1932

Abstract

Endoderm, one of the three principal germ layers, contributes to all organs of the alimentary tract. For simplicity, this review divides formation of endodermal organs into four fundamental steps: () formation of endoderm during gastrulation, () morphogenesis of a gut tube from a sheet of cells, () budding of organ domains from the tube, and () differentiation of organ-specific cell types within the growing buds. We discuss possible mechanisms that regulate how undifferentiated endoderm becomes specified into a myriad of cell types that populate the respiratory and gastrointestinal tracts.

Loading

Article metrics loading...

/content/journals/10.1146/annurev.cellbio.15.1.393
1999-11-01
2024-06-18
Loading full text...

Full text loading...

/content/journals/10.1146/annurev.cellbio.15.1.393
Loading
/content/journals/10.1146/annurev.cellbio.15.1.393
Loading

Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error