1932

Abstract

Capsid proteins of a number of plant viruses are permissive to genetic modifications in which foreign polypeptides are inserted in exposed loops or at their C termini. Plant viruses with these genetic alterations often grow at wild-type levels, providing gram quantities of modified viruses. Presented polypeptides studied most extensively correspond to antigenic epitopes of animal viruses and in some cases appropriately altered plant viruses generate neutralizing antibodies to the cognate animal virus when the plant virus is used as a vaccine. Structure-based analyses of these animal-plant virus chimeras have led to rational alterations to the presentation in efforts to increase the efficacy of the presented peptide.

Loading

Article metrics loading...

/content/journals/10.1146/annurev.phyto.35.1.67
1997-09-01
2024-06-14
Loading full text...

Full text loading...

/content/journals/10.1146/annurev.phyto.35.1.67
Loading
/content/journals/10.1146/annurev.phyto.35.1.67
Loading

Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error