1932

Abstract

We review the recent developments in understanding the bacterial chemotaxis signaling pathway by using quantitative modeling methods. The models developed are based on structural information of the signaling complex and the dynamics of the underlying biochemical network. We focus on two important functions of the bacterial chemotaxis signaling pathway: signal amplification and adaptation. We describe in detail the structure and the dynamics of the mathematical models and how they compare with existing experiments, emphasizing the predictability of the models. Finally, we outline future directions for developing the modeling approach to better understand the bacterial chemosensory system.

Loading

Article metrics loading...

/content/journals/10.1146/annurev-biophys-083012-130358
2013-05-06
2024-12-13
Loading full text...

Full text loading...

/content/journals/10.1146/annurev-biophys-083012-130358
Loading
/content/journals/10.1146/annurev-biophys-083012-130358
Loading

Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error