1932

Abstract

Mechanosensitive ion channels are gated directly by physical stimuli and transduce these stimuli into electrical signals. Several criteria must apply for a channel to be considered mechanically gated. Mechanosensitive channels from bacterial systems have met these criteria, but few eukaryotic channels have been confirmed by the same standards. Recent work has suggested or confirmed that diverse types of channels, including TRP channels, K channels, MscS-like proteins, and DEG/ENaC channels, are mechanically gated. Several studies point to the importance of the plasma membrane for channel gating, but intracellular and/or extracellular structures may also be required.

Loading

Article metrics loading...

/content/journals/10.1146/annurev.biophys.37.032807.125836
2010-06-09
2024-06-23
Loading full text...

Full text loading...

/content/journals/10.1146/annurev.biophys.37.032807.125836
Loading
/content/journals/10.1146/annurev.biophys.37.032807.125836
Loading

Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error