1932

Abstract

Antimicrobial resistance is a complex, multifaceted, urgent global health problem. There is increasing concern about the emergence of multidrug-resistant superbugs. These superbugs result in infections responsive to treatment with few if any currently available antimicrobial agents, reviving memories of the preantibiotic era and evoking concerns about a postantibiotic era. Use of antibiotics exerts selective pressure on pathogens as well as on commensal organisms that are part of the normal flora of humans, animals, and the environment; this favors the emergence of resistant strains and sometimes involves the food supply. Addressing this urgent threat requires implementation of a multifaceted strategy that has been articulated in the past few years; implementation will require sustained political will, investment in systems and research, and a One Health approach involving improved communication, cooperation, and collaboration among the many professional disciplines and organizations with important roles to play at the intersection of human, animal, and environmental health. Priorities include strengthened human and animal health surveillance and monitoring for resistant organisms, antimicrobial stewardship programs, infection-control programs, development and approval of new antimicrobial agents, research on innovative therapeutic approaches, development of rapid diagnostic tests and new vaccines, and educational programs that target professional groups and the public.

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2016-02-28
2024-05-24
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Literature Cited

  1. Am. Vet. Med. Assoc 2008. One Health—what is One Health? Schaumburg, IL: Am. Vet. Med. Assoc https://www.avma.org/KB/Resources/Reference/Pages/One-Health94.aspx
  2. Antibiot. Resist. Proj 2010. Antibiotic-free food animal production: a profitable path from the farm to the table Issue Brief, Pew Campaign Hum. Health Ind. Farming, Washington, DC. http://www.pewtrusts.org/∼/media/legacy/uploadedfiles/phg/content_level_pages/issue_briefs/hhifibantibioticfreeproductionpdf.pdf
  3. Antibiot. Resist. Proj 2013. GAIN: How a new law is stimulating the development of antibiotics Issue Brief, Pew Charit. Trusts, Washington, DC. http://www.pewtrusts.org/en/research-and-analysis/issue-briefs/2013/11/07/gain-how-a-new-law-is-stimulating-the-development-of-antibiotics
  4. Assoc. Public Land-Grant Univ 2015a. Public Universities and Veterinary Medical College Task Force praises Obama budget funding to address antimicrobial resistance problem News Release, Jan. 28. http://www.aplu.org/news-and-media/News/public-universities-and-veterinary-medical-college-task-force-praises-obama-budget-funding-to-address-antimicrobial-resistance-problem
  5. Assoc. Public Land-Grant Univ., Assoc. of Am. Vet. Med. Colleges 2015b. Addressing Antibiotic Resistance: A Report from the Joint APLU/AAVMC Task Force on Antibiotic Resistance in Production Agriculture. http://www.aplu.org/projects-and-initiatives/agriculture-human-sciences-and-natural-resources/antibiotics-and-agriculture/final-report-october-2015.pdf
  6. Barton MD. 2014. Impact of antibiotic use in the swine industry. Curr. Opin. Microbiol. 19:9–15 [Google Scholar]
  7. Boucher HW, Talbot GH, Benjamin DK Jr, Bradley J, Guidos RJ. et al. 2013. 10ב20 Progress—development of new drugs active against gram-negative bacilli: an update from the Infectious Diseases Society of America. Clin. Infect. Dis. 56:1685–94 [Google Scholar]
  8. Brayton J. 2015. The White House hosts a forum on combating antibiotic resistance. The White House Blog June 2. https://www.whitehouse.gov/blog/2015/06/02/white-house-hosts-forum-combating-antibiotic-resistance
  9. Buchholz U, Bernard H, Werber D, Böhmer MM, Remschmidt C. et al. 2011. German outbreak of Escherichia coli O104:H4 associated with sprouts. N. Engl. J. Med. 365:1763–70 [Google Scholar]
  10. Byrne L, Fisher I, Peters R, Mather A, Thomson N. et al. 2014. A multi-country outbreak of Salmonella Newport gastroenteritis in Europe associated with watermelon from Brazil, confirmed by whole genome sequencing: October 2011 to January 2012. Eurosurveillance 19:pii=20866 [Google Scholar]
  11. Carlet J. 2015. The world alliance against antibiotic resistance: consensus for a declaration. Clin. Infect. Dis. 60:1837–41 [Google Scholar]
  12. CDC (Cent. Dis. Control Prev.) 1995. Foodborne Diseases Active Surveillance Network (FoodNet). Atlanta, GA: US Dep. Health Hum. Serv http://www.cdc.gov/foodnet/about.html [Google Scholar]
  13. CDC (Cent. Dis. Control Prev.) 2009. Transatlantic Task Force on Antimicrobial Resistance (TATFAR) Atlanta, GA: US Dep. Health Hum. Serv http://www.cdc.gov/drugresistance/tatfar/ [Google Scholar]
  14. CDC (Cent. Dis. Control Prev.) 2011. Global Health Programs: PulseNet International Atlanta, GA: US Dep. Health Hum. Serv http://www.cdc.gov/globalhealth/programs/pulsenet.htm
  15. CDC (Cent Dis. Control Prev.) 2013a. Antibiotic Resistance Threats in the United States, 2013. Atlanta, GA: US Dep. Health Hum. Serv http://www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf
  16. CDC (Cent. Dis. Control Prev.) 2013b. Global Foodborne Infections Network, Formerly Known as WHO Global Salm-Surv (GFN) Atlanta, GA: US Dep. Health Hum. Serv http://www.cdc.gov/ncezid/dfwed/international/gfin.html [Google Scholar]
  17. CDC (Cent. Dis. Control Prev.) 2013c. PulseNet Atlanta, GA: US Dep. Health Hum. Serv http://www.cdc.gov/pulsenet/
  18. CDC (Cent. Dis. Control Prev.) 2014a. Antibiotic resistance in foodborne germs is an ongoing threat. News Release, July 1. http://www.cdc.gov/media/releases/2014/p0701-antibiotic-resistance.html
  19. CDC (Cent. Dis. Control Prev.) 2014b. National Antimicrobial Resistance Monitoring System for Enteric Bacteria (NARMS): Human Isolates Final Report, 2012. Atlanta, GA: US Dept. Health Hum. Serv http://www.cdc.gov/narms/pdf/2012-annual-report-narms-508c.pdf [Google Scholar]
  20. Chan M. 2011. World Health Day 2011—combat drug resistance: no action today means no cure tomorrow. Media Statement, World Health Organ., April 6. http://www.who.int/mediacentre/news/statements/2011/whd_20110407/en/
  21. Chennai Declar. Team 2014. “Chennai Declaration”: 5-year plan to tackle the challenge of anti-microbial resistance. Indian J. Med. Microbiol. 32:221–28 [Google Scholar]
  22. Choffnes ER, Relman DA, Mack A. 2010. Antibiotic Resistance: Implications for Global Health and Novel Intervention Strategies: Workshop Summary Washington, DC: Natl. Acad. Press
  23. Choffnes ER, Relman DA, Mack A. 2012. Improving Food Safety Through A One Health Approach: Workshop Summary Washington, DC: Natl. Acad. Press
  24. Collignon P, Voss A. 2015. China, what antibiotics and what volumes are used in food production animals?. Antimicrob. Resist. Infect. Control 4:16 [Google Scholar]
  25. Consum. Rep 2012. Meat on Drugs. Yonkers, NY: Consum. Rep https://www.consumerreports.org/content/dam/cro/news_articles/health/CR%20Meat%20On%20Drugs%20Report%2006-12.pdf
  26. Consum. Rep 2014. Dangerous contaminated chicken: 97% of the breasts we tested harbored bacteria that could make you sick. Learn how to protect yourself. Consumer Reports February. http://www.consumerreports.org/cro/magazine/2014/02/the-high-cost-of-cheap-chicken/index.htm
  27. CSE (Cent. Sci. Environ.) Pollut. Monit. Lab 2014. Latest study by CSE's Pollution Monitoring Lab finds antibiotic residues in chicken. CSE Food Safety and Toxins New Delhi, India: Cent. Sci. Environ http://cseindia.org/content/latest-study-cse%E2%80%99s-pollution-monitoring-lab-finds-antibiotic-residues-chicken [Google Scholar]
  28. Dan. Vet. Food Adm 2015. About the Danish Veterinary and Food Administration. Glostrup, Denmark: Minist. Environ. Food http://www.foedevarestyrelsen.dk/english/Aboutus/Pages/default.aspx
  29. DANMAP (Dan. Integr. Antimicrob. Resist. Monit. Res. Prog.) 2015. About DANMAP. http://www.danmap.org/About%20Danmap.aspx
  30. Dep. Health, Prime Minist. Off 2014. Prime Minister warns of global threat of antibiotic resistance. News Release, July 2. https://www.gov.uk/government/news/prime-minister-warns-of-global-threat-of-antibio-tic-resistance
  31. Doyle MP, Erickson MC, Alali W, Cannon J, Deng X. et al. 2015. The food industry's current and future role in preventing microbial foodborne illness within the United States. Clin. Infect. Dis. 61:252–59 [Google Scholar]
  32. Dutil L, Irwin R, Finley R, Ng LK, Avery B. et al. 2010. Ceftiofur resistance in Salmonella enterica serovar Heidelberg from chicken meat and humans, Canada. Emerg. Infect. Dis. 16:48–54 [Google Scholar]
  33. ECDC-EFSA (Eur. Cent. Dis. Prev. Control-Eur. Food Saf. Auth.) 2014. Joint ECDC-EFSA rapid outbreak assessment: cluster of monophasic Salmonella Typhimurium with previously unseen MLVA pattern in the EU/EEA News Release, Sept. 5. http://ecdc.europa.eu/en/press/news/_layouts/forms/News_DispForm.aspx?List=8db7286c-fe2d-476c-9133-18ff4cb1b568&ID=1056
  34. Executive Off. Pres., Pres. Counc. Advis. Sci. Technol 2014. Report to the President on Combating Antibiotic Resistance. Washington, DC: Executive Off. Pres https://www.whitehouse.gov/sites/default/files/microsites/ostp/PCAST/pcast_carb_report_sept2014.pdf
  35. Exec. Order No. 13676 2014. Combating Antibiotic-Resistant Bacteria. 79 Fed. Reg. 56931 (Sept. 23, 2014) https://www.gpo.gov/fdsys/pkg/FR-2014-09-23/pdf/2014-22805.pdf
  36. FAO (Food Agric. Organ.), OIE (World Organ. Anim. Health), WHO (World Health Organ.) 2010. The FAO-OIE-WHO collaboration: sharing responsibilities and coordinating global activities to address health risks at the animal-human-ecosystems interfaces Concept Note. http://www.who.int/influenza/resources/documents/tripartite_concept_note_hanoi_042011_en.pdf
  37. Fauci AS, Collins FS. 2014. New strategies in battle against antibiotic resistance. NIH Director's Blog Sept. 18. http://directorsblog.nih.gov/2014/09/18/new-strategies-in-battle-against-antibiotic-resistance/
  38. FDA (Food Drug Adm.) 2011. Pathway to Global Product Safety Quality Silver Spring, MD: Food Drug Adm http://www.fda.gov/downloads/AboutFDA/CentersOffices/OfficeofGlobalRegulatoryOperati-onsandPolicy/GlobalProductPathway/UCM262528.pdf
  39. FDA (Food Drug Adm.) 2014. FDA secures full industry engagement on antimicrobial resistance strategy: issues first six-month progress report to update public on current and pending drug label changes News Release, June 30. http://www.fda.gov/AnimalVeterinary/NewsEvents/CVMUpdates/ucm403285.htm
  40. FDA (Food Drug Adm.) 2015. Veterinary feed directive final rule and next steps. Fact Sheet, Food Drug Adm., Silver Spring, MD. http://www.fda.gov/AnimalVeterinary/DevelopmentApprovalProcess/ucm449019.htm
  41. FDA (Food Drug Adm.) Cent. Vet. Med 2003. Evaluating the safety of antimicrobial new animal drugs with regard to their microbiological effects on bacteria of human health concern. Guidance for Industry #152, Food Drug Adm., Rockville, MD. http://www.fda.gov/downloads/AnimalVeterinary/GuidanceComplianceEnforcement/GuidanceforIndustry/ucm052519.pdf
  42. FDA (Food Drug Adm.) Cent. Vet. Med 2012. The judicious use of medically important antimicrobial drugs in food-producing animals Guidance for Industry #209, Food Drug Adm., Rockville, MD. http://www.fda.gov/downloads/AnimalVeterinary/GuidanceComplianceEnforcement/GuidanceforIndustry/UCM216936.pdf
  43. FDA (Food Drug Adm.) Cent. Vet. Med 2013. New animal drugs and new animal drug combination products administered in or on medicated feed or drinking water of food-producing animals: recommendations for drug sponsors for voluntarily aligning product use conditions with GFI #209 Guidance for Industry #213, Food Drug Adm., Rockville, MD. http://www.fda.gov/downloads/AnimalVeterinary/GuidanceComplianceEnforcement/GuidanceforIndustry/UCM299624.pdf
  44. Franko E. 2014. Global antibiotic consumption soars 36% in 10 years, raising concerns about superbugs News Release, July 9, CDDEP (Cent. Dis. Dyn. Econ. Policy) Res. News Washington, DC: http://www.cddep.org/blog/posts/global_antibiotic_consumption_soars_36_10_years_raising_concerns_about_superbugs
  45. Frieden T. 2013. Stopping the threat of anti-microbial resistance. Pres. Counc. Advis. Sci. Technol., CDC (Cent. Dis. Control Prev.), Washington, DC. https://www.whitehouse.gov/sites/default/files/microsites/ostp/PCAST/Frieden_PCAST%20Slide%20Presentation_FINAL.pdf
  46. Fukuda K. 2015. Food safety in a globalized world. Bull. World Health Organ. 93:212 [Google Scholar]
  47. Gibbs SEJ, Gibbs EPJ. 2013. The historical, present, and future role of veterinarians in One Health. One Health: The Human-Animal-Environment Interfaces in Emerging Infectious Diseases. The Concept and Examples of a One Health Approach JS MacKenzie, M Jeggo, P Daszak, JA Richt 31–48 Berlin/Heidelberg, Ger.: Springer-Verlag [Google Scholar]
  48. Hammerum AM, Larsen J, Andersen VD, Lester CH, Skovgaard Skytte TS. et al. 2014. Characterization of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli obtained from Danish pigs, pig farmers and their families from farms with high or no consumption of third- or fourth-generation cephalosporins. J. Antimicrob. Chemother. 69:2650–57 [Google Scholar]
  49. Harrison EM, Weinert LA, Holden MT, Welch JJ, Wilson K. et al. 2014. A shared population of epidemic methicillin-resistant Staphylococcus aureus 15 circulates in humans and companion animals. mBio 5:e00985–13 [Google Scholar]
  50. He M, Miyajima F, Roberts P, Ellison L, Pickard DJ. et al. 2013. Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nat. Genet. 45:109–13 [Google Scholar]
  51. Hughes JM. 2011. Preserving the lifesaving power of antimicrobial agents. JAMA 305:1027–28 [Google Scholar]
  52. Infect. Dis. Soc. Am 2010. The 10ב20 Initiative: pursuing a global commitment to develop 10 new antibacterial drugs by 2020. Clin. Infect. Dis. 50:1081–83 [Google Scholar]
  53. Infect. Dis. Soc. Am., Spellberg B, Blaser M, Guidos RJ, Boucher HW, et al. 2011. Combating antimicrobial resistance: policy recommendations to save lives. Clin. Infect. Dis. 52:Suppl. 5S397–428 [Google Scholar]
  54. Khabbaz RF, Moseley RR, Steiner RJ, Levitt AM, Bell BP. 2014. Challenges of infectious diseases in the USA. Lancet 384:53–63 [Google Scholar]
  55. Knetsch CW, Connor TR, Mutreja A, van Dorp SM, Sanders IM. et al. 2014. Whole genome sequencing reveals potential spread of Clostridium difficile between humans and farm animals in the Netherlands, 2002 to 2011. Eurosurveillance 19:pii=20954 [Google Scholar]
  56. Krans B. 2014. Consumers steer clear of meat raised with antibiotics. Healthline July 24. http://www.healthline.com/health/antibiotics/consumers-migrating-away-factory-farms
  57. Kwong JC, Maaten S, Upshur RE, Patrick DM, Marra F. 2009. The effect of universal influenza immunization on antibiotic prescriptions: an ecological study. Clin. Infect. Dis. 49:750–56 [Google Scholar]
  58. Larson C. 2015. China's lakes of pig manure spawn antibiotic resistance. Science 347:6223704 [Google Scholar]
  59. Laxminarayan R. 2014. India must limit availability of stronger antibiotics. Deutsche Welle Dec. 12. http://dw.com/p/1E3Mb
  60. Layne N. 2015. Exclusive: Costco working to end use of human antibiotics in chicken. Reuters March 6. http://www.reuters.com/article/2015/03/06/us-costco-antibiotics-idUSKBN0M201520150306
  61. Lederberg J, Shope RE, Oaks JSC. 1992. Emerging Infections: Microbial Threats to Health in the United States Washington, DC: Natl. Acad. Press
  62. Lushniak B. 2014. Surgeon General's perspectives. Public Health Rep. 129:112–14 [Google Scholar]
  63. Mackenzie JS, Jeggo M, Daszak P, Richt JA. 2013a. Current Topics in Microbiology and Immunology 366 One Health: The Human-Animal-Environment Interfaces in Emerging Infectious Diseases—Food Safety and Security, and International and National Plans for Implementation of One Health Activities Berlin/Heidelberg, Ger.: Springer-Verlag
  64. Mackenzie JS, Jeggo M, Daszak P, Richt JA. 2013b. Current Topics in Microbiology and Immunology 365 One Health: The Human-Animal-Environment Interfaces in Emerging Infectious Diseases—The Concept and Examples of a One Health Approach Berlin/Heidelberg, Ger.: Springer-Verlag
  65. Majowicz SE, Musto J, Scallan E, Angulo FJ, Kirk M. et al. 2010. The global burden of nontyphoidal Salmonella gastroenteritis. Clin. Infect. Dis. 50:882–89 [Google Scholar]
  66. McEachran AD, Blackwell BR, Hanson JD, Wooten KJ, Mayer GD. et al. 2015. Antibiotics, bacteria, and antibiotic resistance genes: aerial transport from cattle feed yards via particulate matter. Environ. Health Perspect. 123:337–43 [Google Scholar]
  67. Metz M, Shlaes DM. 2014. Eight more ways to deal with antibiotic resistance. Antimicrob. Agents Chemother. 58:4253–56 [Google Scholar]
  68. Minist. Agric. Agrofood For 2012. National action plan for the reduction of the risks of antibiotic resistance in veterinary medicine Rep., Minist. Agric. Agrofood For., Paris. http://frenchfoodintheus.org/wp-content/uploads/PDF/PlanABR-complet-BD_cle8ea7f1-2.pdf
  69. Molbak K, Simonsen J, Jorgensen CS, Krogfelt KA, Falkenhorst G. et al. 2014. Seroincidence of human infections with nontyphoid Salmonella compared with data from public health surveillance and food animals in 13 European countries. Clin. Infect. Dis. 59:1599–606 [Google Scholar]
  70. NIAID (Natl. Inst. Allerg. Infect. Dis.) 2014. NIAID's Antibacterial Resistance Program: Current Status and Future Directions. Washington, DC: Dept. Health Hum. Serv http://www.niaid.nih.gov/topics/antimicrobialresistance/documents/arstrategicplan2014.pdf
  71. Niman Ranch 2015. We go beyond natural. https://www.nimanranch.com/about-us/faq/
  72. Nizet V. 2015. Stopping superbugs, maintaining the microbiota. Sci. Transl. Med. 7:295ed8 [Google Scholar]
  73. One Health Work. Group 2010. Veterinary services 2015 project: One Health strategic direction. Rep., US Dep. Agric. Anim. Plant Health Insp. Serv. Vet. Serv. https://www.aphis.usda.gov/animal_health/one_health/downloads/one_health_strategic_direction.pdf
  74. Overdevest I, Willemsen I, Rijnsburger M, Eustace A, Xu L. et al. 2011. Extended-spectrum β-lactamase genes of Escherichia coli in chicken meat and humans, The Netherlands. Emerg. Infect. Dis. 17:1216–22 [Google Scholar]
  75. Parmley J, Leung Z, Leger D, Finley R, Irwin R. et al. 2012. One Health and food safety—the Canadian experience: a holistic approach toward enteric bacterial pathogens and antimicrobial resistance surveillance. Improving Food Safety Through a One Health Approach ER Choffnes, DA Relman, L Olsen, R Hutton, A Mack 176–88 Washington, DC: Natl. Acad. Press [Google Scholar]
  76. Pew Charit. Trusts 2015. Antibiotic resistance project. http://www.pewtrusts.org/en/projects/antibiotic-resistance-project
  77. Polansek T. 2014. Big U.S. school districts plan switch to antibiotic-free chicken. Reuters Dec. 9. http://www.reuters.com/article/2014/12/10/us-antibiotics-chicken-education-idUSKBN0JO00320141210
  78. Rev. Antimicrob. Resist 2014. Antimicrobial resistance: tackling a crisis for the health and wealth of nations. Rep., Rev. Antimicrob. Resist., London. http://amr-review.org/sites/default/files/AMR%20Review%20Paper%20-%20Tackling%20a%20crisis%20for%20the%20health%20and%20wealth%20of%20nations_1.pdf
  79. Rev. Antimicrob. Resist 2015a. Tackling a global health crisis: initial steps. Rep., Rev. Antimicrob. Resist., London. https://amr-review.org/sites/default/files/Report-52.15.pdf
  80. Rev. Antimicrob. Resist 2015b. Rapid diagnostics: stopping unnecessary use of antibiotics. London. http://amr-review.org/sites/default/files/Paper-Rapid-Diagnostics-Stopping-Unnecessary-Prescription.pdf
  81. Rinsky JL, Nadimpalli M, Wing S, Hall D, Baron D. et al. 2013. Livestock-associated methicillin and multidrug resistant Staphylococcus aureus is present among industrial, not antibiotic-free livestock operation workers in North Carolina. PLOS ONE 8:e67641 [Google Scholar]
  82. S-FAR (Stakehold. Forum Antimicrob. Resist.) 2014. A U.S. National Plan to Combat Antimicrobial Resistance: Ensuring Coordination, Transparency, and Accountability through Meaningful and Sustained Stakeholder Engagement. Presented at US Stakehold. Forum Antimicrob. Resist. (S-FAR) Inaug. Meet., Oct. 9, Philadelphia, PA
  83. Scallan E, Griffin PM, Angulo FJ, Tauxe RV, Hoekstra RM. 2011a. Foodborne illness acquired in the United States—unspecified agents. Emerg. Infect. Dis. 17:16–22 [Google Scholar]
  84. Scallan E, Hoekstra RM, Angulo FJ, Tauxe RV, Widdowson M-A. et al. 2011b. Foodborne illness acquired in the United States—major pathogens. Emerg. Infect. Dis. 17:7–15 [Google Scholar]
  85. Silva C, Calva E, Maloy S. 2014. One Health and food-borne disease: Salmonella transmission between humans, animals, and plants. One Health: People, Animals, and the Environment RM Atlas, S Maloy 137–48 Washington, DC: Am. Soc. Microbiol. [Google Scholar]
  86. Smith TC. 2015. Livestock-associated Staphylococcus aureus: the United States experience. PLOS Pathog. 11:e1004564 [Google Scholar]
  87. Smolinski MS, Hamburg MA, Lederberg J. 2003. Microbial Threats to Health: Emergence, Detection, and Response Washington, DC: Natl. Acad. Press
  88. Soc. Healthc. Epidemiol. Am., Infect. Dis. Soc. Am., Pediatr. Infect. Dis. Soc 2012. Policy statement on antimicrobial stewardship by the Society for Healthcare Epidemiology of America (SHEA), the Infectious Diseases Society of America (IDSA), and the Pediatric Infectious Diseases Society (PIDS). Infect. Control Hosp. Epidemiol. 33:322–27 [Google Scholar]
  89. Spellberg B, Guidos R, Gilbert D, Bradley J, Boucher HW. et al. 2008. The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America. Clin. Infect. Dis. 46:155–64 [Google Scholar]
  90. Swann MM. 1969. Report of the Joint Commission on the use of antibiotics in animal husbandry and veterinary medicine. London: Her Majesty's Station. Off. [Google Scholar]
  91. Tauxe RV, Doyle MP, Kuchenmuller T, Schlundt J, Stein CE. 2010. Evolving public health approaches to the global challenge of foodborne infections. Int. J. Food Microbiol. 139:Suppl. 1S16–28 [Google Scholar]
  92. Taylor MR. 2011. Will the Food Safety Modernization Act help prevent outbreaks of foodborne illness?. N. Engl. J. Med. 365:e18 [Google Scholar]
  93. Trust Am. Health 2014. TFAH issues statement on the threat of antibiotic resistance, recommends government take additional action News Release, Sept. 18. http://healthyamericans.org/newsroom/releases/?releaseid=314
  94. Tsalik EL. 2014. Antimicrobial drug resistance in all four corners of the earth. Sci. Transl. Med. 6:240ec103 [Google Scholar]
  95. UK Dep. Health 2013. UK Five Year Antimicrobial Resistance Strategy 2013 to 2018. London: UK Dep. Health https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/244058/20130902_UK_5_year_AMR_strategy.pdf
  96. US Dep. Agric 2014. Antimicrobial Resistance Action Plan. Washington, DC: US Dep. Agric http://www.usda.gov/documents/usda-antimicrobial-resistance-action-plan.pdf
  97. US Dep. Agric. Anim. Plant Health Insp. Serv 2015. National Animal Health Monitoring System (NAHMS). http://www.aphis.usda.gov/wps/portal/aphis/ourfocus/animalhealth?1dmy&urile=wcm%3apath%3a%2Faphis_content_library%2Fsa_our_focus%2Fsa_animal_health%2Fsa_monitoring_and_surveillance%2Fsa_nahms%2Fct_national_animal_health_monitoring_system_nahms_home
  98. Vaccines Eur 2013. Role of vaccination in reducing antimicrobial resistance Rep., Vaccines Eur., Brussels. http://www.vaccineseurope.eu/wp-content/uploads/2013/09/AMR-and-Vaccines-June-2013.pdf
  99. Van Boeckel TP, Gandra S, Ashok A, Caudron Q, Grenfell BT. et al. 2014. Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data. Lancet Infect. Dis. 14:742–50 [Google Scholar]
  100. van Walle I. 2013. ECDC starts pilot phase for collection of molecular typing data. Eurosurveillance 18:pii=20357 [Google Scholar]
  101. Watts G. 2014. UK declares war on antimicrobial resistance. Lancet 384:391 [Google Scholar]
  102. Wegener HC. 2012. Antibiotic resistance—linking human and animal health. Improving Food Safety Through a One Health Approach ER Choffnes, DA Relman, L Olsen, R Hutton, A Mack 331–49 Washington, DC: Natl. Acad. Press [Google Scholar]
  103. White House 2014. National strategy for combating antibiotic-resistant bacteria. Rep., The White House, Washington, DC. https://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf
  104. White House 2015. National action plan for combating antibiotic-resistant bacteria (CARB) Rep., The White House, Washington, DC. https://www.whitehouse.gov/sites/default/files/docs/national_action_plan_for_combating_antibotic-resistant_bacteria.pdf [Google Scholar]
  105. White House Off. Press Secr 2015. Fact sheet: the global health security agenda. News Release, July 28. https://www.whitehouse.gov/the-press-office/2015/07/28/fact-sheet-global-health-security-agenda
  106. WHO (World Health Organ.) 2013. Meeting of the Strategic and Technical Advisory Group: Global Strategy for tackling antimicrobial resistance (STAG-AMR). Summary statement from meeting of 1st STAG-AMR World Health Organ. http://www.who.int/drugresistance/stag/STAG_AMR_Sept_2013_Summay_on_web.pdf?ua=1 [Google Scholar]
  107. WHO (World Health Organ.) 2014a. Antimicrobial Resistance: Global Report on Surveillance Geneva: World Health Organ.
  108. WHO (World Health Organ.) 2014b. Draft global action plan on antimicrobial resistance: draft for consultation with Member States October 2014 Rep., World Health Organ., Geneva. http://www.who.int/drugresistance/AMR_DRAFT_GAP_1_Oct_2014_for_MS_consultation.pdf
  109. WHO (World Health Organ.) 2015a. What to do about resistant bacteria in the food-chain?. Bull. World Health Organ 93:4209–84 [Google Scholar]
  110. WHO (World Health Organ.) 2015b. World Health Assembly addresses antimicrobial resistance, immunization gaps and malnutrition News Release, May 25. http://www.who.int/mediacentre/news/releases/2015/wha-25-may-2015/en
  111. WHO (World Health Organ.) 2015c. Worldwide Country Situation Analysis: Response to Antimicrobial Resistance Geneva: World Health Organ.
  112. WHO (World Health Organ.) Advis. Group Integr. Surveill. Antimicrob. Resist 2012. Critically Important Antimicrobials for Human Medicine, 3rd Revision Geneva: World Health Organ.
  113. WHO (World Health Organ.) Media Cent 2013. Salmonella (non-typhoidal). Fact Sheet 139, World Health Organ., Geneva. http://www.who.int/mediacentre/factsheets/fs139/en
  114. WHO (World Health Organ.) 2000. WHO Principles for the Containment of Antimicrobial Resistance in Animals Intended for Food: Report of a WHO Consultation with the participation of the Food and Agriculture Organization of the United Nations and the Office International des Epizooties. Geneva: World Health Organ http://apps.who.int/iris/bitstream/10665/68931/1/WHO_CDS_CSR_APH_2000.4.pdf
  115. Wielinga PR. 2013. Food safety: at the center of a One Health approach for combating zoonoses. One Health: The Human-Animal-Environment Interfaces in Emerging Infectious Diseases. Food Safety and Security, and International and National Plans for Implementation of One Health Activities JS MacKenzie, M Jeggo, P Daszak, JA Richt 3–18 Berlin/Heidelberg, Ger.: Springer-Verlag [Google Scholar]
  116. World Health Assem 2014. Antimicrobial resistance (Item 16.5) Presented at World Health Assem., 67th, May 24, Geneva. http://apps.who.int/gb/ebwha/pdf_files/WHA67/A67_R25-en.pdf [Google Scholar]
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