1932

Abstract

Abstract

Wallerian degeneration (WD) is the set of molecular and cellular events by which degenerating axons and myelin are cleared after injury. Why WD is rapid and robust in the PNS but slow and incomplete in the CNS is a longstanding mystery. Here we review current work on the mechanisms of WD with an emphasis on deciphering this mystery and on understanding whether slow WD in the CNS could account for the failure of CNS axons to regenerate.

Loading

Article metrics loading...

/content/journals/10.1146/annurev.neuro.30.051606.094354
2007-07-21
2024-10-06
Loading full text...

Full text loading...

/content/journals/10.1146/annurev.neuro.30.051606.094354
Loading
/content/journals/10.1146/annurev.neuro.30.051606.094354
Loading

Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error