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Annual Review of Analytical Chemistry

Volume 7, 2014

Ionophore-Based Optical Sensors

Abstract

This review provides an overview of the key aspects of designing ionophore-based optical sensors (IBOS). Exact response functions are developed and compared with a simplified, generalized equation. We also provide a brief introduction into less established but promising working principles, namely dynamic response and exhaustive exchange. Absorbance and fluorescence are the main optical readout strategies used in the evaluation of a sensor response, but they usually require a robust referencing technique for real-world applications. Established referencing schemes using IBOS as well as those from other optical sensors are also discussed. Finally, the power of recently developed photoresponsive ion extraction/release systems is outlined and discussed in view of dynamically switchable IBOS or regenerative exhaustive exchange IBOS.

Keyword(s): chemical mapping, ion sensing, pH cross sensitivity, photoresponsive ion sensors, referenced signals
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2014-06-12
2024-04-26
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Ionophore-Based Optical Sensors
Annual Review of Analytical Chemistry 7, 483 (2014); https://doi.org/10.1146/annurev-anchem-071213-020307
/content/journals/10.1146/annurev-anchem-071213-020307
/content/journals/10.1146/annurev-anchem-071213-020307
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