Meegan JM. 1978. Rift valley fever in Egypt: an overview of the epizootic in 1977 and 1978.. Controv. Epidemiol. Biostat. 3:100–13 [Google Scholar]
  82. Johnson KM. 1993. Emerging viruses in context: an overview of viral hemorrhagic fevers.. See Ref. 156 152–70
  83. Webster RG. 1993. Influenza.. See Ref. 156 37–45
  84. Morse SS. 1993. Examining the origins of emerging viruses.. See Ref. 156 10–28
  85. Scholtissek C, Naylor E. 1988. Fish farming and influenza pandemics.. Nature 331:215 [Google Scholar]
  86. Kipple KF. 1993. The Cambridge World History of Human Disease. Cambridge: Cambridge Univ. Press [Google Scholar]
  87. Murphy B. 1993. Factors restraining emergence of new influenza viruses.. See Ref. 156 234–40
  88. Schneider SH. 1994. Detecting climatic change signals: Are there any “fingerprints”?. Science 263:341–47 [Google Scholar]
  89. Smith JB, Tirpak DA. 1988. The Potential Effects of Global Climate Change on the United States.14 Washington, DC: US Environ. Prot. Agency [Google Scholar]
  90. Weihe WH, Mertens R. 1991. Human well-being, diseases and climate. In Climate Change: Science, Impacts and Policy, ed. J Jager, HL Ferguson 345–59 Cambridge: Cambridge Univ. Press [Google Scholar]
  91. Bradley DJ. 1993. Human tropical diseases in a changing environment.. See Ref. 157 146–62
  92. Gibbons A. 1992. Researchers fret over neglect of 600 million patients.. Science 256:1135 [Google Scholar]
  93. Haines A. 1990. Global warming: the implications for health. In Global Warming: The Greenpeace Report, ed. J Legget 149–62 Oxford: Oxford Univ. Press [Google Scholar]
  94. Shope R. 1991. Global climate change and infectious diseases.. Environ. Health Perspect 96:171–74 [Google Scholar]
  95. Dobson AP, Carper R. 1992. Global warming and potential changes in host-parasite and disease-vector relationships.. In Global Warming and Biodiversity, ed. RL Peters. New Haven, CT: Yale Univ. Press
  96. Martin PH, Lefebvre MG. 1995. Malaria and climate: sensitivity of malaria potential transmission to climate.. Ambio 24:200–7 [Google Scholar]
  97. Bouma MJ, Sondorp HE, van der Kaay HJ. 1994. Climate change and periodic epidemic malaria.. Lancet 343:1440 [Google Scholar]
  98. Loevinsohn ME. 1994. Climatic warming and increased malaria incidence in Rwanda.. Lancet 343:714–18 [Google Scholar]
  99. Epstein PR. 1994. Climate change played a role in India's plague.. New York Times Nov. 13 3
  100. Gillett JD. 1974. Direct and indirect influences of temperature on the transmission of parasites from insects to man.. In The Effects of Meteorological Factors upon Parasites. Symp. Brit. Soc. Parasitology, London, ed. AER Taylor, R Muller pp. 79–95
  101. Rogers DJ, Packer MJ. 1993. Vector-borne diseases, models, and global change.. Lancet 342:1282–85 [Google Scholar]
  102. Nichol ST, Spiropoulou CF, Morzunov S, Rollin PE, Ksiazek TG. et al. 1993. Genetic identification of a hantavirus associated with an outbreak of acute respiratory illness.. Science 262:914–17 [Google Scholar]
  103. Hughes JM, Peters CJ, Cohen ML, Mahy BWJ. 1993. Hantavirus pulmonary syndrome: an emerging infectious disease.. Science 262:850–51 [Google Scholar]
  104. Epstein PR. 1992a. Cholera and the environment.. Lancet 339:1167–68 [Google Scholar]
  105. Epstein PR, Ford TE, Colwell RR. 1993. Marine ecosystems.. Lancet 342:1216–19 [Google Scholar]
  106. Daily GC, Ehrlich PR. 1990. An exploratory model of the impact of rapid climate change on the world food situation.. Proc. R. Soc. Lond. B 2241:232–44 [Google Scholar]
  107. Smythe PM, Brereton-Stiles GG, Grace HJ, Mapoyane A, Schonland M. et al. 1971. Thymolymphatic deficiency and depression of cell-mediated immunity in protein-calorie malnutrition.. Lancet 2:939–43 [Google Scholar]
  108. Beisel WR. 1984. Nutrition, infection, specific immune responses, and nonspecific host defenses: a complex interaction. In Nutrition, Disease Resistance, and Immune Function, ed. RR Watson 21–30 New York: Marcel Dekker [Google Scholar]
  109. Harrison GA, Waterlow JC. 1990. Diet and Disease in Traditional Developing Societies. Cambridge: Cambridge Univ. Press [Google Scholar]
  110. Ellner PD, Neu HC. 1992. Understanding Infectious Disease. St. Louis, MO: Mosby-Year Book [Google Scholar]
  111. Dasgupta P. 1993. An Inquiry into Well-Being and Destitution. Oxford: Clarendon [Google Scholar]
  112. Chandra R. 1983. Nutrition, immunity, and infection: present knowledge and future directions.. Lancet 1:688–91 [Google Scholar]
  113. Chandra RK. 1981. Immunodeficiency in undernutrition and overnutrition.. Nutr. Rev. 39:225–31 [Google Scholar]
  114. Uvin P. 1994. The International Organization of Hunger. London: Kegan Paul [Google Scholar]
  115. Dumont R, Rosier B. 1969. The Hungry Future. New York: Praeger [Google Scholar]
  116. World Health Organization 1987. Int. Health News Sept 9 [Google Scholar]
  117. World Resources Institute 1987. World Resources 1987 New York: Basic [Google Scholar]
  118. UNICEF 1992. State of the World's Children 1992. New York: United Nations [Google Scholar]
  119. Ross PS, Visser IKG, Broeders HWJ, van de Bildt MWG, Bowen WD. et al. 1992. Antibodies to phocine distemper virus in Canadian seals.. Vet. Rec. 130:514–16 [Google Scholar]
  120. Repetto R. 1992. Policy Implications of Possible Effects of Pesticides on the Immune System.. Presented at Conf. Pestic. Health, Bellagio, Italy
  121. Calborn T, Dumanoski D, Myers J. 1996. Our Stolen Future. New York: Dutton [Google Scholar]
  122. Jones R, Wigley T. 1989. Ozone Depletion: Health and Environmental Consequences. New York: Wiley [Google Scholar]
  123. McCally M, Cassell C. 1990. Medical responsibility and the global environment.. Ann. Intern. Med. 113:467–73 [Google Scholar]
  124. Jeevan A, Kripke ML. 1993. Ozone depletion and the immune system.. Lancet 342:1159–60 [Google Scholar]
  125. Cherubin CE. 1971. Infectious disease problems of narcotic addicts.. Arch. Intern. Med. 128:309–13 [Google Scholar]
  126. Levine DP, Sobel JD. 1991. Infections in Intravenous Drug Abusers. Oxford: Oxford Univ. Press [Google Scholar]
  127. Sternberg S. 1994. The emerging fungal threat.. Science 266:1632–34 [Google Scholar]
  128. Georgopapadakou NH, Walsh TJ. 1994. Human mycoses: drugs and targets for emerging pathogens.. Science 264:371–73 [Google Scholar]
  129. Wilson EO. 1992. The Diversity of Life. Cambridge, MA: Harvard Univ. Press [Google Scholar]
  130. Lawton J, May R. 1995. Extinction Rates. Oxford: Oxford Univ. Press [Google Scholar]
  131. Daily GC, Ehrlich PR. 1995. Population extinction and the biodiversity crisis.. In Biodiversity Conservation, ed. CA Perrings, K-G Maler, C Folke, CS Holling, B-O Jansson. Dordrecht: Kluwer
  132. Daily GC. Nature's Services: Societal Dependence on Natural Ecosystems. Washington, DC: Island. In press [Google Scholar]
  133. Dolinger P, Ehrlich P, Fitch W, Breedlove D. 1973. Alkaloid and predation patterns in Colorado lupine populations.. Oecologia 13:191–204 [Google Scholar]
  134. Dowling HF. 1977. Fighting Infection. Cambridge, MA: Harvard Univ. Press [Google Scholar]
  135. Levy SB. 1992a. The Antibiotic Paradox. New York: Plenum [Google Scholar]
  136. Farnsworth NR. 1988. Screening plants for new medicines. In Biodiversity, ed. EO Wilson 83–97 Washington, DC: Natl. Acad [Google Scholar]
  137. Dobson A. 1995. Biodiversity and human health.. Trends Ecol. Evol. 10:390–91 [Google Scholar]
  138. Eisner T, Meinwald J. 1995. Proceedings of the colloquium on chemical ecology.. Proc. Natl. Acad. Sci. USA 92:1–82 [Google Scholar]
  139. Ehrlich PR, Holm RW. 1963. The Process of Evolution. New York: McGraw-Hill [Google Scholar]
  140. Lappe M. 1982. Germs That Won't Die. Garden City, NY: Anchor [Google Scholar]
  141. Slater AJ. 1989. Antibiotic resistance in the tropics. 3.. Medical responsibilities of the pharmaceutical industry with respect to use of antibiotics in the tropics Trans. R. Soc. Trop. Med. Hyg. 83:45–48 [Google Scholar]
  142. Cohen ML. 1992. Epidemiology of drug resistance: implications for a post-anti-microbial era.. Science 257:1050–55 [Google Scholar]
  143. Neu HC. 1992. The crisis in antibiotic resistance.. Science 257:1066–77 [Google Scholar]
  144. Russell AD. 1993. Microbial cell walls and resistance of bacteria and fungi to antibiotics and biocides.. J. Infect. Dis. 168:1339–40 [Google Scholar]
  145. May RM. 1993. Ecology and evolution of host-virus associations.. See Ref. 156 58–68
  146. Levy SB. 1992. Active efflux mechanisms for antimicrobial resistance.. Antimicrob. Agents Chemother. 36:695–703 [Google Scholar]
  147. Nikaido H. 1994. Prevention of drug access to bacterial targets: permeability barriers and active efflux.. Science 264:382–88 [Google Scholar]
  148. Davies J. 1994. Inactivation of antibiotics and the dissemination of resistance genes.. Science 264:375–82 [Google Scholar]
  149. Conway DJ, Greenwood BM, McBride SJ. 1991. The epidemiology of multiple-clone Plasmodium falciparum infections in Gambian patients.. Parasitology 103:1–6 [Google Scholar]
  150. Amabile-Cuevas CF, Chicurel ME. 1993. Horizontal gene transfer.. Sci. Am. 81:332–41 [Google Scholar]
  151. Alland JA. 1970. Adaptation in Cultural Evolution: An Approach to Medical Anthropology. New York: Columbia Univ. Press [Google Scholar]
  152. Lipsitch M. 1995. Fears growing over bacteria resistant to antibiotics.. New York Times, Sept 12
  153. Looareesuwan S, Viravan C, Vanijanonta S. et al. 1992. Randomized trial of artesunate and mefloquine alone and in sequence for acute uncomplicated falciparum malaria.. Lancet 339:821–24 [Google Scholar]
  154. Ter Kuiler FO, Dolan G, Nosten F, Edstein MD, Luxemburger C. et al. 1993. Halfantrine versus mefloquine in treatment of multidrug-resistant falciparum malaria.. Lancet 341:1044–49 [Google Scholar]
  155. Gay F, Ciceron L, Litaudon M. et al. 1994. In-vitro resistance of Plasmodium falciparum to qinghaosu derivatives in West Africa.. Lancet 343:850–51 [Google Scholar]
  156. Brown P. 1994. Deadly worm may be turning drug-resistant.. New Sci., 12 November 4 [Google Scholar]
  157. Holmberg SD, Osterholm MT, Senger KA, Cohen ML. 1984. Drug-resistant Salmonella from animals fed antimicrobials.. New Engl. J. Med. 311:617–22 [Google Scholar]
  158. Levy SB. 1984. Playing antibiotic pool: time to tally the score.. New Engl. J. Med. 311:617–22 [Google Scholar]
  159. Wuethrich B. 1994. Migrating genes could spread resistance.. New Sci., Oct. 15 9 [Google Scholar]
  160. Morse SS. ed 1993. Emerging Viruses. New York: Oxford Univ. Press [Google Scholar]
  161. Lake JV, Bock GR, Ackrill K. eds 1993. Environmental Change and Human Health. Chichester, UK: Wiley [Google Scholar]
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