Microglia Development and Function: Supplemental Video e

A supplemental video from the 2014 review by Debasis Nayak, Theodore L. Roth, and Dorian B. McGavern, "Microglia Development and Function," from the Annual Review of Immunology. 

In response to necrotic cell death, microglia become phagocytic and sometimes motile by first extending a single large circular extension toward the injured cell while retracting all other processes. The microglia soma is eventually pulled into the phagocytic extension along the thin connecting process.