Plant pathology evolved from its mycology-oriented origins into a science dealing with biochemical mechanisms of diseases, along with enhanced crop production through disease control. This retrospective describes first my personal experience from my introduction to plant pathology, to the establishment of the concept of accessibility as a model pertaining to genetically defined basic compatibility induced by pathogens. I then refer to the development of molecular plant pathology from physiological and biochemical plant pathology fostered by the growth in recombinant technology in the second half of the past century. This progress was best reflected by the U.S.-Japan Seminar Series held at 4–5-year intervals from 1966 to 2003 and documented by publications in major journals of our discipline. These seminars emphasized that progress in science has always been supported by the invention of novel techniques and that knowledge integrated from modern genomics and subsequent proteomics should contribute to the progress of basic life sciences and, more importantly, to the elaboration of rational measures for disease control.


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Literature Cited

  1. Akai S, Ouchi S. eds. 1971. Morphological and Biochemical Events in Plant-Parasite Interaction Tokyo: Phytopathol. Soc. Jpn.415 pp.This publication contains the proceedings of the second U.S.-Japan Seminar. [Google Scholar]
  2. Akimitsu K, Ohtani K, Matsunaka A, Yamasaki Y, Katoh H, Yamamoto H. 2005. Role of mitochondrial gene controlling specificity in plant disease. See Ref. 58 pp. 258–69
  3. Asada Y, Bushnell WR, Ouchi S, Vance CP. eds. 1982. Plant Infection: The Physiological and Biochemical Basis Tokyo/Berlin: Jpn. Sci. Soc. Press/Springer Verlag.362 pp.This publication contains the proceedings of the fourth U.S.-Japan Seminar. [Google Scholar]
  4. Axtell MJ, Staskawicz BJ. 2003. Initiation of RPS2-specified disease resistance in Arabisopsis is coupled to the AvrRpt2-directed elimination of RIN4. Cell 112:369–77 [Google Scholar]
  5. Bateman DF. 1967. Alteration of cell wall components during pathogenesis by Rhizoctonia solani. See Ref. 40 pp. 58–79
  6. Bushnell WR. 1996. Progress in understanding host-parasite interaction—the US-Japan seminar series, 1966–1985. See Ref. 39 pp. 3–14
  7. Carver TLW, Robbins MP, Thomas BJ, Troth K, Raistrick N, Zeyen RJ. 1998. Silicon deprivation enhances localized autofluorescence responses and phenylalanine ammonia-lyase activity in oat attacked by Blumeria graminis. Physiol. Mol. Plant Pathol. 52:245–57 [Google Scholar]
  8. Chen MS, Fitzgerald HA, Yadav RC, Canias PE, Dong X, Ronald PC. 2001. Evidence for a disease-resistance pathway in rice similar to the NPR1-mediated signaling pathway in Arabidopsis. Plant J. 27:101–13 [Google Scholar]
  9. Collmer A, Bronstein PA, Schechter LM, Shimizu R. 2005. Functional genomic analysis of Pseudomonas syringae-plant interactions. See Ref. 58 pp. 11–19
  10. Daly JM, Uritani I. eds. 1979. Recognition and Specificity in Plant Host-Parasite Interactions Tokyo/Baltimore: Jpn. Sci. Soc. Press/Univ. Park Press.355 pp.This publication contains the proceedings of the third U.S.-Japan Seminar. [Google Scholar]
  11. Dangle JL, Jones JDG. 2001. Plant pathogens and integrated defence response to infection. Nature 411:826–33 [Google Scholar]
  12. Dannon EA, Wydra K. 2004. Interaction between silicon amendment, bacterial wilt development and phenotype of Ralstonia solanacearum in tomato genotype. Physiol. Mol. Plant Pathol. 64:233–43 [Google Scholar]
  13. Dimond AE. 1971. Birth and progress in the study of pathogenesis. See Ref. 1 pp. 1–24
  14. Doke N, Park H-J, Katou S, Komatsubara H, Makino T. et al. 2001. The oxidative burst in plants: Mechanism and function in induced resistance. See Ref. 27 pp. 184–93
  15. Ellingboe AH. 1979. Inheritance of specificity: the gene-for-gene hypothesis. See Ref. 11 pp. 3–17
  16. Flor HH. 1971. Current status of the gene-for-gene concept. Annu. Rev.Phytopathol. 9:275–96 [Google Scholar]
  17. Friedrich L, Lawton K, Dietrich R, Willits M, Cada R, Ryals J. 2001. NIM1 overexpression in Arabidopsis potentiates plant disease resistance and results in enhanced effectiveness of fungicides. Mol. Plant Microbe Interact. 14:1114–24 [Google Scholar]
  18. Fujita K, Suzuki T, Kunoh H, Carver TLW, Thomas BJ. et al. 2004. Induced inaccessibility in barley cells exposed to extracellular material released by non-pathogenic powdery mildew conidia. Physiol. Mol. Plant Pathol. 64:169–78 [Google Scholar]
  19. Gäumann E. 1951. Pflanzliche InfektionslehreLehrbuch der Algemeine Pflanzenbiologie, für Biologen, Landwirte, Forster und Pflanzenzuchter Basel: Verlag Birkhauser.681 pp. , 2nd ed.. [Google Scholar]
  20. Ghanmi D, McNally DJ, Banhamou N, Menzies JG, Bèlange RR. 2004. Powdery mildew of Arabisopsis thaliana: a pathosystem for exploring the role of silicon in plant-microbe interactions. Physiol. Mol. Plant Pathol. 64:189–99 [Google Scholar]
  21. Grell MN, Holm KB, Giese H. 2005. Two novel Blumeria graminis f.sp. hordei genes are induced in planta and up-regulated in mlo virulent isolates. Physiol. Mol. Plant Pathol. 66:79–89 [Google Scholar]
  22. Ichinose Y, Taguchi F, Takeuchi K, Marutani M, Ishiga Y. et al. 2005. Bacterial flagellins as elicitors of the defense response. See Ref. 58 pp. 83–91
  23. Jurnak F, Heron SR, Scavetta RD. 2001. Understanding pectate lyase C at the atomic level. See Ref. 27 pp. 54–67
  24. Keen NT. 1982. Phytoalexins—progress in regulation of their accumulation in gene-for-gene interactions. See Ref. 3 pp. 281–99
  25. Keen NT. 1990. Gene-for-gene complementarity. Annu. Rev. Genet. 24:447–63 [Google Scholar]
  26. Keen NT. 1991. Characterization and function of bacterial avirulence genes. See Ref. 50 pp. 59–67
  27. Keen NT, Mayama S, Leach JE, Tsuyumu S. eds. 2001. Delivery and Perception of Pathogen Signals in Plants St. Paul, MN: APS Press.268 pp.This publication contains the proceedings of the eighth U.S.-Japan Seminar. [Google Scholar]
  28. Kobayashi I, Watanabe H, Kunoh H. 1995. Induced accessibility and enhanced inaccessibility at the cellular level in barley coleoptiles. XIV. Evidence for elicitor(s) and suppressor(s) of host inaccessibility from Erysiphe graminis. Physiol. Mol. Plant Pathol. 46:445–56 [Google Scholar]
  29. Kosuge T, Yamada T. 1987. Virulence determinants in plant pathogen interactions. See Ref. 44 pp. 171–83
  30. Kunoh H. 1987. Induced susceptibility and enhanced resistance at the cellular level in barley coleoptiles. See Ref. 44 pp. 59–73
  31. Kunoh H. 1996. Cytological approaches in understanding host-parasite interactions. See Ref. 39 pp. 15–29
  32. Kunoh H, Kobayashi I, Yamaoka N. 1991. Recognition of fungal nonpathogens by plant cells at the penetration stage. See Ref. 50 pp. 189–201
  33. Leach JE, Liu B, Manosalva P, Wu C, Wu J. et al. 2005. Dissection of durable resistance in rice. See Ref. 58 pp. 164–73
  34. Lyngkjaer MF, Carver TLW, Zeyen RJ. 2001. Virulent Blumeria graminis infection induced penetration susceptibility and suppresses race-specific hypersensitive resistance against avirulent attack in Mla1 barley. Physiol. Mol. Plant Pathol. 59:243–56 [Google Scholar]
  35. Martin G, Frederick R, Thilmony R, Zhou J. 1996. Signal transduction events involved in bacterial speck disease resistance. See Ref. 39 pp. 163–76
  36. Mayama S, Tada Y, Hata S, Takata Y, Yao N. et al. 2001. Apoptotic response in defense of oats to infections and elicitors. See Ref. 27 pp. 220–28
  37. Mills D, Niepold F. 1987. Molecular analysis of pathogenesis of Pseudomonas syringae pv. syringae.. See Ref. 44 pp. 185–200
  38. Mills D, Mukhopadhyay P, Zhao Y, Romantschuk M. 1991. Organization and function of pathogenicity genes of Pseudomonas syringae pathovars phaseolicola and syringae. See Ref. 50 pp. 69–81
  39. Mills D, Kunoh H, Keen NT, Mayama S. ed. 1996. Molecular Aspects of Pathogenicity and Resistance: Requirement for Signal Transduction St.Paul, MN: APS Press.294 pp.This publication contains the proceedings of the seventh U.S.-Japan Seminar. [Google Scholar]
  40. Mirocha CJ, Uritani I. eds. 1967. The Dynamic Role of Molecular Constituents in Plant-Parasite Interaction St. Paul, MN: APS Press.372 pp.This publication contains the proceedings of the first U.S.-Japan Seminar. [Google Scholar]
  41. Naito N, Ouchi S. 1956. Occurrence of the Gladiolus leaf spot caused by Curvularia lunata in Japan. Tech. Bull. Kagawa Agrc. Coll. 7:135–43 [Google Scholar]
  42. Nester EW. 1979. Molecular studies on crown gall tumors. See Ref. 10 pp. 289–300
  43. Nester E, Wood D, Lu P. 2005. Global analysis of Agrobacterium-plant interactions. See Ref. 58 pp. 1–10
  44. Nishimura S, Vance CP, Doke N. eds. 1987. Molecular Determinants of Plant Diseases Tokyo/Berlin: Jpn. Sci. Soc. Press/Springer Verlag.293 pp.This publication contains the proceedings of the fifth U.S.-Japan Seminar. [Google Scholar]
  45. Otani H, Kohnobe A, Narita M, Shiomi H, Kodama M, Kohmoto K. 2001. A new type of host-selective toxin, a protein from Alternaria alternata. See Ref. 27 pp. 68–76
  46. Ouchi S. 1983. Induction of resistance or susceptibility. Annu. Rev. Phytopathol. 21:289–315 [Google Scholar]
  47. Ouchi S. 2001. Biotechnology as an approach to improving disease resistance in plants. See Ref. 27 pp. 251–64
  48. Ouchi S, Lindegren CC. 1963. Genic interaction in Saccharomyces. Can. J. Genet. Cytol. 5:257–67 [Google Scholar]
  49. Ouchi S, Oku H. 1982. Physiological basis of susceptibility induced by pathogens. See Ref. 3 pp. 117–36
  50. Patil SS, Ouchi S, Mills D, Vance CP. eds. 1991. Molecular Strategies of Pathogens and Host Plants New York: Springer Verlag.268 pp.This publication contains the proceedings of the sixth U.S.-Japan Seminar. [Google Scholar]
  51. Scheffer RP, Pringle RB. 1967. Pathogen-produced determinants of disease and their effects on host plants. See Ref. 40 pp. 217–26
  52. Sequeira L. 2001. Delivery of pathogen signals: historical approach. See Ref. 27 pp. 12–24
  53. Shiraishi T, Toyoda K, Yamada T, Ichinose Y, Kiba A. et al. 2001. Suppressors of defense—supprescins and plant receptor molecules. See Ref. 27 pp. 112–21
  54. Shiraishi T, Toyoda K, Kiba A, Kawahara T, Takahashi H. et al. 2005. Defense signaling and the plant cell wall—a new signaling pathway dependent upon inorganic phosphate. See Ref. 58 pp. 114–25
  55. Tani T. 2001. Perception of pathogen signals to initiate active defense. See Ref. 27 pp. 1–11
  56. Tsuge T, Hatta E, Ito K, Tanaka T, Ruswandi SR. et al. 2005. Conditionally dispensable chromosomes controlling pathogenicity of Alternaria alternata. See Ref. 58 pp. 50–60
  57. Tsuyumu S, Miura R, Nishio S. 1991. Distinct induction of pectinases as a factor determining host specificity of soft-rotting Erwinia. See Ref. 50 pp. 31–43
  58. Tsuyumu S, Leach JE, Shiraishi T, Wolpert T. eds. 2005. Genomic and Genetic Analysis of Plant Parasitism St. Paul, MN: APS Press.301 pp.This publication contains the proceedings of the ninth U.S.-Japan Seminar. [Google Scholar]
  59. Ueno T, Nakashima T, Fukami H. 1982. Chemical basis of host recognition by Alternaria species. See Ref. 3 pp. 235–51
  60. Van der Biezenn EA, Jones JDG. 1998. Plant disease-resistance proteins and the gene-for-gene concept. Trends Biochem. Sci. 23:454–56 [Google Scholar]
  61. VanEtten HD. 1982. Phytoalexin detoxification by monooxigenases and its importance for pathogeniocity. See Ref. 3 pp. 315–27
  62. Wolpert TJ, Coffeen WC, Curtis MJ, Lorang JM. 2001. Victorin, apotosis and mitochondrion. See Ref. 27 pp. 97–111
  63. Ziphel C, Robatzek S, Navarro L, Oakeley EJ, Jones DG. 2004. Bacterial disease resistance in Arabidopsis through flagellin perception. Nature 428:764–67 [Google Scholar]

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